Amnestic Disorder

  • Living reference work entry
  • First Online:
Encyclopedia of Clinical Neuropsychology
  • 733 Accesses

Short Description or Definition

Amnestic disorders are defined by a decline in explicit memory in the absence of other significant cognitive impairments and represent a deterioration from previous levels of function. The hallmark feature of classic amnestic disorders is anterograde amnesia (impairment in the ability to form new explicit memories), although retrograde amnesia (inability to remember previously learned information) can be seen, usually in a temporal gradient with recent memories affected more than earlier ones. This entry focuses on persistent, nonprogressive etiologies of amnestic disorders, excluding etiologies such as transient global amnesia, neurodegenerative conditions (e.g., Alzheimer’s disease), and psychogenic amnesias.

Categorization

Amnestic disorders can result from a variety of causes, including hypoxic/anoxic events, infections, nutritional deficiencies, and lesions such as those occurring following stroke or surgical ablation, and are associated with damage...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References and Readings

  • Bauer, R. M., Grande, L., & Valenstein, E. (2003). Amnesic disorders. In K. M. Heilman & E. Valenstein (Eds.), Clinical neuropsychology (pp. 495–573). New York: Oxford University Press.

    Google Scholar 

  • Bengtsson, M., & Godbolt, A. K. (2016). Effects of acetylcholinesterase inhibitors on cognitive function in patients with chronic traumatic brain injury: A systematic review. Journal of Rehabilitation Medicine, 5, 1–5.

    Article  Google Scholar 

  • Benke, T., Köylü, B., Delazer, M., Trinka, E., & Kemmler, G. (2005). Cholinergic treatment of amnesia following basal forebrain lesion due to aneurysm rupture – An open-label pilot study. European Journal of Neurology, 12, 791–796.

    Article  PubMed  Google Scholar 

  • Bottger, S., Prosiegel, M., Steiger, H., & Yassouridis, A. (1998). Neurobehavioral disturbances, rehabilitation outcome, and lesion site in patients after rupture and repair of anterior communicating artery aneurysm. Journal of Neurology, Neurosurgery, and Psychiatry, 65, 93–102.

    Article  PubMed  PubMed Central  Google Scholar 

  • Caine, D., & Watson, J. D. G. (2000). Neuropsychological and neuropathological sequelae of cerebral anoxia: A critical review. Journal of the International Neuropsychological Society, 6, 86–99.

    Article  PubMed  Google Scholar 

  • Corkin, S. (2002). What’s new with the amnesic patient H.M.? Nature Reviews: Neuroscience, 3, 153–160.

    Article  PubMed  Google Scholar 

  • Downes, J. J., Mayes, A. R., MacDonald, C., & Hunkin, N. M. (2002). Temporal order memory in patients with Korsakoff’s syndrome and medial temporal amnesia. Neuropsychologia, 40, 853–861.

    Article  PubMed  Google Scholar 

  • Hashimoto, R., Tanaka, Y., & Nakano, I. (2000). Amnesic confabulatory syndrome after focal basal forebrain damage. Neurology, 54, 978–980.

    Article  PubMed  Google Scholar 

  • Kopelman, M. D., Stanhope, N., & Kingsley, D. (1999). Retrograde amnesia in patients with diencephalic, temporal lobe or frontal lesions. Neuropsychologia, 37, 939–958.

    Article  PubMed  Google Scholar 

  • McKee, R. D., & Squire, L. R. (1992). Both hippocampal and diencephalic amnesia result in normal forgetting for complex visual material. Journal of Clinical and Experimental Neuropsychology, 14, 103.

    Google Scholar 

  • Osimani, A., Vakil, E., Blinder, G., Sobel, R., & Abarbanel, J. M. (2006). Basal forebrain amnesia: A case study. Cognitive and Behavioral Neurology, 19, 65–70.

    Article  PubMed  Google Scholar 

  • Scoville, W. B., & Milner, B. (1957). Loss of recent memory after bilateral hippocampal lesions. Journal of Neurology, Neurosurgery, and Psychiatry, 20, 11–21.

    Article  PubMed  PubMed Central  Google Scholar 

  • Squire, L. R. (1982). Comparisons between forms of amnesia: Some deficits are unique to Korsakoff’s syndrome. Journal of Experimental Psychology: Learning, Memory, and Cogntion, 8, 560–571.

    Google Scholar 

  • Tidswell, P., Dias, P. S., Sagar, H. J., Mayes, A. R., & Battersby, R. D. E. (1995). Cognitive outcome after aneurysm rupture: Relationship to aneurysm site and perioperative complications. Neurology, 45, 875–882.

    Article  PubMed  Google Scholar 

  • Utley, T. F. M., Ogden, J. A., Gibb, A., McGrath, N., & Anderson, N. E. (1997). The long-term neuropsychological outcome of herpes simplex encephalitis in a series of unselected survivors. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 10, 180–189.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Beth Springate .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this entry

Cite this entry

Springate, B. (2017). Amnestic Disorder. In: Kreutzer, J., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-56782-2_1105-2

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-56782-2_1105-2

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-56782-2

  • Online ISBN: 978-3-319-56782-2

  • eBook Packages: Springer Reference Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences

Publish with us

Policies and ethics

Navigation