432 Result(s)

Article

Trends in incidence and mortality of nasopharyngeal carcinoma over a 20–25 year period (1978/1983–2002) in Sihui and Cangwu counties in southern China

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world but is common in southern China. A recent report from the Hong Kong Cancer Registry, a high-risk area for NPC in southern China, s...

Wei-Hua Jia, Qi-Hong Huang, Jian Liao, Weimin Ye, YY Shugart, Qing Liu… in BMC Cancer (2006)

Article

The synergistic inhibitory effect of somatostatin-doxorubicin co-treatment on gallbladder carcinoma

Gallbladder cancer is the most common billiary tract malignancy and carries a very poor prognosis. Somatostatin was recently shown to play an important role in the development of various tumors. In the current...

Ji-Yu Li, Zhi-Wei Quan, Qiang Zhang, Jian-Wen Liu in BMC Cancer (2007)

Article

In silico analysis and verification of S100 gene expression in gastric cancer

The S100 protein family comprises 22 members whose protein sequences encompass at least one EF-hand Ca²⁺ binding motif. They were involved in the regulation of a number of cellular processes such as cell cycle pr...

Ji Liu, Xue Li, Guang-Long Dong, Hong-Wei Zhang, Dong-Li Chen, Jian-Jun Du… in BMC Cancer (2008)

Article

Expression of Bmi-1 is a prognostic marker in bladder cancer

The molecular mechanisms of the development and progression of bladder cancer are poorly understood. The objective of this study was to analyze the expression of Bmi-1 protein and its clinical significance in ...

Zi-Ke Qin, Jian-An Yang, Yun-lin Ye, **ng Zhang, Li-Hua Xu, Fang-Jian Zhou… in BMC Cancer (2009)

Article

Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model

Liver cancr is a heterogeneous disease in terms of etiology, biologic and clinical behavior. Very little is known about how many genes concur at the molecular level of tumor development, progression and aggres...

Yue-Fang Liu, Bin-Shan Zha, Hui-Lin Zhang… in Journal of Experimental & Clinical Cancer … (2009)

Article

Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells

Activator protein 2 gamma (AP-2γ) is a member of the transcription factor activator protein-2 (AP-2) family, which is developmentally regulated and plays a role in human neoplasia. AP-2γ has been found to be o...

He Ailan, **ao **angwen, Ren Daolong, Gan Lu, Ding **aofeng, Qiao **… in BMC Cancer (2009)

Article

Maintenance of Sorafenib following combined therapy of three-dimensional conformal radiation therapy/intensity-modulated radiation therapy and transcatheter arterial chemoembolization in patients with locally advanced hepatocellular carcinoma: a phase I/II study

Three-dimensional conformal radiation therapy (3DCRT)/intensity-modulated radiation therapy (IMRT) combined with or without transcatheter arterial chemoembolization (TACE) for locally advanced hepatocellular c...

Jian-Dong Zhao, ** Liu, Zhi-Gang Ren, Ke Gu, Zhen-Hua Zhou… in Radiation Oncology (2010)

Article

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor α by inhibiting NF-κB signaling pathway

Tumor necrosis factor alpha (TNFα) has been used to treat certain tumors in clinic trials. However, the curative effect of TNFα has been undermined by the induced-NF-κB activation in many types of tumor. Masli...

Chenghai Li, Zhengfeng Yang, Chunyan Zhai, Wenwei Qiu, Dali Li… in Molecular Cancer (2010)

Article

Cyclin K and cyclin D1b are oncogenic in myeloma cells

Aberrant expression of cyclin D1 is a common feature in multiple myeloma (MM) and always associated with mantle cell lymphoma (MCL). CCND1 gene is alternatively spliced to produce two cyclin D1 mRNA isoforms whic...

Véronique Marsaud, Guergana Tchakarska, Geoffroy Andrieux… in Molecular Cancer (2010)

Article

Health-related quality of life in glioma patients in China

Health-related quality of life (HRQOL) has been increasingly emphasized in cancer patients. There are no reports comparing baseline HRQOL of different subgroups of glioma patients prior to surgery.

