SpringerLink
Log in

Interaction of different lasers beams with synthesized H2Ti3O7 nanotubes: toward photodynamic therapy

  • Published:
Optical and Quantum Electronics Aims and scope Submit manuscript

Abstract

The interaction of laser beams with metal oxide nanoparticles can be proposed for water remediation and cancer treatment. In this paper, H2Ti3O7 nanotubes (NTs) were synthesized by anodization technique and characterized using UV–visible, Raman scattering and FTIR and spectroscopies, field emission scanning and transmission electron microscopy, zeta potential, thermal analysis, and X-ray diffraction. The results declare that monoclinic hydrogen titanium oxide with a mean crystallite size of 16.0 nm is formed. The H2Ti3O7 NTs also have an average outer diameter and shell thickness of 34.0 nm and 1.69 nm, respectively. Furthermore, the NTs have considerable thermal stability and high colloidal stability with a negative surface charge value of − 39.6 mV. Additionally, the interactions of different laser lights with H2Ti3O7 NTs in the vicinity of lung and prostate cancer as two of the first frequent malignancy worldwide in male cancer with a significant increasing trend are in vitro investigated. The effects of various concentrations of bare H2Ti3O7 NTs at different incubation times in the presence and absence of laser light are investigated to estimate the effectiveness of the photodynamic therapy. Also, different laser wavelengths, laser intensities, and exposure times are applied to treat lung (A549 cells) and prostate (LNCap cells) treatment. The results indicated that H2Ti3O7 NTs can be an excellent candidate for the treatment of lung and prostate cancers and the reasons for the success of the treatment in dark and irradiated conditions are described in the paper.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13
Fig. 14

Similar content being viewed by others

Data availability

All data included in this paper are available upon request by contact with the corresponding author.

References

  • Abbaspoor, M., Aliannezhadi, M., Tehrani, F.S.: Effect of solution pH on as-synthesized and calcined WO3 nanoparticles synthesized using sol–gel method. Opt. Mater. 12, 111552 (2021)

  • Abbaspoor, M., Aliannezhadi, M., Tehrani, F.S.: High-performance photocatalytic WO3 nanoparticles for treatment of acidic wastewater. J. Sol Gel Sci. Technol. 105(2), 565–576 (2023)

    Article  Google Scholar 

  • Al-Awady, M.J., Greenway, G.M., Paunov, V.N.: Nanotoxicity of polyelectrolyte-functionalized titania nanoparticles towards microalgae and yeast: role of the particle concentration, size and surface charge. RSC Adv. 5(46), 37044–37059 (2015)

    Article  ADS  Google Scholar 

  • Al-Awady, M.J., et al.: Investigation of anti-MRSA and anticancer activity of eco-friendly synthesized silver nanoparticles from palm dates extract. Nano Biomed. Eng. 11(2), 157–169 (2019)

    Article  Google Scholar 

  • Alfaro, A., et al.: MgO nanoparticles coated with polyethylene glycol as carrier for 2-methoxyestradiol anticancer drug. PLoS ONE 14(8), e0214900 (2019)

  • Aliannezhadi, M., Minbashi, M., Tuchin, V.V.: Effect of laser intensity and exposure time on photothermal therapy with nanoparticles heated by a 793-nm diode laser and tissue optical clearing. Quantum Electron. 48(6), 559–564 (2018)

    Article  ADS  Google Scholar 

  • Aliannezhadi, M., Abbaspoor, M., Shariatmadar Tehrani, F., Jamali, M.: High photocatalytic WO3 nanoparticles synthesized using sol–gel method at different stirring times. Opt. Quantum Electron. 55(3), 250 (2023)

    Article  Google Scholar 

  • Al-Shreefy, H.H., Al-Awady, M.J., Al-Wasiti, E.: Characterization and cytotoxicity of novel synthesis selenium nanoparticles stabilized by vitamin E TPGS. J. Univ. Shanghai Sci. Technol. 24(2), 214–238 (2022). https://doi.org/10.51201/JUSST/22/0233

    Article  Google Scholar 

  • Arabeyyat, Z.H., Al-Awady, M.J., Greenway, G.M., Paunov, V.N., Rotchell, J.M.: Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos. SN Appl. Sci. 2, 1–12 (2020)

