21 Result(s)

Chapter and Conference Paper

Site-Directed Mutagenesis of VKORC1, the Target Protein of Coumarin-Type Anticoagulants

Natural and site-directed mutagenesis experiments are important tools for studying the role of individual amino acids of the VKORCl protein and their involvement in the binding sites for the substrate vitamin ...

S. Rost, A. Fregin, M. Hünerberg, C. R. Müller, J. Oldenburg in 35^th Hemophilia Symposium (2006)