Abstract
Quince (Cydonia oblonga Mill.) is the one and only specie of the genus Cydonia in the Rosacea family. Quince contains bioactive constituents such as alkaloids, saccharides, flavonoids, and volatile oils. Nevertheless, seldom researches have concentrated on quince essential oil (QEO). The chemical composition, cellular activity, antioxidant activity, and α-glucose inhibition activity of the plant were studied. QEO was isolated using hydrodistillation technique, and the yield was 1.3 mL/kg. A total of 52 chemical constituents in QEO were determined by gas chromatography-mass spectrometry (GC–MS). The main components (> 3.0%) found in the QEO were methyl (Z)-octadec-6-enoate (16.2%), methyl linoleate (10.0%), cedrenol (8.8%), methyl hexadecanoate (7.2%), methyl palmitoleate (7.2%), dibutyl phthalate (5.4%), hexadecanal (4.7%), 12,15-octadecatrienoicacid, ethylester, (Z,Z,Z)-9 (4.2%), α-eudesmol (3.5%), terpinen-4-ol (3.3%), and palmitic acid (3.2%). The antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method. Then, the α-glucose inhibitory activity of the essential oil was analyzed. We investigated the effects of this plant on NO production and cell viability in H2O2–induced oxidative stress HUVCEs. The results showed that the QEO had significant antioxidant activity and α-glucose inhibitory effect. Furthermore, the results revealed that QEO could protect HUVECs from oxidative stress and effectively inhibited NO production in that condition. To summarize, the results of this study demonstrated the excellent cellular and antioxidant activity of QEO, and it has potential biological significance in the treatment of cardiovascular diseases.
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Funding
This work was supported by the youth innovation team of colleges and universities in Shandong Province (2019KJM005), Shandong traditional Chinese medicine science, and technology development plan project (2019–0021).
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All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by Lu** Sun and Zhenhua Tian. Yifei Bian helped test the cell viability of essential oil, and Bingqing Chi helped test the biological activity of essential oil. The first draft of the manuscript was written by Lu** Sun, and Zhenhua Tian critically revised the work. Finally, all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Lu** Sun declares that he has no conflict of interest. Hongyan Liu declares that she has no conflict of interest. Bingqing Chi declares that she has no conflict of interest. Yifei Bian declares that he has no conflict of interest. Honglei Zhou declares that he has no conflict of interest. Zhenhua Tian declares that he has no conflict of interest.
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Sun, L., Liu, H., Chi, B. et al. Analysis and Bioactivity of Volatile Oil from Cydonia oblonga Fruit by GC–MS. Food Anal. Methods 15, 2725–2733 (2022). https://doi.org/10.1007/s12161-022-02278-3
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DOI: https://doi.org/10.1007/s12161-022-02278-3