    Article  Google Scholar 

  • Bahadori, A., Dizaji, H.R., Memarian, N., Aliannezhadi, M.: Effect of preparation conditions on physical properties of manganese oxide thin films. J. Sol Gel Sci. Technol. 95, 180–189 (2020a)

    Article  Google Scholar 

  • Bahadori, A., Dizaji, H.R., Memarian, N., Aliannezhadi, M.: Effect of preparation conditions on physical properties of manganese oxide thin films. J. Sol Gel Sci. Technol. 95(1), 180–189 (2020b)

    Article  Google Scholar 

  • Caratão, B., Carneiro, E., Sá, P., Almeida, B., Carvalho, S.: Properties of electrospun TiO2 nanofibers. J. Nanotechnol. 2014, 1–5 (2014)

  • Çeşmeli, S., BirayAvci, C.: Application of titanium dioxide (TiO2) nanoparticles in cancer therapies. J. Drug Target. 27(7), 762–766 (2019)

    Article  Google Scholar 

  • Chang, Y.-C., Lin, J.-C., Chou, C.-M.: H2Ti3O7 nanowires as a high-performance photocatalytic and surface-enhanced Raman scattering substrate. J. Photochem. Photobiol. A Chem. 400, 112666 (2020)

  • Chatterjee, S., Tyagi, A.K., Ayyub, P.: Efficient photocatalytic degradation of rhodamine B dye by aligned arrays of self-assembled hydrogen titanate nanotubes. J. Nanomater. 2014, 36–36 (2014)

    Article  Google Scholar 

  • Feoktistova, M., Geserick, P., Leverkus, M.: Crystal violet assay for determining viability of cultured cells. Cold Spring Harb. Protoc. 2016(4), pdb.prot087379 (2016)

    Article  Google Scholar 

  • Gao, R., Huang, Y., Liu, D., Li, G.: Effect of heat treatment process on the structure and properties of nano-TiO2. Nat. Environ. Pollut. Technol. 20(1), 405–410 (2021)

    Article  Google Scholar 

  • García-Contreras, L.A., Flores-Flores, J.O., Arenas-Alatorre, J.Á., Chávez-Carvayar, J.Á.: Synthesis, characterization and study of the structural change of nanobelts of TiO2 (H2Ti3O7) to nanobelts with anatase, brookite and rutile phases. J. Alloys Compd. 923, 166236 (2022)

    Article  Google Scholar 

  • Geiseler, B., Miljevic, M., Müller, P., Fruk, L.J.: Phototriggered production of reactive oxygen species by TiO2 nanospheres and rods. J. Nanomater. 2012, 21 (2012)

    Article  Google Scholar 

  • Guo, G.-S., He, C.-N., Wang, Z.-H., Gu, F.-B., Han, D.-M.: Synthesis of titania and titanate nanomaterials and their application in environmental analytical chemistry. Talanta 72(5), 1687–1692 (2007)

    Article  Google Scholar 

  • Harada, A., Ono, M., Yuba, E., Kono, K.: Titanium dioxide nanoparticle-entrapped polyion complex micelles generate singlet oxygen in the cells by ultrasound irradiation for sonodynamic therapy. Biomater. Sci. 1(1), 65–73 (2013)

    Article  Google Scholar 

  • Hardcastle, F.: Raman spectroscopy of titania (TiO2) nanotubular water-splitting catalysts. J. Arkansas Acad. Sci. 65(1), 43–48 (2011)

    Google Scholar 

  • Jun, Y., Park, J.H., Kang, M.G.: The preparation of highly ordered TiO2 nanotube arrays by an anodization method and their applications. Chem. Commun. 48(52), 6456–6471 (2012)

    Article  Google Scholar 

  • Kanehira, K., et al.: Fluorescence enhancement effect of TiO2 nanoparticles and application for photodynamic diagnosis. Int. J. Mol. Sci. 20(15), 3698 (2019)

    Article  Google Scholar 

  • Kim, I.Y., Lee, T.G., Reipa, V., Heo, M.B.: Titanium dioxide induces apoptosis under UVA irradiation via the generation of lysosomal membrane permeabilization-dependent reactive oxygen species in HaCaT cells. Nanomaterials 11(8), 1943 (2021)

