Abstract
There are global trends for develo** green and sustainable technologies in food processing, due to the growing awareness of the importance of environmental preservation and the consumer demand for natural high-value food products. Meeting these particular requirements, supercritical carbon dioxide (SC-CO2) has emerged as an innovative and promising technology for the processing of food ingredients and products. Over the last two decades, applications of SC-CO2 have attracted much attention and made great advancements at both laboratory and industrial level. These advances include the extraction of target bioactive compounds from various food matrices, microencapsulation, or extrusion to produce fine particles, and the inactivation of pathogenic and spoilage microorganisms and endogenous enzymes for food preservation. An example of successfully applying SC-CO2 at the commercial level is the decaffeination of coffee. In this article, an overview of the SC-CO2 applications in food processing including extraction, transformation, preservation, and drying are presented. For each application category, principles, processing parameters, characteristics, and latest applications are critically reviewed.
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References
Misra NN, Koubaa M, Roohinejad S, Juliano P, Alpas H, Inacio RS, Saraiva JA, Barba FJ (2017) Landmarks in the historical development of twenty first century food processing technologies. Food Res Int 97:318–339
Zhang ZH, Wang LH, Zeng XA, Han Z, Brennan CS (2019) Non-thermal technologies and its current and future application in the food industry: A review. Int J Food Sci Technol 54(1):1–13
Knez Z, Markocic E, Leitgeb M, Primozic M, Hrncic MK, Skerget M (2014) Industrial applications of supercritical fluids: A review. Energy 77:235–243
Palmer MV, Ting SST (1995) Applications for supercritical-fluid technology in food-processing. Food Chem 52(4):345–352
Raventos M, Duarte S, Alarcon R (2002) Application and possibilities of supercritical CO2 extraction in food processing industry: an overview. Food Sci Technol Int 8(5):269–284
Essien SO, Young B, Baroutian S (2020) Recent advances in subcritical water and supercritical carbon dioxide extraction of bioactive compounds from plant materials. Trends Food Sci Technol 97:156–169
Pereira CG, Meireles MAA (2010) Supercritical fluid extraction of bioactive compounds: fundamentals, applications and economic perspectives. Food Bioprocess Technol 3(3):340–372
Perrut M, Perrut V (2019) Supercritical fluid applications in the food industry. Academic Press Ltd-Elsevier Science Ltd, London
Silva EK, Meireles MAA, Saldana MDA (2020) Supercritical carbon dioxide technology: a promising technique for the non-thermal processing of freshly fruit and vegetable juices. Trends Food Sci Technol 97:381–390
Smigic N, Djekic I, Tomic N, Udovicki B, Rajkovic A (2019) The potential of foods treated with supercritical carbon dioxide (sc-CO2) as novel foods. Br Food J 121(3):815–834
Lack E, Seidlitz H (1993) Commercial scale decaffeination of coffee and tea using supercritical CO2, in: King MB, Bott TR (Eds.), Extraction of Natural Products Using Near-Critical Solvents. Springer, Dordrecht
Bubalo MC, Vidovic S, Redovnikovic IR, Jokic S (2018) New perspective in extraction of plant biologically active compounds by green solvents. Food Bioprod Process 109:52–73
Gil-Chavez GJ, Villa JA, Ayala-Zavala JF, Heredia JB, Sepulveda D, Yahia EM, Gonzalez-Aguilar GA (2013) Technologies for extraction and production of bioactive compounds to be used as nutraceuticals and food ingredients: An overview. Compr Rev Food Sci Food Saf 12(1):5–23
Herrero M, Mendiola JA, Cifuentes A, Ibanez E (2010) Supercritical fluid extraction: recent advances and applications. J Chromatogr A 1217(16):2495–2511
Wijngaard H, Hossain MB, Rai DK, Brunton N (2012) Techniques to extract bioactive compounds from food by-products of plant origin. Food Res Int 46(2):505–513
Gomes MTMS, Santos DT, Meireles MAA (2012) Trends in particle formation of bioactive compounds using supercritical fluids and nanoemulsions. Food and Public Health 2(5):142–152
Vardanega R, Nathia-Neves G, Veggi PC, Meireles MAA (2019) 3 Supercritical fluid processing and extraction of food. Green Food Processing Techniques: Preservation, Transformation and Extraction: 57
Rodriguez-Meizoso I, Plaza M (2015) Particle Formation of Food Ingredients by Supercritical Fluid Technology, in: Fornari T, Stateva RP (Eds.), High pressure fluid technology for green food processing. Springer, New York
Garcia-Gonzalez L, Geeraerd AH, Spilimbergo S, Elst K, Van Ginneken L, Debevere J, Van Impe JF, Devlieghere F (2007) High pressure carbon dioxide inactivation of microorganisms in foods: The past, the present and the future. Int J Food Microbiol 117(1):1–28
Hu WF, Zhou LY, Xu ZZ, Zhang Y, Liao XJ (2013) Enzyme Inactivation in Food Processing using High Pressure Carbon Dioxide Technology. Crit Rev Food Sci Nutr 53(2):145–161
Spilimbergo S, Bertucco A, Lauro F, Bertoloni G (2003) Inactivation of Bacillus subtilis spores by supercritical CO2 treatment. Innovative Food Sci Emerging Technol 4(2):161–165
