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Supported Lipid Bilayers

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Encyclopedia of Biophysics

Synonyms

Lipid bilayer

Introduction

Supported lipid bilayers are used in many biophysical investigations as well as in analytical devices. They are mechanically stable with defined properties, and they can be interfaced with means to monitor electric, mechanical, or diffusion-related properties (“Lipid Lateral Diffusion”). Furthermore, supported lipid bilayers have been designed to exhibit well-defined shapes and curvature, which can be planar, spherical, or cylindrical depending on the nature of the support. They have been prepared as single bilayer deposits (Brian and McConnell 1984) or as stacks of lipid bilayers where only the outermost membranes are in contact with the solid support (Fig. 1) (Powers and Clark 1975). In the latter case, the mechanical alignment of the membrane in direct contact with the mechanical support is transmitted throughout the stack through the interaction between subsequent bilayers (Fig. 1e) (Aisenbrey et al. 2010). Supported lipid membranes come in many...

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Author information

Authors and Affiliations

  1. Institut de Chimie, Université de Strasbourg/CNRS, UMR7177, Strasbourg, France

    Burkhard Bechinger

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  1. Burkhard Bechinger
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Correspondence to Burkhard Bechinger .

Editor information

Editors and Affiliations

  1. University Leicester MRC Centre, Leicester, UK

    Gordon Roberts

  2. Dept Biochemistry, University of Oxford, Oxford, UK

    Anthony Watts

Section Editor information

  1. Membrane Biophysics Platform, Department of Chemistry and Institute of Chemical Biology, Imperial College London, London, UK

    John Seddon

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© 2019 European Biophysical Societies' Association (EBSA)

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Bechinger, B. (2019). Supported Lipid Bilayers. In: Roberts, G., Watts, A. (eds) Encyclopedia of Biophysics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35943-9_566-1

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  • DOI: https://doi.org/10.1007/978-3-642-35943-9_566-1

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  • Print ISBN: 978-3-642-35943-9

  • Online ISBN: 978-3-642-35943-9

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