    Article  Google Scholar 

  • Lee, C., Hong, C., Kim, H., Kang, J., Zheng, H.M.: TiO2 nanotubes as a therapeutic agent for cancer thermotherapy. Photochem. Photobiol. 86(4), 981–989 (2010)

    Article  Google Scholar 

  • Lee, K., Mazare, A., Schmuki, P.: One-dimensional titanium dioxide nanomaterials: nanotubes. Chem. Rev. 114(19), 9385–9454 (2014)

    Article  Google Scholar 

  • Mahmoodi, N.O., Ghavidast, A., Amirmahani, N.: A comparative study on the nanoparticles for improved drug delivery systems. J. Photochem. Photobiol. B 162, 681–693 (2016)

    Article  Google Scholar 

  • Maira, A., Coronado, J., Augugliaro, V., Yeung, K., Conesa, J., Soria, J.: Fourier transform infrared study of the performance of nanostructured TiO2 particles for the photocatalytic oxidation of gaseous toluene. J. Catal. 202(2), 413–420 (2001)

    Article  Google Scholar 

  • Matoba, Y., Banno, K., Kisu, I., Aoki, D.: Clinical application of photodynamic diagnosis and photodynamic therapy for gynecologic malignant diseases: a review. Photodiagn. Photodyn. Ther. 24, 52–57 (2018)

    Article  Google Scholar 

  • Nam, C.T., Yang, W.-D., Le Minh, D.: Study on photocatalysis of TiO2 nanotubes prepared by methanol–thermal synthesis at low temperature. Bull. Mater. Sci. 36(5), 779–788 (2013)

    Article  Google Scholar 

  • Nowak, M., Kauch, B., Szperlich, P.: Determination of energy band gap of nanocrystalline SbSI using diffuse reflectance spectroscopy. Rev. Sci. Instrum. 80(4), 046107 (2009). https://doi.org/10.1063/1.3103603

    Article  ADS  Google Scholar 

  • Ramimoghadam, D., Bagheri, S., Abd Hamid, S.B.: Biotemplated synthesis of anatase titanium dioxide nanoparticles via lignocellulosic waste material. BioMed Res. Int. 2014, 1–7 (2014)

  • Rawla, P.: Epidemiology of prostate cancer. World J. Oncol. 10(2), 63–89 (2019)

    Article  Google Scholar 

  • Reznikov, A., Salivonyk, O., Sotkis, A., Shuba, Y.: Assessment of gold nanoparticle effect on prostate cancer LNCaP cells. Exp. Oncol. 37(2), 100–104 (2015)

  • Riley, P.J.: Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int. J. Radiat. Biol. 65(1), 27–33 (1994)

    Article  MathSciNet  Google Scholar 

  • Shajeelammal, J., Mohammed, S., Asok, A., Shukla, S.: Removal of methylene blue and azo reactive dyes from aqueous solution and textile effluent via modified pulsed low-frequency ultrasound cavitation process. Environ. Sci. Pollut. Res. 1–23 (2022)

  • Sheikhi, S., Aliannezhadi, M., Shariatmadar Tehrani, F.: Effect of precursor material, pH, and aging on ZnO nanoparticles synthesized by one-step sol–gel method for photodynamic and photocatalytic applications. Eur. Phys. J. plus 137(1), 60 (2021). https://doi.org/10.1140/epjp/s13360-021-02252-8

    Article  Google Scholar 

  • Sheikhi, S., Aliannezhadi, M., Tehrani, F.S.: The effect of PEGylation on optical and structural properties of ZnO nanostructures for photocatalyst and photodynamic applications. Mater. Today Commun. 34, 105103 (2023)

    Article  Google Scholar 

  • Sung, H., et al.: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71(3), 209–249 (2021)

    Article  Google Scholar 

  • Tehrani, F.S., Ahmadian, H., Aliannezhadi, M.: Hydrothermal synthesis and characterization of WO3 nanostructures: effect of reaction time. Mater. Res. Express 7(1), 015911 (2020)