**-xiang Cheng, Bo-lin Liu, **ang Zhang, Wei Lin, Yong-qiang Zhang… in BMC Cancer (2010)

Article

Synuclein gamma predicts poor clinical outcome in colon cancer with normal levels of carcinoembryonic antigen

Synuclein gamma (SNCG), initially identified as a breast cancer specific gene, is aberrantly expressed in many different malignant tumors but rarely expressed in matched nonneoplastic adjacent tissues. In this...

Caiyun Liu, Bin Dong, Ai** Lu, Like Qu, **aofang **ng, Lin Meng, Jian Wu… in BMC Cancer (2010)

Article

Prognostic significance and therapeutic implications of centromere protein F expression in human nasopharyngeal carcinoma

Our recent cDNA microarray data showed that centromere protein F (CENP-F) is significantly upregulated in primary cultured nasopharyngeal carcinoma (NPC) tumor cells compared with normal nasopharyngeal epithel...

**g-Yan Cao, Li Liu, Shu-Peng Chen, **ng Zhang, Yan-Jun Mi… in Molecular Cancer (2010)

Article

Estrogen receptor α (ERα) mediates 17β-estradiol (E2)-activated expression of HBO1

HBO1 (histone acetyltransferase binding to ORC1) is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. However, the biological role and underlying mechanism of HBO1 in bre...

Wen-zhong Wang, Hai-ou Liu, Yi-hong Wu… in Journal of Experimental & Clinical Cancer … (2010)

Article

Role of 14-3-3σ in poor prognosis and in radiation and drug resistance of human pancreatic cancers

Pancreatic cancer is the fourth leading cause of death in the US. Unlike other solid tumors such as testicular cancer which are now curable, more than 90% of pancreatic cancer patients die due to lack of respo...

Zhaomin Li, Zizheng Dong, David Myer, Michele Yip-Schneider, Jianguo Liu… in BMC Cancer (2010)

Article

Addendum: Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection

Hon-Ming Lam, Xun Xu, **n Liu, Wenbin Chen, Guohua Yang, Fuk-Ling Wong… in Nature Genetics (2011)

Article

Continuous and low-energy ¹²⁵I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth

Iodine 125 (¹²⁵I) seed irradiation is an effective treatment for unresectable pancreatic cancers. However, the radiobiological mechanisms underlying brachytherapy remain unclear. Therefore, we investigated the in...

Jian-xia Ma, Zhen-dong **, Pei-ren Si… in Journal of Experimental & Clinical Cancer … (2011)

Article

5-allyl-7-gen-difluoromethoxychrysin enhances TRAIL-induced apoptosis in human lung carcinoma A549 cells

5-allyl-7-gen-difluoromethoxychrysin (AFMC) is a novel synthetic analogue of chrysin that has been reported to inhibit proliferation in various cancer cell lines. Tumor necrosis factor-related apoptosis-induci...

Zhao-Hui **e, Mei-Fang Quan, Fei Liu, Jian-Guo Cao, Jian-Song Zhang in BMC Cancer (2011)

Article

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

Tumor-associated macrophages (TAMs) are alternatively activated cells induced by interleukin-4 (IL-4)-releasing CD4⁺ T cells. TAMs promote breast cancer invasion and metastasis; however, the mechanisms underlying...

Mei Yang, **gqi Chen, Fang Su, Bin Yu, Fengxi Su, Ling Lin, Yujie Liu… in Molecular Cancer (2011)

Article

Clinical application of CT-guided ¹²⁵I seed interstitial implantation for local recurrent rectal carcinoma

The present study aimed to explore the safety profile and clinical efficacy of CT-guided radioactive seed implantation in treating local recurrent rectal carcinoma.

Zhongmin Wang, Jian Lu, Lin Liu, Tao Liu, Kemin Chen, Fenju Liu… in Radiation Oncology (2011)

Article

ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma

ARTEMIN (ARTN) is an estrogen regulated growth factor, the expression of which promotes resistance to antiestrogen therapies and predicts poorer survival outcome of patients with estrogen receptor (ER) positiv...

Arindam Banerjee, Zheng-Sheng Wu, PengXu Qian, Jian Kang… in Breast Cancer Research (2011)