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  1. No Access

    Article

    Global H. pylori recurrence, recrudescence, and re-infection status after successful eradication in pediatric patients: a systematic review and meta-analysis

    Little information is available regarding global H. pylori recurrence, recrudescence, and re-infection in pediatric patients after successful eradication, nor are their influencing factors clear. We conducted a s...

    Lu Xu, **ao-Ting Li, Ishtiaq Ur-Rahman, Chen Zhang in Journal of Gastroenterology (2024)

  2. No Access

    Article

    Modeling and Analysis of Flow Through the Orifice of Still in Dilution Refrigerator

    The cooling capacity of a typical dilution refrigerator is mainly determined by the circulating flow of the He-3 in the system, which is usually realized by the external circulation pump. In order to increase ...

    De-Ming Wang, Wei-Pei Cha, Wei-Dong Ding in Journal of Low Temperature Physics (2024)

  3. No Access

    Article

    Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes

    The High Altitude Detection of Astronomical Radiation (HADAR) experiment, which was constructed in Tibet, China, combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity ...

    Ao-Yan Cheng, Hao Cai, Shi Chen, Tian-Lu Chen, **ang Dong in Nuclear Science and Techniques (2024)

  4. No Access

    Article

    Desloratadine ameliorates paclitaxel-induced peripheral neuropathy and hypersensitivity reactions in mice

    Paclitaxel (PTX) serves as a primary chemotherapy agent against diverse solid tumors including breast cancer, lung cancer, head and neck cancer and ovarian cancer, having severe adverse effects including PTX-i...

    Jian Lu, Xue-jian Zhao, Yuan Ruan, **ao-**g Liu, Xuan Di in Acta Pharmacologica Sinica (2024)

  5. No Access

    Article

    A multi-objective optimization based on machine learning for dimension precision of wax pattern in turbine blade manufacturing

    Wax pattern fabrication in the investment casting of hollow turbine blades directly determines the dimension accuracy of subsequent casting, and therefore significantly affects the quality of final product. In...

    **g Dai, Song-Zhe Xu, Chao-Yue Chen, Tao Hu, San-San Shuai in Advances in Manufacturing (2024)

  6. Article

    Open Access

    Circ-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9

    CircRNAs are covalently closed, single-stranded RNA that form continuous loops and play a crucial role in the initiation and progression of tumors. Cancer stem cells (CSCs) are indispensable for cancer develop...

    Qi-Yue Chen, Kai-**ang Xu, **ao-Bo Huang, Deng-Hui Fan in Communications Biology (2024)

  7. No Access

    Article

    Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation

    Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal medicine XueBi**g with conventional procedures reduces the...

    Chen Cheng, Chao Ren, Mu-zi Li, Yi-hui Liu, Ren-qi Yao in Acta Pharmacologica Sinica (2024)

  8. No Access

    Article

    Sex differences orchestrated by androgens at single-cell resolution

    Sex differences in mammalian complex traits are prevalent and are intimately associated with androgens17. However, a molecular and cellular profile of sex differences and their modulation by androgens is still l...

    Fei Li, Xudong **ng, Qiqi **, **ang-Ming Wang, Pengfei Dai, Ming Han, Huili Shi in Nature (2024)

  9. No Access

    Article

    Desloratadine alleviates ALS-like pathology in hSOD1G93A mice via targeting 5HTR2A on activated spinal astrocytes

    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with progressive loss of motor neurons in the spinal cord, cerebral cortex and brain stem. ALS is characterized by gradual muscle atroph...

    Jian Lu, An-xu He, Zhuo-ying **, Meng Zhang, Zhong-xin Li in Acta Pharmacologica Sinica (2024)

  10. Article

    Open Access

    Clinical significance and potential pathogenesis of VCAN in adult non-cystic fibrosis bronchiectasis: a retrospective study

    The pathogenesis of adult non-cystic fibrosis (CF) bronchiectasis is complex, and the relevant molecular mechanism remains ambiguous. Versican (VCAN) is a key factor in inflammation through interactions with a...

