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1,613 Result(s)
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Article
Open AccessAMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...
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Open AccessAmplitude analysis of the \( {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma \) decay
The resonant structure of the radiative decay Λ b 0 ...
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Open AccessCholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...
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Open AccessStrain to shine: stretching-induced three-dimensional symmetries in nanoparticle-assembled photonic crystals
Stretching elastic materials containing nanoparticle lattices is common in research and industrial settings, yet our knowledge of the deformation process remains limited. Understanding how such lattices reconf...
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Paeoniflorin regulates RhoA/ROCK1 and Nrf2 pathways in PDLIM1-dependent or independent manners in oxidative stressed melanocytes
The adhesive properties of vitiligo melanocytes have decreased under oxidative stress., cytoskeleton proteins can control cell adhesion. Paeoniflorin (PF) was proved to resist hydrogen peroxide (H2O2)-induced oxi...
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Open AccessNeoadjuvant camrelizumab (an anti-PD-1 antibody) plus chemotherapy or apatinib (a VEGFR-2 inhibitor) for initially unresectable stage II–III non-small-cell lung cancer: a multicentre, two-arm, phase 2 exploratory study
This multicentre, two-arm, phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell l...
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AHNAK2 Regulates NF-κB/MMP-9 Signaling to Promote Pancreatic Cancer Progression
Early metastasis of pancreatic cancer (PaC) is a major cause of its high mortality rate. Previous studies have shown that AHNAK2 is involved in the progression of some tumors and is predicted to be an independ...
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Property evolution and service life prediction of novel metallic materials for future lunar bases
While lunar bases have been a focus of development in recent years, the complex and extreme environment of the lunar surface remains a considerable challenge for lunar exploration. Unlike those on Earth, lunar...
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Open AccessBenefit finding among family caregivers of patients with advanced cancer in a palliative treatment: a qualitative study
Benefit finding is the search for positive meaning from traumatic events, such as cancer. It can help caregivers have a positive experience in the caregiving process, relieve negative emotions, and reduce care...
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Open AccessThe nuclear and mitochondrial genome assemblies of Tetragonisca angustula (Apidae: Meliponini), a tiny yet remarkable pollinator in the Neotropics
The field of bee genomics has considerably advanced in recent years, however, the most diverse group of honey producers on the planet, the stingless bees, are still largely neglected. In fact, only eleven of t...
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Cooperative enhancement of mechanical and tribological properties through tailoring TiN transition interface in boron nitride nanosheets reinforced copper composites
Strengthening interface bonding between boron nitride nanosheets (BNNS) and copper matrix is an essential prerequisite for exploiting a new generation of copper matrix composites (CMCs) with high strength and ...
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Salinity affects C/N ratio through differential responses of carbon and nitrogen metabolism in mangrove Avicennia marina leaves revealed by combined analysis of transcriptome and metabolome
Salt is a critical environmental factor that profoundly impacts plant growth and development. However, the investigation into how plants regulate carbon and nitrogen metabolism in response to different levels ...
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Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the dysfunction and progressive death of cerebral and spinal motor neurons. Preliminary epidemiological research has hinted a...
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MnO2/Poly-L-lysine Co-decorated Carbon Fiber Cloth with Decreased Evaporation Enthalpy and Enhanced Photoabsorption/Antibacterial Performance for Solar-Enabled Anti-fouling Seawater Desalination
Solar-driven seawater evaporation is a potential strategy for mitigating global freshwater shortage, but its application is hindered by the photothermal membranes with high evaporation enthalpy, unsatisfactory...
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Open AccessAssociation between exposure to metalworking fluid aerosols, occupational noise and chronic kidney disease: a cross-sectional study in China
Chronic kidney disease (CKD) carries a high public health burden yet little is known about the relationship between metalworking fluid (MWF) aerosols, occupational noise and CKD. We aimed to explore the relati...
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Effect of Low Plasma Spraying Power on Anode Microstructure and Performance for Metal-Supported Solid Oxide Fuel Cells
Metal-supported solid oxide fuel cells have broad application prospects in distributed power generation, transportation, military, and other fields. The electrochemical performance of the cell is still a chall...
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Retraction Note: Reality of virtual damage identification based on neural networks and vibration analysis of a damaged bridge under a moving vehicle
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Correction to: Concept Design Evaluation of Sustainable Product–Service Systems: A QFD–TOPSIS Integrated Framework with Basic Uncertain Linguistic Information
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Open AccessTargeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...
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An Empirical Study on Google Research Football Multi-agent Scenarios
Few multi-agent reinforcement learning (MARL) researches on Google research football (GRF) focus on the 11-vs-11 multi-agent full-game scenario and to the best of our knowledge, no open benchmark on this scena...