Bourdoux S, Rajkovic A, De Sutter S, Vermeulen A, Spilimbergo S, Zambon A, Hofland G, Uyttendaele M, Devlieghere F (2018) Inactivation of Salmonella, Listeria monocytogenes and Escherichia coli O157:H7 inoculated on coriander by freeze-drying and supercritical CO2 drying. Innovative Food Sci Emerging Technol 47:180–186
Chemat F, Rombaut N, Meullemiestre A, Turk M, Perino S, Fabiano-Tixier AS, Abert-Vian M (2017) Review of green food processing techniques. Preservation, transformation, and extraction. Innovative Food Sci Emerging Technol 41:357–377
Clarke CJ, Tu WC, Levers O, Brohl A, Hallett JP (2018) Green and sustainable solvents in chemical processes. Chem Rev 118(2):747–800
Belwal T, Ezzat SM, Rastrelli L, Bhatt ID, Daglia M, Baldi A, Devkota HP, Orhan IE, Patra JK, Das G, Anandharamakrishnan C, Gomez-Gomez L, Nabavi SF, Nabavi SM, Atanasov AG (2018) A critical analysis of extraction techniques used for botanicals: Trends, priorities, industrial uses and optimization strategies. Trac-Trends Anal Chem 100:82–102
Chemat F, Vian MA, Cravotto G (2012) Green extraction of natural products: Concept and principles. Int J Mol Sci 13(7):8615–8627
de Melo MMR, Silvestre AJD, Silva CM (2014) Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology. J Supercrit Fluids 92:115–176
Peng WL, Mohd-Nasir H, Setapar SHM, Ahmad A, Lokhat D (2020) Optimization of process variables using response surface methodology for tocopherol extraction from Roselle seed oil by supercritical carbon dioxide. Ind Crops Prod 143
Sharif KM, Rahman MM, Azmir J, Mohamed A, Jahurul MHA, Sahena F, Zaidul ISM (2014) Experimental design of supercritical fluid extraction—a review. J Food Eng 124:105–116
Brunner G (2005) Supercritical fluids: Technology and application to food processing. J Food Eng 67(1–2):21–33
Yousefi M, Rahimi-Nasrabadi M, Pourmortazavi SM, Wysokowski M, Jesionowski T, Ehrlich H, Mirsadeghi S (2019) Supercritical fluid extraction of essential oils. Trac-Trends Anal Chem 118:182–193
Tongnuanchan P, Benjakul S (2014) Essential oils: Extraction, bioactivities, and their uses for food preservation. J Food Sci 79(7):R1231–R1249
El Asbahani A, Miladi K, Badri W, Sala M, Addi EHA, Casabianca H, El Mousadik A, Hartmann D, Jilale A, Renaud FNR, Elaissari A (2015) Essential oils: From extraction to encapsulation. Int J Pharm 483(1–2):220–243
de Oliveira MS, da Cruz JN, Silva SG, da Costa WA, de Sousa SHB, Bezerra FWF, Teixeira E, da Silva NJN, de Aguiar Andrade EH, Neto AMdJC (2019) Phytochemical profile, antioxidant activity, inhibition of acetylcholinesterase and interaction mechanism of the major components of the Piper divaricatum essential oil obtained by supercritical CO2. J Supercrit Fluids 145:74–84
Majdoub S, El Mokni R, Muradalievich AA, Piras A, Porcedda S, Hammami S (2019) Effect of pressure variation on the efficiency of supercritical fluid extraction of wild carrot (Daucus carota subsp. maritimus) extracts. J Chromatogr B 1125:121713
Sodeifian G, Sajadian SA (2017) Investigation of essential oil extraction and antioxidant activity of Echinophora platyloba DC. using supercritical carbon dioxide. J Supercrit Fluids 121:52–62
Fornari T, Vicente G, Vázquez E, García-Risco MR, Reglero G (2012) Isolation of essential oil from different plants and herbs by supercritical fluid extraction. J Chromatogr A 1250:34–48
Pourmortazavi SM, Hajimirsadeghi SS (2007) Supercritical fluid extraction in plant essential and volatile oil analysis. J Chromatogr A 1163(1–2):2–24
Gwee YL, Yusup S, Tan RR, Yiin CL (2020) Techno-economic and life-cycle assessment of volatile oil extracted from Aquilaria sinensis using supercritical carbon dioxide. J CO2 Util 38:158–167
Moncada J, Tamayo JA, Cardona CA (2016) Techno-economic and environmental assessment of essential oil extraction from Oregano (Origanum vulgare) and Rosemary (Rosmarinus officinalis) in Colombia. J Cleaner Prod 112:172–181
Lima M, de Sousa CP, Fernandez-Prada C, Harel J, Dubreuil J, de Souza E (2019) A review of the current evidence of fruit phenolic compounds as potential antimicrobials against pathogenic bacteria. Microb Pathog 130:259–270
Salehi B, Vlaisavljevic S, Adetunji CO, Adetunji JB, Kregiel D, Antolak H, Pawlikowska E, Uprety Y, Mileski KS, Devkota HP (2019) Plants of the genus Vitis: Phenolic compounds, anticancer properties and clinical relevance. Trends Food Sci Technol 91:362–379
Wu G, Chang C, Hong C, Zhang H, Huang J, ** Q, Wang X (2019) Phenolic compounds as stabilizers of oils and antioxidative mechanisms under frying conditions: A comprehensive review. Trends Food Sci Technol 92:33–45
Arshadi M, Attard TM, Lukasik RM, Brncic M, da Costa Lopes AM, Finell M, Geladi P, Gerschenson LN, Gogus F, Herrero M (2016) Pre-treatment and extraction techniques for recovery of added value compounds from wastes throughout the agri-food chain. Green Chem 18(23):6160–6204
Sato T, Ikeya Y, Adachi S, Yagasaki K, Nihei K, Itoh N (2019) Extraction of strawberry leaves with supercritical carbon dioxide and entrainers: Antioxidant capacity, total phenolic content, and inhibitory effect on uric acid production of the extract. Food Bioprod Process 117:160–169
Valadez-Carmona L, Ortiz-Moreno A, Ceballos-Reyes G, Mendiola JA, Ibanez E (2018) Valorization of cacao pod husk through supercritical fluid extraction of phenolic compounds. J Supercrit Fluids 131:99–105