    Wan-Ying Huang, Kang-Kang Hong, Rong-Quan He, **g Luo in BMC Pulmonary Medicine (2024)

  11. No Access

    Article

    Distinct element method simulation of mechanical properties of material layer of pellet belt roasting machine

    The thick layer and graded feeding technology of a belt roasting machine is an effective method for improving the production efficiency and quality index of pellet production, and a reasonable design of the me...

    Yin-hua Tang, **ng-wang Li, Xu Gao, Tao Yang in Journal of Iron and Steel Research Interna… (2024)

  12. No Access

    Article

    In vivo manufacture and manipulation of CAR-T cells for better druggability

    The current CAR-T cell therapy products have been hampered in their druggability due to the personalized preparation required, unclear pharmacokinetic characteristics, and unpredictable adverse reactions. Enab...

    Rui Hou, **aoxue Zhang, Xu Wang, Xuan Zhao, Si** Li in Cancer and Metastasis Reviews (2024)

  13. Article

    Open Access

    The requirement of the mitochondrial protein NDUFS8 for angiogenesis

    Mitochondria are important for the activation of endothelial cells and the process of angiogenesis. NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8) is a protein that plays a critical role in the functi...

    Qian-wei **ong, Kun Jiang, **ao-wei Shen, Zhou-rui Ma in Cell Death & Disease (2024)

  14. Article

    Open Access

    Nonlinear optical diode effect in a magnetic Weyl semimetal

    Diode effects are of great interest for both fundamental physics and modern technologies. Electrical diode effects (nonreciprocal transport) have been observed in Weyl systems. Optical diode effects arising fr...

    Christian Tzschaschel, Jian-**ang Qiu, Xue-Jian Gao, Hou-Chen Li in Nature Communications (2024)

  15. No Access

    Article

    Structure of GPR101–Gs enables identification of ligands with rejuvenating potential

    GPR101 is an orphan G protein-coupled receptor actively participating in energy homeostasis. Here we report the cryo-electron microscopy structure of GPR101 constitutively coupled to Gs heterotrimer, which rev...

    Zhao Yang, Jun-Yan Wang, Fan Yang, Kong-Kai Zhu, Guo-Peng Wang in Nature Chemical Biology (2024)

  16. No Access

    Article

    Reduced PATL2 Impairs the Proliferation of Ovarian Granulosa Cells by Decreasing ADM2 Expression in Patients with PCOS

    It is recognized that PCOS patients are often accompanied with aberrant follicular development, which is an important factor leading to infertility in patients. However, the relevant regulatory mechanisms of a...

    Jun Tan, Pei-Pei Liu, Li-Yun Cao, Yang Zou, Zi-Yu Zhang in Reproductive Sciences (2024)

  17. No Access

    Article

    Comparison of Short-Term Outcomes After Robotic Versus Laparoscopic Radical Gastrectomy for Advanced Gastric Cancer in Elderly Individuals: A Propensity Score-Matching Study

    Robotic gastrectomy (RG) has been widely used to treat gastric cancer. However, whether the short-term outcomes of robotic gastrectomy are superior to those of laparoscopic gastrectomy (LG) for elderly patient...

    Zhi-Wei Zheng MD, Mi Lin MD, Hua-Long Zheng MD in Annals of Surgical Oncology (2024)

  18. No Access

    Article

    Jacobi sums over Galois rings of arbitrary characters and their applications in constructing asymptotically optimal codebooks

    Codebooks with small maximum cross-correlation amplitudes are used to distinguish the signals from different users in multiple access communication systems in code division. Firstly, this paper studies the Jac...

    Deng-Ming Xu, Gang Wang, Sihem Mesnager, You Gao in Designs, Codes and Cryptography (2024)

  19. Article

    Open Access

    Correction: c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses

    Xu-Yan Wang, Yuan Wei, Bo Hu, Yuan Liao in Signal Transduction and Targeted Therapy (2024)

  20. Article

    Open Access

    Nucleic-acid-base photofunctional cocrystal for information security and antimicrobial applications

    Cocrystal engineering is an efficient and simple strategy to construct functional materials, especially for the exploitation of novel and multifunctional materials. Herein, we report two kinds of nucleic-acid-...

    Wenqing Xu, Guanheng Huang, Zhan Yang, Ziqi Deng, Chen Zhou in Nature Communications (2024)

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