350 Result(s)

Article

WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines

Collectively, the MYC family of oncoprotein transcription factors is overexpressed in more than half of all malignancies. The ability of MYC proteins to access chromatin is fundamental to their role in promoti...

Leigh A. Bumpous, Kylie C. Moe, **g Wang, Logan A. Carver… in Oncogenesis (2023)

Article

Acute heart failure with mildly reduced ejection fraction and myocardial infarction: a multi-institutional cohort study

Little research has been done on ischemic outcomes related to left ventricular ejection fraction (EF) in acute decompensated heart failure (ADHF).

Ming-Shyan Lin, Po-Chang Wang, Meng-Hung Lin, Ting-Yu Kuo… in BMC Cardiovascular Disorders (2023)

Article

Comprehensiveness of cardiac rehabilitation program in Korea: a nation-wide survey result

Cardiac rehabilitation (CR) is an essential component in secondary prevention of cardiovascular diseases. Current guidelines recommend that the program should be comprehensive including multidisciplinary behav...

Jidong Sung, Chul Kim, Jae-Young Han, Sungju Jee… in BMC Cardiovascular Disorders (2023)

Article

Lower attenuation and higher kurtosis of coronary artery calcification associated with vulnerable plaque – an agatston score propensity-matched CT radiomics study

Coronary artery calcification (CAC) burden assessed by Agatston score (AS) is currently recommended to stratify patients at risk for future acute coronary syndrome (ACS). Besides the CAC burden, the biostructu...

Eric Po-Yu Huang, Huey-Shyan Lin, Yi-Chun Chen, Yi-He Li… in BMC Cardiovascular Disorders (2023)

Article

Prediction of hypotension during the alveolar recruitment maneuver in spine surgery: a prospective observational study

Atelectasis can occur in many clinical practices. One way to prevent this complication is through the alveolar recruitment maneuver (ARM). However, hemodynamic compromise can accompany ARM. This study aims to ...

Ji Young Min, Hyun Jae Chang, Sung Jun Kim… in European Journal of Medical Research (2023)

Article

Early urate-lowering therapy in gouty arthritis with acute flares: a double-blind placebo controlled clinical trial

Gouty arthritis (GA) is a chronic systemic disease with recurrent acute monoarthritis. In a previous study, a higher incidence of acute flares was observed during the initial marked decrease in serum urate lev...

Deng-Ho Yang, Hsiang-Cheng Chen… in European Journal of Medical Research (2023)

Article

Antibody and T cell responses against wild-type and Omicron SARS-CoV-2 after third-dose BNT162b2 in adolescents

The high effectiveness of the third dose of BNT162b2 in healthy adolescents against Omicron BA.1 has been reported in some studies, but immune responses conferring this protection are not yet elucidated. In th...

**aofeng Mu, Carolyn A. Cohen, Daniel Leung… in Signal Transduction and Targeted Therapy (2022)

Article

Systemic thrombo-embolic events in a middle-aged male with Loeffler endocarditis without peripheral eosinophilia—a case report

Loeffler-endocarditis (LE) is considered a chronic restrictive cardiomyopathy and manifestation of eosinophilic myocarditis characterized by eosinophilic infiltration. LE is a rare underdiagnosed disease and a...

Mintje Bohné, Sebastian Bohnen, Hans-Christian Voigt… in BMC Cardiovascular Disorders (2022)

Article

Association between heme oxygenase one and sepsis development in patients with moderate-to-critical COVID-19: a single-center, retrospective observational study

Heme oxygenase one (HO-1) is considered a poor prognostic factor for survival in patients with severe-to-critical coronavirus disease (COVID-19), but the clinical correlation between heme catabolism biomarkers...

Hsin-Yi Chen, I-Shiang Tzeng, Kuo-Wang Tsai… in European Journal of Medical Research (2022)

Article

Effects of left atrial function on pulmonary arterial pressure in acute myocardial infarction, hypertrophic and dilated cardiomyopathy

To investigate the differential contribution of the left atrial (LA) function and left ventricular (LV) fibrosis to pulmonary arterial systolic pressure (PASP) in hypertrophic cardiomyopathy (HCM), dilated car...

Minjeong Kim, Hyemoon Chung, In-Soo Kim, Chul Hwan Park… in BMC Cardiovascular Disorders (2022)

Article

Atrial-His bundle pacing in fulminant myocarditis with ventricular arrhythmia: a case report

Fulminant myocarditis is a clinical syndrome associated with threatening dysrhythmia which temporary pacemaker can be used for life-saving support. As a method of physiological pacing, His bundle pacing (HBP) ...

Limeng Jiang, Liangguo Wang, Chuhuan Zhao, ** Zhou… in BMC Cardiovascular Disorders (2022)

Article

Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein

Hepatocellular carcinoma (HCC) accounts for 90% of primary liver cancer, the third leading cause of cancer-associated death worldwide. With the increasing prevalence of metabolic conditions, non-alcoholic fatt...

**n Tracy Liu, Long Hoa Chung, Da Liu, **biao Chen, Yu Huang… in Oncogenesis (2022)

Article

A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure

Therapy-related myeloid neoplasm (tMN) is considered a direct consequence of DNA damage in hematopoietic stem cells. Despite increasing recognition that altered stroma can also drive leukemogenesis, the functi...

Monika M. Kutyna, Chung Hoow Kok, Yoon Lim, Elizabeth Ngoc Hoa Tran… in Leukemia (2022)

Article

Shorter duration of protection and lower geometric mean titers against A/H3N2 antigen of the quadrivalent influenza vaccine in children post-allogeneic hematopoietic stem cell transplantation

Kyu Ri Kang, Ye Ji Kim, Moon Bae Ahn, Hyun Mi Kang… in Bone Marrow Transplantation (2022)

Article

Fibroblast growth factor 21 is associated with widening QRS complex and prolonged corrected QT interval in patients with stable angina

Fibroblast growth factor 21 (FGF21) is produced by cardiac cells, may acts in an autocrine manner, and was suggested to has a cardioprotective role in atherosclerosis. Wide QRS complex and heart rate-corrected...

Wei-Chin Hung, Teng-Hung Yu, Chao-** Wang, Chia-Chang Hsu… in BMC Cardiovascular Disorders (2022)