References
Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, Wang YC, Loh YE, Jiang JX, Surmeier DJ, Robson SC, Junger WG, Sebra R, Calipari ES, Kenny PJ, Eyo UB, Colonna M, Quintana FJ, Wake H, Gradinaru V, Schaefer A (2020) Negative feedback control of neuronal activity by microglia. Nature. 586(7829):417–423. https://doi.org/10.1038/s41586-020-2777-8
Izquierdo P, Attwell D, Madry C (2019) Ion channels and receptors as determinants of microglial function. Trends Neurosci 42(4):278–292. https://doi.org/10.1016/j.tins.2018.12.007
Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, Julius D (2006) The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nature Neurosci 9(12):1512–1519. https://doi.org/10.1038/nn1805
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical approval
This article does not contain any studies with human participants or animals performed by any of the authors.
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Dong, YT., Tang, Y. Purinergic signalling mediates the inhibitory effect of microglia on neuronal activity in the brain. Purinergic Signalling 16, 477–478 (2020). https://doi.org/10.1007/s11302-020-09759-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11302-020-09759-2