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Article
Open AccessASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway
Extracellular acid can have important effects on cancer cells. Acid-sensing ion channels (ASICs), which emerged as key receptors for extracellular acidic pH, are differently expressed during various diseases a...
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Article
Streptomyces xinjiangensis sp. nov., an actinomycete isolated from Lop Nur region
A novel actinobacterial strain, designated LPA192T, was isolated from a soil sample collected from Lop Nur, **njiang Uygur Autonomous Region, Northwest China. A polyphasic approach was used to investigate the tax...
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Article
Phylogenetic analysis of Leymus (Poaceae: Triticeae) based on Random Amplified Polymorphic DNA
To investigate the Ns genome donor of Leymus and to elucidate the origin of Xm genome of Leymus, Random Amplified Polymorphic DNA (RAPD) markers were used to analyze 13 Leymus accessions, together with 14 taxa fr...
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Article
Phylogenetic relationships and Y genome origin in Kengyilia (Triticeae: Poaceae) based on single copy gene DMC1
To investigate the phylogenetic relationships among Kengyilia and related diploid genera, the genome donor of Kengyilia, and the evolutionary history of polyploid Kengyilia species, disrupted meiotic cDNA1 (DMC1)...
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Article
Detection of Vulnerable Atherosclerotic Plaques in Experimental Atherosclerosis with the USPIO-Enhanced MRI
This study’s goal was to assess the diagnostic value of the USPIO-(ultra-small superparamagnetic iron oxide) enhanced magnetic resonance imaging (MRI) in detection of vulnerable atherosclerotic plaques in abdo...
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Article
Phylogenetic relationships among Elymus and related diploid genera (Triticeae: Poaceae) based on nuclear rDNA ITS sequences
To investigate the phylogenetic relationships among Elymus and related diploid genera, the genome donor of Elymus, and the evolutionary history of polyploid Elymus species, nuclear ribosomal internal transcribed ...
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Article
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
The RAS–ERK pathway is known to play a pivotal role in differentiation, proliferation and tumour progression. Here, we show that Erk downregulates Forkhead box O 3a (FOXO3a) by directly interacting with and ph...