Abstract
Background
The adverse effect of low-dose CT on image quality may be mitigated using iterative reconstructions. The purpose of this study was to evaluate the performance of the full model-based iterative reconstruction (MBIR) and adaptive statistical reconstruction (ASIR) algorithms in low radiation dose and low contrast dose abdominal contrast-enhanced CT (CECT) in children.
Methods
A total of 59 children (32 males and 27 females) undergoing low radiation dose (100kVp) and low contrast dose (270 mgI/ml) abdominal CECT were enrolled. The median age was 4.0 years (ranging from 0.3 to 13 years). The raw data were reconstructed with MBIR, ASIR and filtered back-projection (FBP) algorithms into 6 groups (MBIR, 100%ASIR, 80%ASIR, 60%ASIR, 40%ASIR and FBP). The CT numbers, standard deviations, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of liver, pancreas, kidney and abdominal aorta were measured. Two radiologists independently evaluated the subjective image quality including the overall image noise and structure display ability on a 4-point scale with 3 being clinically acceptable. The measurements among the reconstruction groups were compared using one-way ANOVA.
Results
The overall image noise score and display ability were 4.00 ± 0.00 and 4.00 ± 0.00 with MBIR and 3.27 ± 0.33 and 3.25 ± 0.43 with ASIR100%, respectively, which met the diagnostic requirement; other reconstructions couldn’t meet the diagnostic requirements. Compared with FBP images, the noise of MBIR images was reduced by 62.86–65.73% for the respective organs (F = 48.15–80.47, P < 0.05), and CNR increased by 151.38–170.69% (F = 22.94–38.02, P < 0.05).
Conclusions
MBIR or ASIR100% improves the image quality of low radiation dose and contrast dose abdominal CT in children to meet the diagnostic requirements, and MBIR has the best performance.
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Acknowledgements
The authors would like to express our sincere thanks to Dr. Jianying Li for his technical support in understanding the model-based iterative reconstruction algorithm.
Funding
This study was supported by the Bei**g Children’s Hospital Young Investigator Program (Grant Numbers BCH-YIPB-2016–06) and Clinical Technology Innovation Project of Bei**g Municipal Commission (Grant Numbers xmlx201407).
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The present study was approved by the Ethics Committee of Bei**g Children’s Hospital. The legal guardian of all the children signed written informed consents.
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Sun, J., Yang, L., Zhou, Z. et al. Performance evaluation of two iterative reconstruction algorithms, MBIR and ASIR, in low radiation dose and low contrast dose abdominal CT in children. Radiol med 125, 918–925 (2020). https://doi.org/10.1007/s11547-020-01191-1
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DOI: https://doi.org/10.1007/s11547-020-01191-1