Castro-Vargas HI, Baumann W, Ferreira SRS, Parada-Alfonso F (2019) Valorization of papaya (Carica papaya L.) agroindustrial waste through the recovery of phenolic antioxidants by supercritical fluid extraction. J Food Sci Technol 56(6):3055–3066
Ferrentino G, Morozova K, Mosibo OK, Ramezani M, Scampicchio M (2018) Biorecovery of antioxidants from apple pomace by supercritical fluid extraction. J Cleaner Prod 186:253–261
Goyeneche R, Di Scala K, Ramirez CL, Fanovich MA (2020) Recovery of bioactive compounds from beetroot leaves by supercritical CO2 extraction as a promising bioresource. J Supercrit Fluids 155
Pimentel-Moral S, Borras-Linares I, Lozano-Sanchez J, Arraez-Roman D, Martinez-Ferez A, Segura-Carretero A (2019) Supercritical CO2 extraction of bioactive compounds from Hibiscus sabdariffa. J Supercrit Fluids 147:213–221
Rosello-Soto E, Barba FJ, Lorenzo JM, Munekata PES, Gomez B, Molto JC (2019) Phenolic profile of oils obtained from “horchata” by-products assisted by supercritical-CO2 and its relationship with antioxidant and lipid oxidation parameters: Triple TOF-LC-MS-MS characterization. Food Chem 274:865–871
Sahena F, Zaidul ISM, **ap S, Karim AA, Abbas KA, Norulaini NAN, Omar AKM (2009) Application of supercritical CO2 in lipid extraction-a review. J Food Eng 95(2):240–253
Sookwong P, Mahatheeranont S (2017) Supercritical CO2 extraction of rice bran oil-the technology, manufacture, and applications. J Oleo Sci 66(6):557–564
Rai A, Mohanty B, Bhargava R (2016) Supercritical extraction of sunflower oil: A central composite design for extraction variables. Food Chem 192:647–659
del Valle JM (2015) Extraction of natural compounds using supercritical CO2: Going from the laboratory to the industrial application. J Supercrit Fluids 96:180–199
Ganesan K, Sukalingam K, Xu B (2018) Impact of consumption and cooking manners of vegetable oils on cardiovascular diseases-a critical review. Trends Food Sci Technol 71:132–154
Timilsena YP, Wang B, Adhikari R, Adhikari B (2017) Advances in microencapsulation of polyunsaturated fatty acids (PUFAs)-rich plant oils using complex coacervation: A review. Food Hydrocolloids 69:369–381
Ivanovs K, Blumberga D (2017) Extraction of fish oil using green extraction methods: A short review. Energy Procedia 128:477–483
Ferdosh S, Sarker ZI, Norulaini N, Oliveira A, Yunus K, Chowdury AJ, Akanda J, Omar M (2015) Quality of tuna fish oils extracted from processing the by-products of three species of neritic tuna using supercritical carbon dioxide. J Food Process Preserv 39(4):432–441
Melgosa R, Sanz MT, Benito-Roman O, Illera AE, Beltran S (2019b) Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids. J CO2 Util 31:65–74
Soto G, Hegel P, Pereda S (2014) Supercritical production and fractionation of fatty acid esters and acylglycerols. J Supercrit Fluids 93:74–81
Zaghdoudi K, Framboisier X, Frochot C, Vanderesse R, Barth D, Kalthoum-Cherif J, Blanchard F, Guiavarc’h Y (2016) Response surface methodology applied to supercritical fluid extraction (SFE) of carotenoids from Persimmon (Diospyros kaki L.). Food Chem 208:209–219
Adadi P, Barakova NV, Krivoshapkina EF (2018) Selected methods of extracting carotenoids, characterization, and health concerns: A review. J Agric Food Chem 66(24):5925–5947
Saini RK, Keum Y-S (2018) Carotenoid extraction methods: a review of recent developments. Food Chem 240:90–103
Derrien M, Aghabararnejad M, Gosselin A, Desjardins Y, Angers P, Boumghar Y (2018) Optimization of supercritical carbon dioxide extraction of lutein and chlorophyll from spinach by-products using response surface methodology. LWT-Food Sci Technol 93:79–87
Lima MdA, Kestekoglou I, Charalampopoulos D, Chatzifragkou A (2019) Supercritical fluid extraction of carotenoids from vegetable waste matrices. Molecules 24(3):466
Tirado DF, Calvo L (2019) The Hansen theory to choose the best cosolvent for supercritical CO2 extraction of beta-carotene from Dunaliella salina. J Supercrit Fluids 145:211–218
Adejoke HT, Louis H, Amusan OO, Apebende G (2019) A review on classes, extraction, purification and pharmaceutical importance of plants alkaloid. J Med Chem Sci 2(4):130–139
Klein LC, Vander Heyden Y, Henriques AT (2016) Enlarging the bottleneck in the analysis of alkaloids: A review on sample preparation in herbal matrices. Trac-Trends Anal Chem 80:66–82
Zabot GL (2020) Decaffeination using supercritical carbon dioxide, in: Inamuddin, Asiri AM, Isloor AM (Eds.), Green sustainable process for chemical and environmental engineering and science: supercritical carbon dioxide as green solvent
De Marco I, Riemma S, Iannone R (2018) Life cycle assessment of supercritical CO2 extraction of caffeine from coffee beans. J Supercrit Fluids 133:393–400
Bermejo DV, Ibanez E, Reglero G, Fornari T (2015) Effect of cosolvents (ethyl lactate, ethyl acetate and ethanol) on the supercritical CO2 extraction of caffeine from green tea. J Supercrit Fluids 107:507–512
Ganan NA, Dias AMA, Bombaldi F, Zygadlo JA, Brignole EA, de Sousa HC, Braga MEM (2016) Alkaloids from Chelidonium majus L.: Fractionated supercritical CO2 extraction with co-solvents. Sep Purif Technol 165:199–207
Moon J, Getachew AT, Haque AT, Saravana PS, Cho Y, Nkurunziza D, Chun B (2019) Physicochemical characterization and deodorant activity of essential oil recovered from Asiasarum heterotropoides using supercritical carbon dioxide and organic solvents. J Ind Eng Chem 69:217–224
