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INAA of essential micronutrients in Terminalia arjuna bark powder: a versatile heart tonic

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Abstract

Five bark powder samples of Arjuna (Terminalia arjuna) having different origins including two commercial brands were analyzed for 8 minor (Al, Na, K, Mg, Ca, P, Cl, Fe) and 19 trace (As, Ba, Br, Co, Cr, Cs, Cu, Eu, Hg, La, Mn, Rb, Sb, Sc, Sm, Sr, Th, V, Zn) elements by INAA. Also concentrations of Ni, Cd and Pb were determined by AAS and of Sn by ICP-MS. Arjuna bark powder is enriched in Ca (34.1 ± 10.6 mg/g), Mg (5.41 ± 1.93 mg/g), K (5.87 ± 2.18 mg/g), Cl (4.0 ± 2.2 mg/g) and Fe (2.99 ± 1.77 mg/g) with significant amounts of Cr (6.9 ± 4.0 μg/g), Mn (75.5 ± 24.8 μg/g), Sr (114 ± 69 μg/g) and Zn (11.9 ± 8.9 μg/g). Several toxic elements such as As (78.6 ± 19.9 ng/g), Cd (5.60 ± 9.04 μg/g), Hg (69 ± 41 ng/g) and Pb (5.0 ± 3.5 μg/g) were also detected.

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References

  1. Paranjpe P (1999) Indian medicinal plants; forgotten healers. Chaukhamba Sanskrit Pratisthan, Delhi

    Google Scholar 

  2. Dwivedi S, Chopra D (2014) Revisiting Terminalia arjuna: an ancient cardiovascular drug. J Tradit Complement Med 4:224–231

    Article  Google Scholar 

  3. Chaudhari M, Mengi S (2006) Evaluation of phytoconstituents of Terminalia arjuna for wound healing activity in rats. Phytother Res 20:799–805

    Article  CAS  Google Scholar 

  4. Shivarajan VV, Balachandran I (1994) Ayurvedic drugs and their plant sources. Oxford & IBH Publishing Co Pvt. Ltd, New Delhi

    Google Scholar 

  5. Karthikeyan K, Bai BR, Gauthaman K, Sathish KS, Devraj SN (2003) Cardiovascular effect of the alcoholic extract of Terminalia arjuna bark in an in vivo model of myocardial ischemic reperfusion injury. Life Sci 73:2727–2739

    Article  CAS  Google Scholar 

  6. Mandal S, Patra A, Samanta A, Roy S, Mandal A, Mahapatra TD, Pradhan S, Das K, Nandi DK (2013) Analysis of phytochemical profile of Terminalia arjuna bark extract with antioxidative and antimicrobial properties. Asian Pac J Trop Biomed 3:960–966

    Article  CAS  Google Scholar 

  7. Devi RS, Narayan S, Vani G, Shyamala Devi CS (2007) Gastroprotective effect of Terminalia arjuna bark on diclofenac sodium induced gastric ulcer. Chem Biol Interact 167:71–83

    Article  CAS  Google Scholar 

  8. Scassellati-Sforzolini G, Villarini LM, Moretti LM, Marcarelli LM, Pasquini R, Fatigoni C, Kaur LS, Kumar S, Grover IS (1999) Antigenotoxic properties of Terminalia arjuna bark extracts. J Environ Pathol Toxicol Oncol 18:119–125

    CAS  Google Scholar 

  9. Bharani A, Ahirwar LK, Jain N (2004) Terminalia arjuna reverses impaired endothelial function in chronic smokers. Indian Heart J 56:23–128

    Google Scholar 

  10. O’Dell BL, Sunde RA (eds) (1997) Handbook of nutritionally essential mineral elements. Marcel Dekker Inc., New York

  11. Ebrahim AM, Etayeb MA, Khalid H, Noun M, Roumie M, Michalke B (2014) PIXE as a complement to ICP-OES trace metal analysis in Sudanese medicinal plants. Appl Radiat Isot 90:218–224

    Article  Google Scholar 

  12. Singh DV, Gupta MM, Tripathi AK, Prajapati V, Kumar S (2004) Arjunetin from Terminalia arjuna as an insect feeding deterrent and growth inhibitor. Phytother Res 18:131–134

    Article  CAS  Google Scholar 

  13. Ali A, Kaur G, Hayat K, Ali M, Athar M (2003) A novel naphthanol glycoside from Terminmalia arjuna with antioxidant and nitric oxide inhibitory activities. Pharmazie 58:932–934

    CAS  Google Scholar 

  14. Muhammad S, Khan BA, Akhtar N, Mahmood T, Rasul A, Hussain I, Khan H, Badshah A (2012) The morphology, extractions, chemical constituents and uses of Terminalia arjuna: a review. J Med Plants Res 6:4772–4775

    Google Scholar 

  15. Singh V, Garg AN (1996) Availability of essential trace elements in Ayurvedic Indian medicinal herbs using instrumental activation analysis. Appl Radiat Isot 48:97–101

    Article  Google Scholar 

  16. Kumar A, Nair AGC, Reddy AVR, Garg AN (2005) Analysis of essential elements in Prgya-peya-a herbal drink and its constituents by neutron activation. J Pharm Biomed Anal 37:631–638

