SpringerLink
Log in

Phytosynthesis, Characterization and Fungicidal Potential of Emerging Gold Nanoparticles Using Pongamia pinnata Leave Extract: A Novel Approach in Nanoparticle Synthesis

  • Original Paper
  • Published:
Journal of Cluster Science Aims and scope Submit manuscript

Abstract

Biomediated synthesis of gold nanoparticles (AuNPs) using plant extract is a favorable alternative to traditional physicochemical based methods. Biological synthesis assists in the generation of stable and biocompatible nanoparticles (NPs). The aim of the present work was to fabricate AuNPs using Pongamia pinnata leave extract. The synthesized AuNPs were characterized by various analytical techniques such as UV–visible spectroscopy, TEM, EDX, and XRD. Absorption spectra showed SPR peaks in the range of 520–540 nm signifying the formation of AuNPs stabilized by P. pinnata extract. The average size of NPs was found in the range 10–25 nm as obtained from TEM analysis. Moreover, the synthesized NPs showed antifungal activity. The antifungal activities of AuNPs were tested against oomycetes SR1 and BP1120. The MIC80 value was observed at the concentrations 1.6 and 0.8 mg/mL of AuNPs in SR1 and BP1120 fungus, respectively. The study revealed an efficient, eco-friendly and simple method for synthesis of stable AuNPs using green synthetic approach.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Germany)

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. C. T. Laurencin, S. G. Kumbar, and S. P. Nukavarapu (2009). Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol.1, 6.

    Article  CAS  Google Scholar 

  2. H. Barabadi, F. Kobarfard, and H. Vahidi (2018). Iran J. Pharm. Res.17, 87.

    CAS  PubMed  PubMed Central  Google Scholar 

  3. H. Barabadi (2017). Cell. Mol. Biol.63, 3.

    Article  Google Scholar 

  4. S. Ahmed, M. Ahmad, B. L. Swami, and S. Ikram (2016). J. Adv. Res.7, 17.

    Article  CAS  Google Scholar 

  5. Q. Abbas, M. Saleem, A. R. Phull, M. Rafiq, M. Hassan, K.-H. Lee, and S.-Y. Seo (2017). Iran J. Pharm. Res.16, 760.

    CAS  Google Scholar 

  6. R. Dobrucka (2017). Iran J. Pharm. Res.16, 753.

    CAS  Google Scholar 

  7. N. Karimi, A. Chardoli, and A. Fattahi (2017). Iran J. Pharm. Res.16, 1167.

    PubMed  PubMed Central  Google Scholar 

  8. M. M. Or Rashid, M. S. Islam, M. A. Haque, M. A. Rahman, M. T. Hossain, and M. A. Hamid (2016). Iran J. Pharm. Res.15, 591.

    PubMed  PubMed Central  Google Scholar 

  9. S. Salari, S. Esmaeilzadeh Bahabadi, A. Samzadeh-Kermani, and F. Yousefzaei (2019). Iran J. Pharm. Res.18, 430.

    CAS  PubMed  PubMed Central  Google Scholar 

  10. T. Ramezani, M. Nabiuni, J. Baharara, K. Parivar, and F. Namvar (2019). Iran J. Pharm. Res.18, 222.

    CAS  PubMed  PubMed Central  Google Scholar 

  11. M. Maham and R. Karami-Osboo (2017). Iran J. Pharm. Res.16, 462.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Z. Rezvani Amin, Z. Khashyarmanesh, B. S. Fazly Bazzaz, and Z. Sabeti Noghabi (2019). Iran J. Pharm. Res.18, 210.

    PubMed  PubMed Central  Google Scholar 

  13. H. Barabadi, B. Tajani, M. Moradi, K. Damavandi Kamali, R. Meena, S. Honary, M. A. Mahjoub, and M. Saravanan (2019). J. Clust. Sci.. https://doi.org/10.1007/s10876-019-01554.

    Article  Google Scholar 

  14. S. Honary, H. Barabadi, P. Ebrahimi, F. Naghibi, and A. Alizadeh (2015). J. Nano Res.30, 106.

    Article  CAS  Google Scholar 

  15. H. Barabadi and S. Honary (2016). Pharm. Biomed. Res.2, 1.

    Google Scholar 

  16. M. Saravanan, S. Arokiyaraj, T. Lakshmi, and A. Pugazhendhi (2018). Microb. Pathog.117, 68.

    Article  CAS  Google Scholar 

  17. S. A. Dahoumane, M. Mechouet, K. Wijesekera, C. D. M. Filipe, C. Sicard, D. A. Bazylinski, and C. Jeffryes (2017). Green Chem.19, 552.