Sicari V, Poiana M (2017) Recovery of bergamot seed oil by supercritical carbon dioxide extraction and comparison with traditional solvent extraction. J Food Process Eng 40(1):e12341
Wu H, Li JL, Jia Y, **ao ZH, Li PW, **e YX, Zhang AH, Liu RK, Ren ZW, Zhao MR, Zeng CZ, Li CZ (2019) Essential oil extracted from cymbopogon citronella leaves by supercritical carbon dioxide: Antioxidant and antimicrobial activities. J Anal Methods Chem 2019:10
Sodeifian G, Sajadian SA, Ardestani NS (2016) Extraction of Dracocephalum kotschyi Boiss using supercritical carbon dioxide: Experimental and optimization. J Supercrit Fluids 107:137–144
Ndayishimiye J, Chun BS (2018) Formation, characterization and release behavior of citrus oil-polymer microparticles using particles from gas saturated solutions (PGSS) process. J Ind Eng Chem 63:201–207
Tyskiewicz K, Konkol M, Roj E (2019) Supercritical carbon dioxide (scCO(2)) extraction of phenolic compounds from Lavender (Lavandula angustifolia) flowers: a Box-Behnken experimental optimization. Molecules 24(18)
Sodeifian G, Sajadian SA, Honarvar B (2018) Mathematical modelling for extraction of oil from Dracocephalum kotschyi seeds in supercritical carbon dioxide. Nat Prod Res 32(7):795–803
Bilgic-Keles S, Sahin-Yesilcubuk N, Barla-Demirkoz A, Karakas M (2019) Response surface optimization and modelling for supercritical carbon dioxide extraction of Echium vulgare seed oil. J Supercrit Fluids 143:365–369
Tai HP, Brunner G (2019) Extraction of Oil and Minor Compounds from Oil Palm Fruit with Supercritical Carbon Dioxide. Processes 7(2)
Wejnerowska G, Ciaciuch A (2018) Optimisation of oil extraction from quinoa seeds with supercritical carbon dioxide with co-solvents. Czech J Food Sci 36(1):81–87
Mehariya S, Iovine A, Di Sanzo G, Larocca V, Martino M, Leone GP, Casella P, Karatza D, Marino T, Musmarra D, Molino A (2019) Supercritical fluid extraction of lutein from Scenedesmus almeriensis. Molecules 24(7)
Ilgaz S, Sat IG, Polat A (2018) Effects of processing parameters on the caffeine extraction yield during decaffeination of black tea using pilot-scale supercritical carbon dioxide extraction technique. J Food Sci Technol 55(4):1407–1415
Ruan X, Cui W-x, Yang L, Li Z-h, Liu B, Wang Q (2017) Extraction of total alkaloids, peimine and peiminine from the flower of Fritillaria thunbergii Miq using supercritical carbon dioxide. J CO2 Util 18:283–293
Dutta S, Bhattacharjee PJMTP (2016) Modeling of supercritical carbon dioxide extraction of piperine from Malabar black pepper. Mater Today: Proc 3(10):3238–3252
Carrara VS, Filho LC, Garcia VAS, Faioes VS, Cunha EF, Torres-Santos EC, Cortez DAG (2017) Supercritical fluid extraction of pyrrolidine alkaloid from leaves of Piper amalago L. J Evidence-Based Complementary Altern Med
Nagavekar N, Singhal RS (2018) Enhanced extraction of oleoresin from Piper nigrum by supercritical carbon dioxide using ethanol as a co-solvent and its bioactivity profile. J Food Process Eng 41(1):e12670
Dordevic V, Balanc B, Belscak-Cvitanovic A, Levic S, Trifkovic K, Kalusevic A, Kostic I, Komes D, Bugarski B, Nedovic V (2015) Trends in encapsulation technologies for delivery of food bioactive compounds. Food Eng Rev 7(4):452–490
Munin A, Edwards-Levy F (2011) Encapsulation of natural polyphenolic compounds; a review. Pharmaceutics 3(4):793–829
Silva EK, Meireles MAA (2014) Encapsulation of food compounds using supercritical technologies: Applications of supercritical carbon dioxide as an antisolvent. Food and Public Health 4(5):247–258
Temelli F (2018) Perspectives on the use of supercritical particle formation technologies for food ingredients. J Supercrit Fluids 134:244–251
Sihvonen M, Jarvenpaa E, Hietaniemi V, Huopalahti R (1999) Advances in supercritical carbon dioxide technologies. Trends Food Sci Technol 10(6–7):217–222
Martello RH, Gallon C, Souza MA, Calisto JFF, Aguiar GPS, Albeny-Simoes D, Oliveira JV, Dal Magro J (2019) Micronization of thymol by RESS and its larvicidal activity against Aedes aegypti (Diptera, Culicidae). Ind Crops Prod 139
Soh SH, Lee LY (2019) Microencapsulation and Nanoencapsulation Using Supercritical Fluid (SCF) Techniques. Pharmaceutics 11(1)
Wang BC, Su CS (2020) Solid solubility measurement of ipriflavone in supercritical carbon dioxide and microparticle production through the rapid expansion of supercritical solutions process. J CO2 Util 37:285–294
Jung J, Perrut M (2001) Particle design using supercritical fluids: Literature and patent survey. J Supercrit Fluids 20(3):179–219
Gomes MT, Santana ÁL, Santos DT, Meireles MA (2019) Trends on the rapid expansion of supercritical solutions process applied to food and non-food industries. Recent Pat Food, Nutr Agric 10(2):82–92
Weidner E (2009) High pressure micronization for food applications. J Supercrit Fluids 47(3):556–565
Momenkiaei F, Raofie F (2018) Preparation of silybum marianum seeds extract nanoparticles by supercritical solution expansion. J Supercrit Fluids 138:46–55
Momenkiaei F, Raofie F (2019) Preparation of Curcuma Longa L. Extract Nanoparticles Using Supercritical Solution Expansion. J Pharm Sci 108(4):1581–1589
Tsai WC, Rizvi SSH (2016) Liposomal microencapsulation using the conventional methods and novel supercritical fluid processes. Trends Food Sci Technol 55:61–71
