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Article
Slow dynamics of n-butoxyethanol–water mixture by neutron spin echo technique
We have measured the dynamics of n-buoxyethanol–water mixture of alcohol mole fraction 0.09 by using a neutron spin echo (NSE) technique at 8, 25, and 37 °C, below a lower critical solution temperature (LCST) of ...
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Article
Neutron spin echo studies of the effects of temperature and pressure in a ternary microemulsion
In order to clarify the self-assembling mechanisms in complex fluids involving amphiphiles, we have investigated dynamic features of amphiphilic membranes and droplets at high temperature and at high pressure ...
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Article
Expression of paraoxonase isoform did not confer protection from acute sarin poisoning in the Tokyo subway terrorist attack
We previously reported the polymorphism of the high density lipoprotein-associated enzyme paraoxonase (PON1), in the 10 sarin poisoning victims in the Tokyo subway terrorist attack. Arg192 PON1, which has low sa...
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Article
Hydrodynamic interactions in the structural fluctuation of a ternary amphiphilic system C12E5/water/ n-octane
Dynamical fluctuations of microemulsion and lamellar structures in a ternary amphiphilic system C12E 5/water/n-octane are studied by means of neutron spin echo spectrometry. The decay rate of the time correlation...
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Article
Open AccessInhibition of erythropoietin signalling destroys xenografts of ovarian and uterine cancers in nude mice
We have recently shown that malignant tumours from the ovary and uterus expressed erythropoietin (Epo) and its receptor (EpoR), and that deprivation of Epo signal in tumour blocks induced death of malignant ce...
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Article
Mutation screening of phenylketonuria in the Far East of Russia
We analyzed mutant genotypes at the human phenylalanine hydroxylase (PAH) locus among phenylketonuria (PKU) patients in the Far East of Russia. A total of 60 variant alleles from 30 PKU families were analyzed...
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Article
Apraxia of speech associated with an infarct in the precentral gyrus of the insula
It has been postulated that the precentral gyrus in the left insula is responsible for co-ordination of speech. We report a paitent with this disturbance who showed an acute infarct limited to this region.
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Article
Does the sequence of onset of rigor mortis depend on the proportion of muscle fibre types and on intra-muscular glycogen content?
We examined the postmortem changes in the levels of ATP, glycogen and lactic acid in two masticatory muscles and three leg muscles of rats. The proportion of fibre types of the muscles was determined with NIH...
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Article
Expressions of four major protein Ser/Thr phosphatases in human primary leukemic cells
Activity and expression of four major protein serine/threonine (Ser/Thr) phosphatases, protein phosphatase type 1 (PP1), protein phosphatase type 2A (PP2A), protein phosphatase type 2B (PP2B) and protein phosp...
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Article
Mutation analysis of the phenylalanine hydroxylase gene and its clinical implications in two Japanese patients with non-phenylketonuria hyperphenylalaninemia
We describe a mutation analysis for the phenylalanine hydroxylase gene and the clinical outcome of two Japanese patients with non-phenylketonuria (PKU) hyperphenylalaninemia (serum phenylalanine level below 6...
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Article
Expression of phosphotyrosine and SNAP-25 immunoreactivity in grumose (foamy) spheroid bodies suggests axonal regeneration
To investigate the origin of grumose (foamy) spheroid bodies (GFSB), the expression of two proteins associated with axonal regeneration, i.e., phosphotyrosine and 25-kDa synaptosomal-associated protein (SNAP-...
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Article
Connatal Pelizaeus-Merzbacher disease: A missense mutation in exon 4 of the proteolipid protein (PLP) gene
We investigated the proteolipid protein (PLP) gene in two brothers in a Japanese family with a connatal form of Pelizaeus-Merzbacher disease (PMD). Direct sequencing of the PLP gene revealed an A-to-T transition...
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Article
Decrease of protein kinase C in the spinal motor neurons of amyotrophic lateral sclerosis
The expression of protein kinase C (PKC), a calcium- and phospholipid-dependent signaling molecule, was studied immunohistochemically in the spinal motor neurons of cases of sporadic amyotrophic lateral scler...
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Article
Linkage map** of rat Rb1 gene on Chromosome 15
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Article
Carbon monoxide oxidation on (Mg6−x Al x )MnO8 (0⩽x⩽0.6)
Murdochite-type (Mg6−x Al x )MnOm8 (0⩽x⩽0.6) was synthesized at low temperature (700 °C) with the sol-gel process. The specific surface area, crystallite size, catalytic activit...
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Article
Linkage map** of the rat Tp53 gene on Chromosome 10
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Article
cDNA cloning of the rat APC gene and assignment to Chromosome 18
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Article
Genetic map** of the RET protooncogene on rat Chromosome 4
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Article
Construction of a phylogenetic tree for inbred strains of rat by arbitrarily primed polymerase chain reaction (AP-PCR)
We constructed a tentative genealogic tree of 13 inbred rat strains using genetic markers identified by the AP-PCR (Arbitrarily Primed Polymerase Chain Reaction) technique, which consists of PCR amplification ...
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Article
Surface characterization of (La1−x Sr x )MnO3 synthesized using a sol-gel process and solid-state reaction