Abstract
The fine structure of the reindeer cornea in normal conditions and in spontaneous keratitis was described. There were more layers of squamous and fewer layers of polyhedral cells than in pigs, cattle and horses.
Mild cases of corneal opacity just had some swollen superficial epithelial cells.
When fully developed the keratitis had all the characteristics of an acute inflammation. Swelling or shrinking of the epithelial cells with or without degenerative nuclear changes were common. A striking alteration of the epithelial cells was the irregular appearance of the filaments which was frequently observed. In some cases there was pronounced intercellular oedema with desquamation of the superficial squamous cells and occasional neutrophils in the intercellular space. The stroma was the site of oedema, infiltration of leukocytes and vascularization.
The aetiology and pathogenesis of the disease are not yet established but experimental research on these problems is in progress.
Sammanfattning
Ultrastrukturen hos renens normala cornea och förändringarna i samband med keratit har beskrivits. Det förelåg normalt hos renen fler lager plattepitel och färre lager polyedriska celler än hos svin, nöt och häst.
I milda fall av corneal grumling iakttogs enbart några ansvällda ytliga epitelceller. Vid fullt utvecklad keratit förelåg alla karakteristika för en akut inflammation. Ansvällning eller skrumpning av epitelcellerna med eller utan degenerativa kärnförändringar förekom ofta. En påtaglig och vanlig förändring i epitelcellerna var tonofilamentens oregelbundna fördelning med ansamling i tjoka buntar. I en del fall sågs ett kraftigt intra- och intercellulärt ödem med deskvamation av de ytliga plattepitelcellerna och med enstaka neutrofiler i intercellularrummen. Stromat var säte for ödem, leukocytinfiltration och vaskularisering. Sjukdomens etiologi och patogenes är ännu ej klarlagda, men undersökningar gällande dessa problem pågår.
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Winqvist, G., Rehbinder, C. Fine Structure of the Reindeer Cornea in Normal Conditions and in Keratitis. Acta Vet Scand 14, 292–300 (1973). https://doi.org/10.1186/BF03547447
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DOI: https://doi.org/10.1186/BF03547447