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Histopathology Findings in Patients Undergoing Laparoscopic Sleeve Gastrectomy

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Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) has gained popularity in the last 10 years for its good results in weight loss and comorbidity control. However, guidelines on the pathological examination of the specimen are lacking. The aim of this retrospective study was to determine the usefulness of the routine specimen examination when presurgery endoscopy (upper gastrointestinal endoscopy, UGIE) and multiple gastric biopsies are part of the preoperative work-up.

Methods

A retrospective review of records of the patients submitted to LSG between January 2012 and August 2017 was carried out. Sex, age, histopathology findings in the presurgery endoscopy biopsies and surgical specimen, and the prevalence of Helicobacter pylori infection were analyzed.

Results

A total of 925 patients entered the study group (mean age = 44.1 years, Females = 80.3%, BMI = 44.58 kg/m2). The most common histopathology pattern in the endoscopy biopsies and in the surgical specimens was inactive chronic gastritis (64.4 and 55.6%, respectively). Helicobacter pylori infection was 24.6 and 2.48%, respectively. Ninety-nine percent (n 796) of patients with non-significant endoscopy biopsy findings showed the same patterns in specimen analysis. Only three patients (0.3%) who had intestinal presurgery metaplasia were positive in the specimen analysis, and two cases of gastric stromal neoplasms (gastrointestinal stromal tumor and gastric leiomyoma) were found intraoperatively.

Conclusion

Most of the findings are non-significant and can be predicted if UGIE plus multiple biopsies is routinely included in the bariatric work-up with significant cost reduction. In those patients who had a significant finding prior to the surgery or intraoperatively, the pathological examination of the specimen is recommended.

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Author notes

  1. Ammiel Martínez Canil and Angelo Iossa contributed equally to this work.

Authors and Affiliations

  1. Department of Medico-Surgical Sciences and Biotechnologies, Division of General Surgery, Bariatric & Metabolic Center of Excellence (IFSO European Chapter), Center of Excellence (SICOB – Italian Society of Bariatric and Metabolic Surgery), La Sapienza University of Rome, Via F. Faggiana 1668, 04100, Latina, Italy

    Ammiel Martínez Canil, Angelo Iossa, Pietro Termine, Daniela Caporilli & Gianfranco Silecchia

  2. Medical Sciences Faculty, Postgraduate Secretary, Pablo Mirizzi Scholarship Program, National University of Cordoba, Avenue Haya de la Torre, Ciudad Universitaria, 5000, Córdoba, Argentina

    Ammiel Martínez Canil

  3. Pathology Unit, ICOT Ospedale, La Sapienza University of Rome, Via F. Faggiana 1668, 04100, Latina, Italy

    Vincenzo Petrozza

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  1. Ammiel Martínez Canil
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Corresponding author

Correspondence to Ammiel Martínez Canil.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

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Canil, A.M., Iossa, A., Termine, P. et al. Histopathology Findings in Patients Undergoing Laparoscopic Sleeve Gastrectomy. OBES SURG 28, 1760–1765 (2018). https://doi.org/10.1007/s11695-017-3092-9

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