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Article
Top Electrode Area Dependence on Displacement Property of Lead Zirconate Titanate Films Prepared by Chemical Solution Deposition Process
Effects on ferroelectric and piezoelectric properties of top-electrode diameter variance from 80 to 8 μm were investigated using an AFM probing system connected with a ferroelectric test system with bipolar an...
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Article
Piezoelectric property investigation for sol-gel derived Bi4Ti3O12 thick films
Strongly (117)-oriented Bi4Ti3O12 (BIT) thin (300 nm in thickness) and thick (900 nm in thickness) films were successfully synthesized from chemical solution and the piezoelectric and ferrelectric properties were...
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Article
Fabrication of Lead Zirconate Titanate Thick Film Disks for Micro Transducer Devices
A combination of the preparation techniques for the ferroelectric films and the micro machining of Si is considered to be an effective way to fabricate microelectromechanical systems (MEMS), such as piezoelect...
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Article
Ferro- and piezoelectric properties of Bi4−xPrxTi3O12 polycrystalline thick films with Ps-vector orientation
To reveal the complete performance of intrinsic ferroelectriciy-related properties in single crystalline bismuth-layer-structured displacive ferroelectrics in film form on Si, the crucial roles of both orienta...
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Article
Thymic Involution Correlates with Severe Ulcerative Colitis Induced by Oral Administration of Dextran Sulphate Sodium in C57BL/6 Mice but not in BALB/c Mice
There is accumulating evidence to support the interactions between psychological stress and inflammatory bowel disease (IBD). In order to elucidate the relationship between psycoimmunological stress and IBD, w...
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Age-Dependent Changes in Dopaminergic Neuron Firing Patterns in Substantia Nigra Pars Compacta
Dopaminergic neurons in the substantia nigra pars compacta modulate complex motor control. Nigral dopaminergic neurons exhibit three different firing patterns in vivo: a pacemaker mode, a random mode, and a bu...
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Article
Isolation of a novel cell wall architecture mutant of rice with defective Arabidopsis COBL4 ortholog BC1 required for regulated deposition of secondary cell wall components
The plant secondary cell wall is a highly ordered structure composed of various polysaccharides, phenolic components and proteins. Its coordinated regulation of a number of complex metabolic pathways and assem...
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Article
GADD34 suppresses wound healing by upregulating expression of myosin IIA
Wound healing consists of sequential steps of tissue repair, and cell migration is particularly important. In order to analyze the potential function of growth arrest and DNA damage inducible protein 34 (GADD3...
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Article
Open AccessTherapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells
Induced pluripotent stem (iPS) cells are the novel stem cell population induced from somatic cells. It is anticipated that iPS will be used in the expanding field of regenerative medicine. Here, we investigate...
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Aging in the Mouse and Perspectives of Rejuvenation Through Induced Pluripotent Stem Cells (iPSCs)
The mouse is a perfect model to study aging in mammals. It has a relatively short life span and genetic manipulations in this species are well established. Most interestingly, the mouse is a fantastic tool to ...
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Article
Autophagic activity in thymus and liver during aging
Impaired or deficient autophagy is believed to cause or contribute to aging, as well as several age-related pathologies. Thymic epithelial cells had a high constitutive level of autophagy. The autophagic proce...
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Article
Open AccessiPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis
Angiogenic cell therapy represents a novel strategy for ischemic diseases, but some patients show poor responses. We investigated the therapeutic potential of an induced pluripotent stem (iPS) cell sheet creat...
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Article
Open AccessGADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
Autophagy is a common physiological function in all eukaryotes. The process is induced by depletion of nutrients including amino acids. GADD34 is expressed following DNA damage, ER stresses and amino acid depr...
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Article
Recruitment of Gr1+CD11b+F4/80+ Population in the Bone Marrow and Spleen by Irradiation-Induced Pulmonary Damage
Radiation-induced lung injury is a kind of sterile inflammation, which may lead to morbidity and mortality. The mechanism by which ionizing radiation activate the immune system is not well understood. In the p...
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Article
Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model
Growth arrest and DNA damage-inducible protein (GADD34/Ppp1r15a) is induced by various stimuli including DNA damage and ER stress. DNA damage and oncogene activation, accompanied by tumor-specific DNA repair d...
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Article
Open AccessEffects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice
Growth arrest and DNA damage-inducible protein 34 (GADD34/Ppp1r15a) is a family of GADD proteins that are induced by DNA damage. GADD34 protein has been suggested to regulate inflammation or host defense syste...
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Article
Erratum to: Recruitment of Gr1+CD11b+F4/80+Population in the Bone Marrow and Spleen by Irradiation-Induced Pulmonary Damage
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Article
Open AccessVancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils
Inflammatory bowel disease confers an increased risk of develo** colitis-associated colon cancer (CAC). During the active colitis or develo** tumor stage, commensal bacteria show dynamic translocation. How...
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Article
Open AccessEsophageal submucosal hematoma developed after endovascular surgery for unruptured cerebral aneurysm under general anesthesia: a case report
Esophageal submucosal hematoma is a rare complication after endovascular surgery. We report a case of an esophageal submucosal hematoma which may have been caused by rigorous cough during extubation.
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Article
Mediating Factors Between Parental Socioeconomic Status and Small for Gestational Age in Infants: Results from the Hokkaido Study on Environment and Children’s Health
Previous studies indicated a significant association between small for gestational age (SGA) in infants and their parents' socioeconomic status (SES). Thus, this study aimed to examine if parental factors, suc...
