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Congenital Malformations of the Brain: Spectrum and Causes

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Neonatology

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Abstract

Defective nervous system development results in a diverse group of diseases, ranging from major malformations that are incompatible with postnatal life to moderate or severe disabilities. Congenital malformations of the brain refer to any structural abnormality of the central nervous system (CNS), present at birth, and due to interrupted or modified CNS development during intrauterine life, whatever the etiology. The frequency of CNS malformations has been estimated to be 5–10/1000 births, found in 5–10% of stillborn infants, or early deceased neonates.

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Authors and Affiliations

  1. Department of Neonatology and Pediatric Intensive Care, Université François Rabelais and CHRU de Tours, Tours, 37000, France

    Elie Saliba

  2. Inserm U930, France, Université François Rabelais and CHRU de Tours, Tours, 37000, France

    Elie Saliba

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  1. Elie Saliba
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Editors and Affiliations

  1. Siena, Italy

    Giuseppe Buonocore

  2. Medicina della Riproduzione, Università di Siena Dipto. Pediatria, Ostetricia e, Siena, Italy

    Rodolfo Bracci

  3. Liverpool Women's Hospital Neonatal Unit, Liverpool, United Kingdom

    Michael Weindling

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Saliba, E. (2016). Congenital Malformations of the Brain: Spectrum and Causes. In: Buonocore, G., Bracci, R., Weindling, M. (eds) Neonatology. Springer, Cham. https://doi.org/10.1007/978-3-319-18159-2_271-1

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  • DOI: https://doi.org/10.1007/978-3-319-18159-2_271-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18159-2

  • Online ISBN: 978-3-319-18159-2

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