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1,221 Result(s)
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Article
Global H. pylori recurrence, recrudescence, and re-infection status after successful eradication in pediatric patients: a systematic review and meta-analysis
Little information is available regarding global H. pylori recurrence, recrudescence, and re-infection in pediatric patients after successful eradication, nor are their influencing factors clear. We conducted a s...
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Modeling and Analysis of Flow Through the Orifice of Still in Dilution Refrigerator
The cooling capacity of a typical dilution refrigerator is mainly determined by the circulating flow of the He-3 in the system, which is usually realized by the external circulation pump. In order to increase ...
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Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes
The High Altitude Detection of Astronomical Radiation (HADAR) experiment, which was constructed in Tibet, China, combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity ...
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Desloratadine ameliorates paclitaxel-induced peripheral neuropathy and hypersensitivity reactions in mice
Paclitaxel (PTX) serves as a primary chemotherapy agent against diverse solid tumors including breast cancer, lung cancer, head and neck cancer and ovarian cancer, having severe adverse effects including PTX-i...
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A multi-objective optimization based on machine learning for dimension precision of wax pattern in turbine blade manufacturing
Wax pattern fabrication in the investment casting of hollow turbine blades directly determines the dimension accuracy of subsequent casting, and therefore significantly affects the quality of final product. In...
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Open AccessCirc-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9
CircRNAs are covalently closed, single-stranded RNA that form continuous loops and play a crucial role in the initiation and progression of tumors. Cancer stem cells (CSCs) are indispensable for cancer develop...
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Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation
Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal medicine XueBi**g with conventional procedures reduces the...
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Article
Sex differences orchestrated by androgens at single-cell resolution
Sex differences in mammalian complex traits are prevalent and are intimately associated with androgens1–7. However, a molecular and cellular profile of sex differences and their modulation by androgens is still l...
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Desloratadine alleviates ALS-like pathology in hSOD1G93A mice via targeting 5HTR2A on activated spinal astrocytes
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with progressive loss of motor neurons in the spinal cord, cerebral cortex and brain stem. ALS is characterized by gradual muscle atroph...
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Open AccessClinical significance and potential pathogenesis of VCAN in adult non-cystic fibrosis bronchiectasis: a retrospective study
The pathogenesis of adult non-cystic fibrosis (CF) bronchiectasis is complex, and the relevant molecular mechanism remains ambiguous. Versican (VCAN) is a key factor in inflammation through interactions with a...
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Distinct element method simulation of mechanical properties of material layer of pellet belt roasting machine
The thick layer and graded feeding technology of a belt roasting machine is an effective method for improving the production efficiency and quality index of pellet production, and a reasonable design of the me...
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In vivo manufacture and manipulation of CAR-T cells for better druggability
The current CAR-T cell therapy products have been hampered in their druggability due to the personalized preparation required, unclear pharmacokinetic characteristics, and unpredictable adverse reactions. Enab...
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Open AccessThe requirement of the mitochondrial protein NDUFS8 for angiogenesis
Mitochondria are important for the activation of endothelial cells and the process of angiogenesis. NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8) is a protein that plays a critical role in the functi...
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Open AccessNonlinear optical diode effect in a magnetic Weyl semimetal
Diode effects are of great interest for both fundamental physics and modern technologies. Electrical diode effects (nonreciprocal transport) have been observed in Weyl systems. Optical diode effects arising fr...
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Structure of GPR101–Gs enables identification of ligands with rejuvenating potential
GPR101 is an orphan G protein-coupled receptor actively participating in energy homeostasis. Here we report the cryo-electron microscopy structure of GPR101 constitutively coupled to Gs heterotrimer, which rev...
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Reduced PATL2 Impairs the Proliferation of Ovarian Granulosa Cells by Decreasing ADM2 Expression in Patients with PCOS
It is recognized that PCOS patients are often accompanied with aberrant follicular development, which is an important factor leading to infertility in patients. However, the relevant regulatory mechanisms of a...
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Comparison of Short-Term Outcomes After Robotic Versus Laparoscopic Radical Gastrectomy for Advanced Gastric Cancer in Elderly Individuals: A Propensity Score-Matching Study
Robotic gastrectomy (RG) has been widely used to treat gastric cancer. However, whether the short-term outcomes of robotic gastrectomy are superior to those of laparoscopic gastrectomy (LG) for elderly patient...
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Jacobi sums over Galois rings of arbitrary characters and their applications in constructing asymptotically optimal codebooks
Codebooks with small maximum cross-correlation amplitudes are used to distinguish the signals from different users in multiple access communication systems in code division. Firstly, this paper studies the Jac...
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Open AccessCorrection: c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses
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Open AccessNucleic-acid-base photofunctional cocrystal for information security and antimicrobial applications
Cocrystal engineering is an efficient and simple strategy to construct functional materials, especially for the exploitation of novel and multifunctional materials. Herein, we report two kinds of nucleic-acid-...