139 Result(s)
within
**an-wen Zhang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessIndole diketopiperazines from endophytic Chaetomium sp 88194 induce breast cancer cell apoptotic death
Diketopiperazines are important secondary metabolites of the fungi with variety bioactivities. Several species belonging to genus Chaetomium produce compounds of this class, such as chetomin. To identify new anti...
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Open AccessAn Integrated Metagenomics/Metaproteomics Investigation of the Microbial Communities and Enzymes in Solid-state Fermentation of Pu-erh tea
Microbial enzymes during solid-state fermentation (SSF), which play important roles in the food, chemical, pharmaceutical and environmental fields, remain relatively unknown. In this work, the microbial commun...
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Open AccessFlower evolution of alpine forbs in the open top chambers (OTCs) from the Qinghai-Tibet Plateau
Effects of global changes on biodiversity have been paid more and more attention world widely and the open top chambers (OTCs) are the most common tools to study the effects of climatic warming on plant divers...
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Open AccessPiezoelectric effect in chemical vapour deposition-grown atomic-monolayer triangular molybdenum disulfide piezotronics
High-performance piezoelectricity in monolayer semiconducting transition metal dichalcogenides is highly desirable for the development of nanosensors, piezotronics and photo-piezotransistors. Here we report th...
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The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming
Extensive reprogramming of cellular energy metabolism is a hallmark of cancer. Despite its importance, the molecular mechanism controlling this tumour metabolic shift remains not fully understood. Here we show...
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Open AccessPrognostic value of the primary lesion apparent diffusion coefficient (ADC) in nasopharyngeal carcinoma: a retrospective study of 541 cases
The prognostic value of the primary lesion pretreatment apparent diffusion coefficient (ADC), which is obtained by diffusion-weighted magnetic resonance imaging (MR-DWI), remains unknown in nasopharyngeal carc...
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Open AccessPharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers
K-601 is an herbal formulation for influenza consisting of Lonicera japonica, Isatis indigotica, Rheum palmatum, Phellodendron chinense and Scutellaria baicalensis. In this work, we characterized the chemical con...
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Open AccessHsa-miR-19a is associated with lymph metastasis and mediates the TNF-α induced epithelial-to-mesenchymal transition in colorectal cancer
Lymph node metastasis is an important factor determining the outcome of colorectal cancer. Although epithelial-to-mesenchymal transition (EMT), TNF-α and microRNA (miRNA) have been found to play important role...
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Open AccessThe inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism
Prostate cancer at advanced stages including metastatic and castration-resistant cancer remains incurable due to the lack of effective therapies. MiR-190a belongs to the small noncoding RNA family and has an i...
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Open AccessCoumarin derivatives from Ainsliaea fragrans and their anticoagulant activity
Coumarin derivatives are an important class of C6–C3 plant metabolites that show a variety of bioactivities. Currently, most clinical anticoagulant agents are coumarins, such as warfarin, dicoumarol and acenocoum...
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Article
Open AccessSymmetry-protected transport in a pseudospin-polarized waveguide
If a system possesses a spin or pseudospin, which is locked to the linear momentum, spin-polarized states can exhibit backscattering-immune transport if the scatterer does not flip the spin. Good examples of s...
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Open AccessUltra-high-resolution 3D digitalized imaging of the cerebral angioarchitecture in rats using synchrotron radiation
The angioarchitecture is a fundamental aspect of brain development and physiology. However, available imaging tools are unsuited for non-destructive cerebral map** of the functionally important three-dimensi...
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Open AccessThe functional gene composition and metabolic potential of coral-associated microbial communities
The phylogenetic diversity of coral-associated microbes has been extensively examined, but some contention remains regarding whether coral-associated microbial communities are species-specific or site-specific...
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Open AccessTractography-based Parcellation of the Human Middle Temporal Gyrus
The middle temporal gyrus (MTG) participates in a variety of functions, suggesting the existence of distinct functional subregions. In order to further delineate the functions of this brain area, we parcellate...
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Open AccessSuhuang antitussive capsule at lower doses attenuates airway hyperresponsiveness, inflammation and remodeling in a murine model of chronic asthma
Suhuang antitussive capsule (Suhuang), a traditional Chinese medication, is found effective in treating chronic cough and cough variant asthma (CVA). This study aimed to determine the possible effects and unde...
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Open AccessSelf-induced synthesis of phase-junction TiO2 with a tailored rutile to anatase ratio below phase transition temperature
The surface phase junction of nanocrystalline TiO2 plays an essential role in governing its photocatalytic activity. Thus, facile and simple methods for preparing phase-junction TiO2 photocatalysts are highly des...
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Open AccessLow c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas
Aberrant c-Met has been implicated in the development of many cancers. The objective of this study was to identify an unfavorable prognostic marker that might guide decisions regarding clinical treatment strat...
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Open AccessSimulating the Kibble-Zurek mechanism of the Ising model with a superconducting qubit system
The Kibble-Zurek mechanism (KZM) predicts the density of topological defects produced in the dynamical processes of phase transitions in systems ranging from cosmology to condensed matter and quantum materials...
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Open AccessmiR-93 functions as an oncomiR for the downregulation of PDCD4 in gastric carcinoma
Programmed cell death 4 (PDCD4), as a tumor suppressor gene, is frequently reduced in a variety of tumors, including gastric cancer. Previous findings have indicated that PDCD4 participates in tumorigenesis th...
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Open AccessConsolidative treatment after salvage chemotherapy improves prognosis in patients with relapsed extranodal natural killer/T-cell lymphoma
The optimal treatment strategy for relapsed natural killer/T-cell lymphoma (NKTCL) remains largely unknown. We retrospectively reviewed the treatment modalities and prognosis of 56 relapsed NKTCL patients. Che...