Tsai WC, Rizvi SSH (2017a) Microencapsulation and characterization of liposomal vesicles using a supercritical fluid process coupled with vacuum-driven cargo loading. Food Res Int 96:94–102
Tsai WC, Rizvi SSH (2017b) Simultaneous microencapsulation of hydrophilic and lipophilic bioactives in liposomes produced by an ecofriendly supercritical fluid process. Food Res Int 99:256–262
Rojas A, Torres A, Galotto MJ, Guarda A, Julio R (2020) Supercritical impregnation for food applications: A review of the effect of the operational variables on the active compound loading. Crit Rev Food Sci Nutr 60(8):1290–1301
Milovanovic S, Hollermann G, Errenst C, Pajnik J, Frerich S, Kroll S, Rezwan K, Ivanovic J (2018) Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging. Food Res Int 107:486–495
Sanchez-Sanchez J, Fernandez-Ponce MT, Casas L, Mantell C, de la Ossa EJM (2017) Impregnation of mango leaf extract into a polyester textile using supercritical carbon dioxide. J Supercrit Fluids 128:208–217
Bastante CC, Cardoso LC, Fernandez-Ponce MT, Serrano CM, de la Ossa EJM (2019) Supercritical impregnation of olive leaf extract to obtain bioactive films effective in cherry tomato preservation. Food packaging shelf 21
Pantić M, Knez Ž, Novak Z (2016) Supercritical impregnation as a feasible technique for entrapment of fat-soluble vitamins into alginate aerogels. J Non-Cryst Solids 432:519–526
Alvarado N, Romero J, Torres A, de Dicastillo CL, Rojas A, Galotto MJ, Guarda A (2018) Supercritical impregnation of thymol in poly(lactic acid) filled with electrospun poly(vinyl alcohol)-cellulose nanocrystals nanofibers: Development an active food packaging material. J Food Eng 217:1–10
Fahim TK, Zaidul ISM, Abu Bakar MR, Salim UM, Awang MB, Sahena F, Jalal KCA, Sharif KM, Sohrab MH (2014) Particle formation and micronization using non-conventional techniques-review. Chem Eng Process 86:47–52
Knez Z, Hrncic MK, Skerget M (2015) Particle formation and product formulation using supercritical fluids, in: Prausnitz JM (Ed.), Annual Review of Chemical and Biomolecular Engineering, Vol 6. Annual Reviews, Palo Alto
Gil-Ramirez A, Rodriguez-Meizoso I (2019) Purification of natural products by selective precipitation using supercritical/gas antisolvent techniques (SAS/GAS). Sep Purif Rev:1–21
Janiszewska-Turak E (2017) Carotenoids microencapsulation by spray drying method and supercritical micronization. Food Res Int 99:891–901
Montes A, Hanke F, Williamson D, Guaman-Balcazar MC, Valor D, Pereyra C, Teipel U, de la Ossa EM (2019) Precipitation of powerful antioxidant nanoparticles from orange leaves by means of supercritical CO2. J CO2 Util 31:235–243
Jung J, Clavier J-Y, Perrut M (2003) Gram to kilogram scale-up of supercritical anti-solvent process, Proceedings of the 6th International Symposium on Supercritical Fluids, pp. 1683–1688
Prieto C, Calvo L (2017) The encapsulation of low viscosity omega-3 rich fish oil in polycaprolactone by supercritical fluid extraction of emulsions. J Supercrit Fluids 128:227–234
Reis P, Mezzomo N, Aguiar GPS, Senna E, Hense H, Ferreira SRS (2019) Ultrasound-assisted emulsion of laurel leaves essential oil (Laurus nobilis L.) encapsulated by SFEE. J Supercrit Fluids 147:284–292
Levai G, Albarelli JQ, Santos DT, Meireles MAA, Martin A, Rodriguez-Rojo S, Cocero MJ (2017) Quercetin loaded particles production by means of supercritical fluid extraction of emulsions: Process scale-upstudy and thermo-economic evaluation. Food Bioprod Process 103:27–38
Soukoulis C, Bohn T (2018) A comprehensive overview on the micro- and nano-technological encapsulation advances for enhancing the chemical stability and bioavailability of carotenoids. Crit Rev Food Sci Nutr 58(1):1–36
Ndayishimiye J, Ferrentino G, Nabil H, Scampicchio M (2020) Encapsulation of oils recovered from brewer’s spent grain by particles from gas saturated solutions technique. Food Bioprocess Technol 13(2):256–264
Getachew AT, Chun BS (2016) Optimization of coffee oil flavor encapsulation using response surface methodology. LWT-Food Sci Technol 70:126–134
Haq M, Chun BS (2018) Microencapsulation of omega-3 polyunsaturated fatty acids and astaxanthin-rich salmon oil using particles from gas saturated solutions (PGSS) process. LWT-Food Sci Technol 92:523–530
Goncalves VSS, Poejo J, Matias AA, Rodriguez-Rojo S, Cocero MJ, Duarte CMM (2016) Using different natural origin carriers for development of epigallocatechin gallate (EGCG) solid formulations with improved antioxidant activity by PGSS-drying. RSC Adv 6(72):67599–67609
Melgosa R, Benito-Roman O, Sanz MT, de Paz E, Beltran S (2019) Omega-3 encapsulation by PGSS-drying and conventional drying methods. Particle characterization and oxidative stability. Food Chem 270:138–148
Levai G, Martin A, Moro A, Matias AA, Goncalves VSS, Bronze MR, Duarte CMM, Rodriguez-Rojo S, Cocero MJ (2017) Production of encapsulated quercetin particles using supercritical fluid technologies. Powder Technol 317:142–153
Chauvet M, Sauceau M, Fages J (2017) Extrusion assisted by supercritical CO2: A review on its application to biopolymers. J Supercrit Fluids 120:408–420