    Article  ADS  Google Scholar 

  • Tehrani, F.S., Ahmadian, H., Aliannezhadi, M.: High specific surface area micro-mesoporous WO3 nanostructures synthesized with facile hydrothermal method. Eur. Phys. J. plus 136(1), 1–11 (2021)

    Google Scholar 

  • Terracciano, M., Galstyan, V., Rea, I., Casalino, M., De Stefano, L., Sbervegleri, G.: Chemical modification of TiO2 nanotube arrays for label-free optical biosensing applications. Appl. Surf. Sci. 419, 235–240 (2017)

    Article  ADS  Google Scholar 

  • Thevenot, P., Cho, J., Wavhal, D., Timmons, R.B., Tang, L.: Surface chemistry influences cancer killing effect of TiO2 nanoparticles. Nanomed. Nanotechnol. Biol. Med. 4(3), 226–236 (2008)

    Article  Google Scholar 

  • Vrchovecká, K., et al.: A release of Ti-ions from nanostructured titanium oxide surfaces. Surf. Interfaces 29, 101699 (2022)

    Article  Google Scholar 

  • Yajun, J.: Growth mechanism and photocatalytic performance of double-walled and bamboo-type TiO2 nanotube arrays. RSC Adv. 4(76), 40474–40481 (2014)

    Article  Google Scholar 

  • Yurt, F., et al.: Investigation of in vitro PDT activities of zinc phthalocyanine immobilised TiO2 nanoparticles. Int. J. Pharm. 524(1–2), 467–474 (2017)

    Article  Google Scholar 

  • Yurt, F., et al.: Photodynamic therapy and nuclear imaging activities of SubPhthalocyanine integrated TiO2 nanoparticles. J. Photochem. Photobiol. A 367, 45–55 (2018)

    Article  Google Scholar 

  • Zappa, C., Mousa, S.A.: Non-small cell lung cancer: current treatment and future advances. Transl. Lung Cancer Res. 5(3), 288–300 (2016)

    Article  Google Scholar 

  • Zhang, H., Shan, Y., Dong, L.: A comparison of TiO2 and ZnO nanoparticles as photosensitizers in photodynamic therapy for cancer. J. Biomed. Nanotechnol. 10(8), 1450–1457 (2014)

    Article  Google Scholar 

Download references

Funding

This research did not receive any specific grant from funding agencies.

Author information

Authors and Affiliations

  1. Faculty of Physics, Semnan University, PO Box: 35195-363, Semnan, Iran

    Maher I. Al-Shemri & Maryam Aliannezhadi

  2. Department of Biotechnology, College of Biotechnology, Al Qasim Green University, Babylon, Iraq

    Mohammed J. Al-Awady

  3. Department of Chemistry, Faculty of Science, University of Western Ontario, 1151 Richmond Street, London, ON, N6A 5B7, Canada

    Mohammed J. Al-Awady

  4. Department of Anatomy and Histology, College of Medicine, University of Babylon, Babylon, Iraq

    Rana A. Ghaleb

Authors
  1. Maher I. Al-Shemri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Maryam Aliannezhadi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mohammed J. Al-Awady
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rana A. Ghaleb
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

MA and MJA did Conceptualization and M IA, RAG, MA, and MJA did methodology, and RAG and MA applied software, and MJA, RAG, and MA investigated validation and MIA did formal analysis, M IA, RAG, MA, and MJA did the investigation, MA and RAG did data curation, MIA, RAG, MA, and MJA wrote the manuscript, MA, RAG, and MJA did the review and editing, and MA is the supervision of the project and RAG, MJA, and MA are project administration. All authors have read and agreed to the published version of the manuscript. Also, all authors reviewed the manuscript.

Corresponding author

Correspondence to Maryam Aliannezhadi.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

It is not applicable because the studies were done in vitro.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Al-Shemri, M.I., Aliannezhadi, M., Al-Awady, M.J. et al. Interaction of different lasers beams with synthesized H2Ti3O7 nanotubes: toward photodynamic therapy. Opt Quant Electron 55, 671 (2023). https://doi.org/10.1007/s11082-023-04977-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11082-023-04977-5

Keywords

Search

Navigation