    Article  CAS  Google Scholar 

  17. Patil UH, Gaikwad DK (2011) Inorganic constituents of stem bark of Terminalia Arjuna. Int J Adv Pharm Res 2:281–285

    Google Scholar 

  18. Dutta RK, Maharia RS, Acharya R, Reddy AVR (2014) Analysis of bioaccessible concentration of trace elements in plant based edible materials by INAA and ICPMS methods. J Radioanal Nucl Chem 300:185–189

    Article  CAS  Google Scholar 

  19. Choudhury RP, Garg AN (2007) Variation in essential, trace and toxic elemental contents in Murraya Koenigi: a spice and medicinal herb from different Indian states. Food Chem 104:1454–1463

    Article  CAS  Google Scholar 

  20. Garg AN, Kumar A, Choudhury RP (2007) Phosphorus in biological standards and samples by thermal neutron irradiation and â counting. J Radioanal Nucl Chem 271:481–488

    Article  CAS  Google Scholar 

  21. Dybczynski R, Danko B, Kulisa K, Masleszewska E, Polkowska-Motrenko H, Samczynski Z, Szopa Z (2004) Preparation and preliminary certification of two new CRMs for inorganic trace analysis. J Radioanal Nucl Chem 259:409–413

    Article  CAS  Google Scholar 

  22. Certificate of Analysis (1993) Peach Leaves (SRM-1547) National Institute of Standards and Technology, USA

  23. Garg AN, Verma K (2012) Radioisotopes in chemical research: neutron activation analysis of leaves and bark of neem. Asian J Chem 24:5435–5440

    CAS  Google Scholar 

  24. Sigel A, Sigel H, Sigel RKO (eds) (2013) Interrelations between essential metal ions and human diseases, vol 13. Springer, Heidelberg

    Google Scholar 

  25. Slotki I (2005) Intravenous iron supplementation in the anaemia of renal and cardiac failure-a double edged sword. Nephrol Dial Transplant 20:16–23

    Article  Google Scholar 

  26. Zaidi JH, Fatima I, Qureshi IH, Subhani MS (2004) Trace element evaluation of some medicinal herbs by instrumental neutron activation analysis. Radiochim Acta 92:363–368

    CAS  Google Scholar 

  27. Thompson KH, Lee M (1993) Effect of manganese and vitamin E deficiencies on antioxidant enzymes in streptozotocin diabetic rats. J Nutr Biochem 4:476–481

    Article  CAS  Google Scholar 

  28. Sultana B, Anwar F, Przyblski R (2007) Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia arjuna. Acacia nilotica and Eugenia jambolana Lam trees. Food Chem 104:1106–1114

    Article  CAS  Google Scholar 

  29. Saper RB, Kales SN, Paquin J, Burns MJ, Eisenberg DM, Davis RB, Phillips RS (2004) Heavy metal contents of Ayurvedic herbal medicine products. J Am Med Assoc 292:2868–2873

    Article  CAS  Google Scholar 

  30. Siddiqui R, Vohora SB (2000) Analgesic activity of arsenic preparations used in Unani tibb. Indian Drugs 37:274–278

    CAS  Google Scholar 

  31. Vohora SB, Kim HS, Shah SA, Khanna T, Dandiya PC (1995) In: Abdulla M, Vohora SB, Athar M (eds) Trace and toxic elements in nutrition and health. Wiley Eastern Limited, New Delhi, pp 73–80

    Google Scholar 

  32. Puga AP, Abreu CA, Melo LC, Paz-Ferreiro J, Beesley L (2015) Cadmium, lead, and zinc mobility and plant uptake in a mine soil amended with sugarcane straw biochar. Environ Sci Pollut Res Int 22:17606–17614

    Article  CAS  Google Scholar 

  33. Maharia RS, Dutta RK, Acharya R, Reddy AVR (2010) Heavy metal bioaccumulation in selected medicinal plants collected from Khetri copper mines and comparison with those collected from fertile soil in Haridwar, India. J Environ Sci Health Part B 45:174–181

    Article  CAS  Google Scholar 

  34. Lopez E, Figueroa S, Oset-Gasque MJ, Gonzalez MP (2003) Apoptosis and necrosis: two distinct events induced by cadmium in cortical neurons in culture. Br J Pharmacol 138:901–911

    Article  CAS  Google Scholar 

  35. Alia N, Sardar K, Said M, Salma K, Sadia A, Sadaf S, Toqeer A, Miklas S (2015) Toxicity and bioaccumulation of heavy metals in spinach (Spinacia oleracea) grown in a controlled environment. Int J Environ Res Public Health 12:7400–7416

    Article  CAS  Google Scholar 

  36. Chan K (2003) Some aspects of toxic contaminants in herbal medicines. Chemosphere 52:1361–1371

    Article  CAS  Google Scholar 

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Acknowledgements

Grateful thanks are due to the Board of Research in Nuclear Sciences, Government of India for financial assistance (2000/37/5/BRNS) and to MHRD for fellowships to PTG and RPC. Sincere thanks are due to Drs. A V R Reddy and R Acharya, Radiochemistry Division, BARC for providing necessary counting facilities and help during short irradiation work. Sincere thanks to Dr Arpita Datta for her help.

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Garg, A.N., Gajbhiye, P.T. & Choudhury, R.P. INAA of essential micronutrients in Terminalia arjuna bark powder: a versatile heart tonic. J Radioanal Nucl Chem 314, 1539–1545 (2017). https://doi.org/10.1007/s10967-017-5564-8

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  • DOI: https://doi.org/10.1007/s10967-017-5564-8

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