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Two new antibacterial norabietane diterpenoids from cyanobacteria, Microcoleous lacustris

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Abstract

Two abietane diterpenes were isolated from cyanobacteria Microcoleous lacustris, 20-nor-3α-acetoxyabieta-5,7,9,11,13-pentaene and 20-nor-3α-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene. These compounds were assayed against Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Vibrio cholerae, Bacillus subtilis, Bacillus cereus, Escherichia coli, and Klebsiella pneumoniae. Both compounds showed activity against S. aureus, S. epidermidis, S. typhi, and V. cholerae, but not against the other bacteria.

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References

  1. Skulger CM (2000) Microalgae as a source of bioactive molecules—experience from cyanophyte research. J Appl Phycol 12:341–348

    Article  Google Scholar 

  2. Valadez CF, Carmona J, Cantoral UE (1996) Algas de ambientes lóticos del estado de Morelos, México. An Inst Biol Univ Nac Autón México Ser Bot 67:227–282

    Google Scholar 

  3. Perez GRM, Vargas SR (2007) Cardioactive effects from freshwater algae Oscillatoria limnetica, Hydrodictyon reticulatum, and Microcoleous lacustris. Pharmacogn Med 3:159–162

    Google Scholar 

  4. NCCLS (1997) Performance standards for antibacterial disk susceptibility tests, 6th edn. Approved standard, NCCLS document M2-A6, vol. 17, no 1. Wayne, PA

  5. NCCLS (1997) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th edn. Approved standard. NCCLS document M7-A4, vo1. 17, no 2. Wayne, PA

  6. NCCLS (1998) Performance standards for antimicrobial susceptibility testing; 8th informational supplement. NCCLS document M100-S8, vo1. 18, no 1. Wayne, PA

  7. Mensah AY, Houghton PJ, Bloomfield S, Vlietinvk A, Berghe DV (2000) Known and novel terpenes from Buddleja globosa displaying selective antifungal activity against dermatophytes. J Nat Prod 63:1210–1213

    Article  PubMed  CAS  Google Scholar 

  8. Kinouchi Y, Ohtsu H, Tokuda H, Nishino H, Matsunaga S, Tanaka R (2000) Potential antitumor-promoting diterpenoids from the stem bark of Picea glehni. J Nat Prod 63:817–820

    Article  PubMed  CAS  Google Scholar 

  9. Moujir L, Gutierrez-Navarro AM, San Andres L, Luis JG (1996) Bioactive diterpenoids isolated from Salvia mellifera. Phytoter Res 10:172–174

    Article  CAS  Google Scholar 

  10. Ulubelen A, Topcu G, Johanson CB (1997) Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity. J Nat Prod 60:1275–1280

    Article  PubMed  CAS  Google Scholar 

  11. Ulubelen A, Evren N, Tuzlaci E, Johansson C (1988) Diterpenoids from the roots of Salvia hypargeia. J Nat Prod 51:1178–1183

    Article  PubMed  CAS  Google Scholar 

  12. Woldemichael GM, Watchter G, Singh MP, Maiese W, Timmermann BN (2003) Antibacterial diterpenes from Calceolaria pinifolia. J Nat Prod 66:242–246

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Natural Products Research Laboratory, Industrias Extractivas (ESIQUIE)-IPN, Punto Fijo 16, Col. Torres Lindavista, C.P. 07708, Mexico D.F., Mexico

    Rosa Martha Pérez Gutiérrez

  2. Phytopharmacology Research Laboratory, Universidad Autónoma Metropolitana-Xochimilco, A.P. 23-181, Mexico D.F., Mexico

    Amalia Martínez Flores & Rosario Vargas Solís

  3. Ficology Laboratory, Facultad de Ciencias UNAM, C.P. 04510, Mexico D.F., Mexico

    Javier Carmona Jimenez

Authors
  1. Rosa Martha Pérez Gutiérrez
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  2. Amalia Martínez Flores
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  3. Rosario Vargas Solís
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  4. Javier Carmona Jimenez
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Correspondence to Rosa Martha Pérez Gutiérrez.

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Pérez Gutiérrez, R.M., Martínez Flores, A., Vargas Solís, R. et al. Two new antibacterial norabietane diterpenoids from cyanobacteria, Microcoleous lacustris . J Nat Med 62, 328–331 (2008). https://doi.org/10.1007/s11418-008-0238-z

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  • DOI: https://doi.org/10.1007/s11418-008-0238-z

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