Sauceau M, Fages J, Common A, Nikitine C, Rodier E (2011) New challenges in polymer foaming: A review of extrusion processes assisted by supercritical carbon dioxide. Prog Polym Sci 36(6):749–766
Rizvi SS, Mulvaney S (1992) Extrusion processing with supercritical fluids. Google Patents
Rizvi S, Mulvaney S, Sokhey A (1995) The combined application of supercritical fluid and extrusion technology. Trends Food Sci Technol 6(7):232–240
Lv Y, Glahn RP, Hebb RL, Rizvi SSH (2018) Physico-chemical properties, phytochemicals and DPPH radical scavenging activity of supercritical fluid extruded lentils. LWT-Food Sci Technol 89:315–321
Alavi S, Gogoi B, Khan M, Bowman B, Rizvi S (1999) Structural properties of protein-stabilized starch-based supercritical fluid extrudates. Food Res Int 32(2):107–118
Afizah MN, Rizvi SSH (2014) Functional properties of whey protein concentrate texturized at acidic pH: Effect of extrusion temperature. LWT-Food Sci Technol 57(1):290–298
Manoi K, Rizvi SSH (2008) Rheological characterizations of texturized whey protein concentrate-based powders produced by reactive supercritical. Food Res Int 41(8):786–796
Bashir S, Sharif MK, Butt MS, Rizvi SS, Paraman I, Ejaz R (2017) Preparation of micronutrients fortified Spirulina supplemented Rice-soy crisps processed through novel supercritical fluid extrusion. J Food Process Preserv 41(3):e12986
Sharif MK, Rizvi SSH, Paraman I (2014) Characterization of supercritical fluid extrusion processed rice-soy crisps fortified with micronutrients and soy protein. LWT-Food Sci Technol 56(2):414–420
Sun VZ, Paraman I, Rizvi SSH (2015) Supercritical fluid extrusion of protein puff made with fruit pomace and liquid whey. Food Bioprocess Technol 8(8):1707–1715
Liu H, Hebb RL, Putri N, Rizvi SS (2018) Physical properties of supercritical fluid extrusion products composed of milk protein concentrate with carbohydrates. Int J Food Sci Technol 53(3):847–856
Yoon AK, Rizvi SS (2020) Functional, textural, and sensory properties of milk protein concentrate-based supercritical fluid extrudates made with acid whey. Int J Food Prop 23(1):708–721
Ivanovic J, Milovanovic S, Zizovic I (2016) Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials. Starch-Starke 68(9–10):821–833
Montes A, Merino R, De los Santos DM, Pereyra C, de la Ossa EJM (2017) Micronization of vanillin by rapid expansion of supercritical solutions process. J CO2 Util 21:169–176
Jiao Z, Wang XD, Han S, Zha XJ, **a JX (2019) Preparation of vitamin C liposomes by rapid expansion of supercritical solution process: Experiments and optimization. J Drug Delivery Sci Technol 51:1–6
Karimi M, Raofie F (2019) Micronization of vincristine extracted from Catharanthus roseus by expansion of supercritical fluid solution. J Supercrit Fluids 146:172–179
Bastante CC, Cardoso LC, Serrano CM, de la Ossa EM (2017) Supercritical impregnation of food packaging films to provide antioxidant properties. J Supercrit Fluids 128:200–207
Rojas A, Torres A, Añazco A, Villegas C, Galotto MJ, Guarda A, Romero J (2018) Effect of pressure and time on scCO2-assisted incorporation of thymol into LDPE-based nanocomposites for active food packaging. J CO2 Util 26:434–444
Quintana SE, Hernandez DM, Villanueva-Bermejo D, Garcia-Risco MR, Fornari T (2020) Fractionation and precipitation of licorice (Glycyrrhiza glabra L.) phytochemicals by supercritical antisolvent (SAS) technique. LWT-Food Sci Technol 126
Machado APD, Rezende CA, Rodrigues RA, Barbero GF, Rosa P, Martinez J (2018) Encapsulation of anthocyanin-rich extract from blackberry residues by spray-drying, freeze-drying and supercritical antisolvent. Powder Technol 340:553–562
Guaman-Balcazar MC, Montes A, Pereyra C, de la Ossa EM (2019) Production of submicron particles of the antioxidants of mango leaves/PVP by supercritical antisolvent extraction process. J Supercrit Fluids 143:294–304
Rosa M, Alvarez VH, Albarelli JQ, Santos DT, Meireles MAA, Saldana MDA (2019) Supercritical anti-solvent process as an alternative technology for vitamin complex encapsulation using zein as wall material: Technical-economic evaluation. J Supercrit Fluids 159
Kaga K, Honda M, Adachi T, Honjo M, Wahyudiono KH, Goto M (2018) Nanoparticle formation of PVP/astaxanthin inclusion complex by solution enhanced dispersion by supercritical fluids (SEDS): Effect of PVP and astaxanthin Z-isomer content. J Supercrit Fluids 136:44–51
Lee WJ, Tan CP, Sulaiman R, Hee YY, Chong GH (2020) Storage stability and degradation kinetics of bioactive compounds in red palm oil microcapsules produced with solution-enhanced dispersion by supercritical carbon dioxide: A comparison with the spray-drying method. Food Chem 304
Mendonca FMR, Polloni AE, Junges A, da Silva RS, Rubirad AF, Borges GR, Dariva C, Franceschi E (2019) Encapsulation of neem (Azadirachta indica) seed oil in poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by SFEE technique. J Supercrit Fluids 152
Cruz PN, Reis P, Ferreira SRS, Masson ML, Corazza ML (2020) Encapsulation of yacon (Smallanthus sonchifolius) leaf extract by supercritical fluid extraction of emulsions. J Supercrit Fluids 160
Ndayishimiye J, Lim DJ, Chun BS (2018) Antioxidant and antimicrobial activity of oils obtained from a mixture of citrus by-products using a modified supercritical carbon dioxide. J Ind Eng Chem 57:339–348
