57 Result(s)
within
Javier Herrero
English
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Chapter and Conference Paper
Using Perceptrons for Supervised Classification of DNA Microarray Samples: Obtaining the Optimal Level of Information and Finding Differentially Expressed Genes
The success of the application of neural networks to DNA microarray data comes from their efficiency in dealing with noisy data. Here we describe a combined approach that provides, at the same time, an accurat...
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Chapter
Supervised Neural Networks for Clustering Conditions in DNA Array Data After Reducing Noise by Clustering Gene Expression Profiles
In this paper we compare various applications of supervised and unsupervised neural networks to the analysis of the gene expression profiles produced using DNA microarrays. In particular we are interested in t...
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Article
Using a Genetic Algorithm and a Perceptron for Feature Selection and Supervised Class Learning in DNA Microarray Data
Class prediction and feature selection is keyin the context of diagnostic applications ofDNA microarrays. Microarray data is noisy andtypically composed of a low number of samplesand a large number of genes. P...
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Article
Improved Class Prediction in DNA Microarray Gene Expression Data by Unsupervised Reduction of the Dimensionality followed by Supervised Learning with a Perceptron
This manuscript describes a combined approach of unsupervised clustering followed by supervised learning that provides an efficient classification of conditions in DNA array gene expression experiments (differ...
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Chapter and Conference Paper
Salinibacter Ruber: Genomics and Biogeography
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Article
TranscriptSNPView: a genome-wide catalog of mouse coding variation
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Article
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
An inability to estimate absolute DNA methylation levels has slowed progress in understanding the role of this epigenetic modification in health and disease. Down et al. describe an algorithm for analyzing methyl...
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Article
Compative robustness of six tests in repeated measures designs with specified departures from sphericity
In this article we examine the behaviour of six univariate statistics for analyzing the data of a Split-plot factorial design. Except for the univariate analysis of variance, which assumes that the dispersion ...
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Article
Open AccesseHive: An Artificial Intelligence workflow system for genomic analysis
The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two weeks are allocated to generate all the genomi...
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Article
Open AccessComparative and demographic analysis of orang-utan genomes
The genome of the Southeast Asian great ape or orang-utan has been sequenced — specifically a draft assembly of a Sumatran female individual and short-read sequence data from five further Sumatran and five Bor...
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Article
Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses
A response to 2x genomes - depth does matter by MC Milinkovitch, R Helaers, E Depiereux, AC Tzika and T Gabaldón. Genome Biol2010, 11:R16.
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Article
Open AccessGenome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and the first representative of the iconic hop** mammals that symbolize Australia to be sequenced...
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Article
Open AccessA high-resolution map of human evolutionary constraint using 29 mammals
The comparison of related genomes has emerged as a powerful lens for genome interpretation. Here we report the sequencing and comparative analysis of 29 eutherian genomes. We confirm that at least 5.5% of the ...
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Article
Erratum to: Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
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Article
Open AccessInsights into hominid evolution from the gorilla genome sequence
Gorillas are humans’ closest living relatives after chimpanzees, and are of comparable importance for the study of human origins and evolution. Here we present the assembly and analysis of a genome sequence fo...
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Article
Open AccessAnalysis of variation at transcription factor binding sites in Drosophila and humans
Advances in sequencing technology have boosted population genomics and made it possible to map the positions of transcription factor binding sites (TFBSs) with high precision. Here we investigate TFBS variabil...
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Chapter and Conference Paper
Supervised Learning Modelization and Segmentation of Cardiac Scar in Delayed Enhanced MRI
Delayed Enhancement Magnetic Resonance Imaging can be used to non-invasively differentiate viable from non-viable myocardium within the Left Ventricle in patients suffering from myocardial diseases. Automated ...
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Article
Open AccessThe zebrafish reference genome sequence and its relationship to the human genome
A high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that...
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Article
Open AccessSequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Jeramiah Smith, Weiming Li and colleagues report the whole-genome sequence of the sea lamprey, Petromyzon marinus, representing a vertebrate lineage diverged from humans ~500 million years ago. Their analyses def...
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Article
Open AccessThe draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan
Naoki Irie and colleagues report the draft genomes of the soft-shell and green sea turtles. Their genome-wide phylogenetic analysis supports the hypothesis that turtles are a sister group of crocodilians and b...
