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Article
Class I and II human leukocyte antibodies in pediatric haploidentical allograft candidates: prevalence and risk factors
Donor-specific anti-human leukocyte antigen (HLA) antibodies (DSAs) were associated with graft failure (GF) following haploidentical stem cell transplantation (Haplo-HSCT). The prevalence and risk factors of D...
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Article
Open AccessOncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling
Retinoid X receptor-alpha (RXRα) is a potent regulator of inflammatory responses; however, its therapeutic potential for inflammatory cancer remains to be explored. We previously discovered that RXRα is abnorm...
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Article
Open AccessA rigid and healable polymer cross-linked by weak but abundant Zn(II)-carboxylate interactions
Achieving a desirable combination of solid-like properties and fast self-healing is a great challenge due to slow diffusion dynamics. In this work, we describe a design concept that utilizes weak but abundant ...
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Article
Open AccessMutations in the P10 region of procaspase-8 lead to chemotherapy resistance in acute myeloid leukemia by impairing procaspase-8 dimerization
Caspase-8 activation initiates apoptotic signaling cascades, and certain mutations in procasepase-8 have been reported to be associated with the progression and prognosis of different types of tumors. In this ...
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Article
Open AccessComplete genome sequence of Citrobacter werkmanii strain BF-6 isolated from industrial putrefaction
In our previous study, Citrobacter werkmanii BF-6 was isolated from an industrial spoilage sample and demonstrated an excellent ability to form biofilms, which could be affected by various environmental factors. ...
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Article
A Critical Role for IL-21 Receptor Signaling in the Coxsackievirus B3-Induced Myocarditis
To determine whether IL-21 receptor signaling plays a significant role in promoting Tfh cell-mediated cardiac injury in viral myocarditis (VMC), we compared IL-21R-deficient mice for some parameters of VMC. Ba...
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Article
Detection of HF-ERW status by neural network on imaging
To achieve online testing of high-frequency electric resistance welding (HF-ERW) tube quality, forecasting models were established for welding defect conditions with collected high-speed images of the joint me...
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Article
Single Nucleotide Polymorphisms in SLC19A1 and SLC25A9 Are Associated with Childhood Autism Spectrum Disorder in the Chinese Han Population
Genetic variants have been implicated in the development of autism spectrum disorder (ASD). Recent studies suggest that solute carriers (SLCs) may play a role in the etiology of ASD. This purpose of this study...
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Article
Open AccessMicroRNA-122 as a predictor of HBsAg seroclearance in hepatitis B and C dual infected patients treated with interferon and ribavirin
It has been demonstrated that microRNA-122 (miR-122) plays key roles in the modulation of hepatitis B virus (HBV) replication. This study examined the role of miR-122 in patients with hepatitis C virus (HCV)-H...
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Article
Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Article
Open AccessIncreased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti-ANT antoantibody
Recently, a new subset of CD4+T helper cell termed Follicular helper T cells (Tfh), which play a pivotal role in B cell activation and differentiation in lymphoid structures, has been reported to participate in s...
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Article
Design and fabrication of a valveless micropump based on low temperature co-fired ceramic tape technology
Low temperature co-fired ceramic (LTCC) tape technology has been widely studied in microsystems and microfluidic devices. The current study presented the manufacturing process of a simple and inexpensive micro...
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Article
Open AccessImpact of matrix metalloproteinase-8 gene variations on the risk of thoracic aortic dissection in a Chinese Han population
The importance of matrix metalloproteinase 8 (MMP8) expression during the progression of thoracic aortic dissection (TAD) has been recently emphasized. Genetic variations that affect proteinase expression or a...
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Article
Mechano growth factor (MGF) promotes proliferation and inhibits differentiation of porcine satellite cells (PSCs) by down-regulation of key myogenic transcriptional factors
Porcine satellite cells represent an ideal model system for studying the cellular and molecular basis regulating myogenic stem cell proliferation and differentiation and for exploring the experimental conditio...
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Article
Liver stiffness measurement in the risk assessment of hepatocellular carcinoma for patients with chronic hepatitis
The risk of hepatocellular carcinoma (HCC) increased with progression of hepatic fibrosis as assessed by liver stiffness measurement (LSM). This study used LSM to assess the risk of HCC presence in patients wi...
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Abstracts for the 6th Congress of Asian Sleep Research Society
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Article
Microstructure and Hardness of T250 Maraging Steel in Heat Affected Zone
Electron-beam (EB) welding was used in T250 maraging steel, microstructures of both base material and heat affected zone (HAZ) were investigated by optical microscopy (OM), scanning electron microscopy (SEM) a...
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Article
Screen p53 mutations in hepatocellular carcinoma by FASAY: A novel splicing mutation
To establish a routine procedure for the detection of p53 mutations in hepatocellular carcinoma (HCC) surgical resections using the FASAY (functional analysis of separated alleles of p53 on yeast) procedure.
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Article
Experiments and homogeneous turbulence model of boiling flowin narrow channels
The boiling heat transfer experiments have been carried out in vertical narrow annular channels with pure water. A two-dimensional homogeneous turbulence model of boiling flow has been developed and solved num...
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Article
Motor driving leg design for bionic crab-like robot
The paper presents the design of walking leg for bionics crab-like robot, which is driven with micro servo motor. The kinematic characteristics of the bionics machine are analysed for optimized structure param...