Ferrentino G, Spilimbergo S (2011) High pressure carbon dioxide pasteurization of solid foods: Current knowledge and future outlooks. Trends Food Sci Technol 22(8):427–441
Perrut M (2012) Sterilization and virus inactivation by supercritical fluids (a review). J Supercrit Fluids 66:359–371
Soares GC, Learmonth DA, Vallejo MC, Davila SP, González P, Sousa RA, Oliveira AL (2019) Supercritical CO2 technology: The next standard sterilization technique? Mater Sci Eng: C 99:520–540
Fraser D (1951) Bursting bacteria by release of gas pressure. Nature 167(4236):33–34
Xu FY, Feng FM, Sui X, Lin H, Han YG (2017) Inactivation mechanism of Vibrio parahaemolyticus via supercritical carbon dioxide treatment. Food Res Int 100:282–288
Chen YY, Temelli F, Ganzle MG (2017) Mechanisms of Inactivation of Dry Escherichia coli by High-Pressure Carbon Dioxide. Appl Environ Microbiol 83(10)
Silva EK, Alvarenga VO, Bargas MA, Sant’Ana AS, Meireles MAA (2018) Non-thermal microbial inactivation by using supercritical carbon dioxide: Synergic effect of process parameters. J Supercrit Fluids 139:97–104
Fleury C, Savoire R, Harscoat-Schiavo C, Hadj-Sassi A, Subra-Patemault P (2018) Optimization of supercritical CO2 process to pasteurize dietary supplement: Influencing factors and CO2 transfer approach. J Supercrit Fluids 141:240–251
Li H, Xu ZZ, Zhao F, Wang YT, Liao XJ (2016) Synergetic effects of high-pressure carbon dioxide and nisin on the inactivation of Escherichia coli and Staphylococcus aureus. Innovative Food Sci Emerging Technol 33:180–186
González-Alonso V, Cappelletti M, Bertolini FM, Lomolino G, Zambon A, Spilimbergo S (2019) Microbial inactivation of raw chicken meat by supercritical carbon dioxide treatment alone and in combination with fresh culinary herbs. Poult Sci 99(1):536–545
Sikin AM, Walkling-Ribeiro M, Rizvi SSH (2016) Synergistic effect of supercritical carbon dioxide and peracetic acid on microbial inactivation in shredded Mozzarella-type cheese and its storage stability at ambient temperature. Food Control 70:174–182
Gomez-Gomez A, Brito-de la Fuente E, Gallegos C, Garcia-Perez JV, Benedito J (2020) Non-thermal pasteurization of lipid emulsions by combined supercritical carbon dioxide and high-power ultrasound treatment. Ultrason Sonochem 67:105138
Paniagua-Martinez I, Mulet A, Garcia-Alvarado MA, Benedito J (2018) Orange juice processing using a continuous flow ultrasound-assisted supercritical CO2 system: Microbiota inactivation and product quality. Innovative Food Sci Emerging Technol 47:362–370
Setlow P (2016) Spore resistance properties, in: Driks. A, Eichenberger. P (Eds.), The Bacterial Spore. Wiley, Washington, DC
Rao L, Wang YT, Chen F, Liao XJ (2016a) The synergistic effect of high pressure CO2 and nisin on inactivation of Bacillus subtilis spores in aqueous solutions. Front Microbiol 7
Setlow B, Korza G, Blatt KMS, Fey JP, Setlow P (2015) Mechanism of Bacillus subtilis spore inactivation by and resistance to supercritical CO2 plus peracetic acid. J Appl Microbiol 120(1):57–69
Rao L, Bi XF, Zhao F, Wu JH, Hu XS, Liao XJ (2015) Effect of high-pressure CO2 Processing on bacterial spores. Crit Rev Food Sci Nutr 56(11):1808–1825
Spilimbergo S, Bertucco A (2003) Non-thermal bacterial inactivation with dense CO2. Biotechnol Bioeng 84(6):627–638
Rao L, Zhao F, Wang YT, Chen F, Hu XS, Liao XJ (2016b) Investigating the Inactivation Mechanism of Bacillus subtilis Spores by High Pressure CO2. Front Microbiol 7
Rao L, Zhao L, Wang YT, Chen F, Hu XS, Setlow P, Liao XJ (2019) Mechanism of inactivation of Bacillus subtilis spores by high pressure CO2 at high temperature. Food Microbiol 82:36–45
Rao L, Wang YT, Chen F, Hu XS, Liao XJ, Zhao L (2020) High pressure CO2 reduces the wet heat resistance of Bacillus subtilis spores by perturbing the inner membrane. Innovative Food Sci Emerging Technol 60:102291
Benito-Roman O, Sanz MT, Illera AE, Melgosa R, Benito JM, Beltran S (2019) Pectin methylesterase inactivation by high pressure carbon dioxide (HPCD). J Supercrit Fluids 145:111–121
Briongos H, Illera AE, Sanz MT, Melgosa R, Beltran S, Solaesa AG (2016) Effect of high pressure carbon dioxide processing on pectin methylesterase activity and other orange juice properties. LWT-Food Sci Technol 74:411–419
Murtaza A, Iqbal A, Zhu LH, Yan L, Xu XY, Pan SY, Hu WF (2019) Effect of high-pressure carbon dioxide on the aggregation and conformational changes of polyphenol oxidase from apple (Malus domestica) juice. Innovative Food Sci Emerging Technol 54:43–50
Liao H, Zhong K, Hu X, Liao X (2019) Effect of high pressure carbon dioxide on alkaline phosphatase activity and quality characteristics of raw bovine milk. Innovative Food Sci Emerging Technol 52:457–462
Damar S, Balaban MO (2006) Review of dense phase CO2 technology: Microbial and enzyme inactivation, and effects on food quality. J Food Sci 71(1):R1–R11
Iqbal A, Murtaza A, Hu W, Ahmad I, Ahmad A, Xu X (2019) Activation and inactivation mechanisms of polyphenol oxidase during thermal and non-thermal methods of food processing. Food Bioprod Process 117:170–182
Marszalek K, Doesburg P, Starzonek S, Szczepanska J, Wozniak L, Lorenzo JM, Skapska S, Rzoska S, Barba FJ (2019) Comparative effect of supercritical carbon dioxide and high pressure processing on structural changes and activity loss of oxidoreductive enzymes. J CO2 Util 29:46–56.
Illera A, Sanz M, Trigueros E, Beltrán S, Melgosa R (2018) Effect of high pressure carbon dioxide on tomato juice: Inactivation kinetics of pectin methylesterase and polygalacturonase and determination of other quality parameters. J Food Eng 239:64–71
Zambon A, Michelino F, Bourdoux S, Devlieghere F, Sut S, Dall’Acqua S, Rajkovic A, Spilimbergo S (2018) Microbial inactivation efficiency of supercritical CO2 drying process. Drying Technol 36(16):2016–2021
Morbiato G, Zambon A, Toffoletto M, Poloniato G, Dall’Acqua S, de Bernard M, Spilimbergo S (2019) Supercritical carbon dioxide combined with high power ultrasound as innovate drying process for chicken breast. J Supercrit Fluids 147:24–32
Zambon A, Tomic N, Djekic I, Hofland G, Rajkovic A, Spilimbergo S (2020) Supercritical CO2 drying of red bell pepper. Food Bioprocess Technol:11
Zambon A, Bourdoux S, Pantano MF, Pugno NM, Boldrin F, Hofland G, Rajovic AK, Devlieghere F, Spilimbergo S (2019) Supercritical CO2 for the drying and microbial inactivation of apple's slices. Drying Technol:1–9
Busic A, Vojvodic A, Komes D, Akkermans C, Belscak-Cvitanovic A, Stolk M, Hofland G (2014) Comparative evaluation of CO2 drying as an alternative drying technique of basil (Ocimum basilicum L.)-the effect on bioactive and sensory properties. Food Res Int 64:34–42
Braeuer AS, Schuster JJ, Gebrekidan MT, Bahr L, Michelino F, Zambon A, Spilimbergo S (2017) In situ Raman analysis of CO2-assisted drying of fruit-slices. Foods 6(5):37
Khalloufi S, Almeida-Rivera C, Bongers P (2010) Supercritical-CO2 drying of foodstuffs in packed beds: experimental validation of a mathematical model and sensitive analysis. J Food Eng 96(1):141–150
Brown ZK, Fryer PJ, Norton IT, Bakalis S, Bridson RH (2008) Drying of foods using supercritical carbon dioxide-investigations with carrot. Innovative Food Sci Emerging Technol 9(3):280–289
Djekic I, Tomic N, Bourdoux S, Spilimbergo S, Smigic N, Udovicki B, Hofland G, Devlieghere F, Rajkovic A (2018) Comparison of three types of drying (supercritical CO2, air and freeze) on the quality of dried apple-quality index approach. LWT-Food Sci Technol 94:64–72
Michelino F, Zambon A, Vizzotto MT, Cozzi S, Spilimbergo S (2018) High power ultrasound combined with supercritical carbon dioxide for the drying and microbial inactivation of coriander. J CO2 Util 24:516–521
Cuppini M, Zeni J, Barbosa J, Franceschi E, Toniazzo G, Cansian RL (2016) Inactivation of Staphylococcus aureus in raw salmon with supercritical CO2 using experimental design. Food Sci Technol 36:8–11
Porebska I, Sokolowska B, Skapska S, Rzoska SJ (2017) Treatment with high hydrostatic pressure and supercritical carbon dioxide to control Alicyclobacillus acidoterrestris spores in apple juice. Food Control 73:24–30
Marszalek K, Krzyzanowska J, Wozniak L, Skapska S (2016) Kinetic modelling of tissue enzymes inactivation and degradation of pigments and polyphenols in cloudy carrot and celery juices under supercritical carbon dioxide. J Supercrit Fluids 117:26–32
Ceni G, Silva MF, Valerio C, Cansian RL, Oliveira JV, Rosa CD, Mazutti MA (2016) Continuous inactivation of alkaline phosphatase and Escherichia coli in milk using compressed carbon dioxide as inactivating agent. J CO2 Util 13:24–28
Acknowledgements
The authors would like to thank the organizer of the International Nonthermal Processing Workshops and Short Courses 2019 in Monterrey, Mexico, especially J. Antonio Torres for his kind invitation. This work was partly supported by the National Key Research & Development Program of China (Grant 2018YFD0400500 and 2018YFD0400503) and “Agricultural Scientific Research Outstanding Talent Training Project” of China.
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Wang, W., Rao, L., Wu, X. et al. Supercritical Carbon Dioxide Applications in Food Processing. Food Eng Rev 13, 570–591 (2021). https://doi.org/10.1007/s12393-020-09270-9
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DOI: https://doi.org/10.1007/s12393-020-09270-9