    Article  CAS  Google Scholar 

  18. M. Faraday (1857). Lond. Edinb. Dubl. Philos. Mag.14, 512.

    Article  Google Scholar 

  19. A. Nel, T. **a, L. Madler, and N. Li (2006). Science311, 622.

    Article  CAS  Google Scholar 

  20. R. A. Sperling, P. Rivera Gil, F. Zhang, M. Zanella, and W. J. Parak (2008). Chem. Soc. Rev.37, 1896.

    Article  CAS  Google Scholar 

  21. M. Ovais, A. T. Khalil, A. Raza, M. A. Khan, I. Ahmad, N. U. Islam, M. Saravanan, M. F. Ubaid, M. Ali, and Z. K. Shinwari (2016). Nanomedicine (Lond.)11, 3157.

    Article  CAS  Google Scholar 

  22. R. K. Singh, G. Nath, S. B. Acharya, and R. K. Goel (1997). Indian J. Exp. Biol.35, 831.

    CAS  PubMed  Google Scholar 

  23. R. Sankaranarayanan and J. Ferlay (2006). Best. Pract. Res. Clin. Obstet. Gynaecol.20, 207.

    Article  CAS  Google Scholar 

  24. N. Munoz, F. X. Bosch, S. de Sanjose, R. Herrero, X. Castellsague, K. V. Shah, P. J. Snijders, and C. J. Meijer (2003). N. Engl. J. Med.348, 518.

    Article  Google Scholar 

  25. R. K. Singh, V. K. Joshi, R. K. Goel, S. S. Gambhir, and S. B. Acharya (1996). Indian J. Exp. Biol.34, 1204.

    CAS  PubMed  Google Scholar 

  26. T. S. Ramakrishnan and C. K. Sowmini (1955). Indian Phytopath.7, 152.

    Google Scholar 

  27. C. Ushamalini, P. Nakkeeran, and T. Marimuthu (2008). Arch. Phytopathol. Plant Protect.41, 79.

    Article  CAS  Google Scholar 

  28. N. Radhakrishnan and R. Balasubramanian (2009). Crop Protect.28, 974.

    Article  CAS  Google Scholar 

  29. C. Kole, P. Kole, K. M. Randunu, P. Choudhary, R. Podila, P. C. Ke, A. M. Rao, and R. K. Marcus (2013). BMC Biotechnol.13, 37.

    Article  Google Scholar 

  30. F. Ghazizadeh, S. Ghaffari, S. F. Mirshojaei, M. Mazidi, and S. Azarmi (2018). Iran J. Pharm. Res.17, 1209.

    CAS  PubMed  PubMed Central  Google Scholar 

  31. H. Sobhani, P. Tarighi, S. N. Ostad, A. Shafaati, N. Nafissi-Varcheh, and R. Aboofazeli (2018). Iran J. Pharm. Res.17, 830.

    CAS  PubMed  PubMed Central  Google Scholar 

  32. G. M. L. Consoli, G. Granata, R. Picciotto, A. R. Blanco, C. Geraci, A. Marino, and A. Nostro (2018). Medchemcomm9, 160.

    Article  CAS  Google Scholar 

  33. H. E. Karahan, L. Wei, K. Goh, Z. Liu, O. Birer, F. Dehghani, C. Xu, J. Wei, and Y. Chen (2016). Nanoscale8, 17181.

    Article  CAS  Google Scholar 

  34. W. Haiss, N. T. Thanh, J. Aveyard, and D. G. Fernig (2007). Anal. Chem.79, 4215.

    Article  CAS  Google Scholar 

  35. C. Karuppiah, S. Palanisamy, S.-M. Chen, R. Emmanuel, K. Muthupandi, and P. Prakash (2015). RSC Adv.5, 16284.

    Article  CAS  Google Scholar 

  36. G. Frens (1973). Nat. Phys. Sci.241, 20.

    Article  CAS  Google Scholar 

  37. S. Park, H. Chibli, J. Wong, and J. L. Nadeau (2011). Nanotechnology22, 185101.

    Article  Google Scholar 

  38. S. Nath, C. Kaittanis, A. Tinkham, and J. M. Perez (2008). Anal. Chem.80, 1033.

    Article  CAS  Google Scholar 

  39. S. Ray, R. Mohan, J. K. Singh, M. K. Samantaray, M. M. Shaikh, D. Panda, and P. Ghosh (2007). J. Am. Chem. Soc.129, 15042.

    Article  CAS  Google Scholar 

  40. R. Langer and D. A. Tirrell (2004). Nature428, 487.

    Article  CAS  Google Scholar 

  41. T. M. Allen and P. R. Cullis (2004). Science303, 1818.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors are grateful to AIRF, JNU for analytical characterization. EP is grateful to DST-SERB for fellowship under National Postdoctoral Scheme (Grant Number: PDF/2017/0024). We thank our colleague Dr. Usha Singh and other colleagues who provided insight and expertise that greatly assisted the research, this study was supported by grants from the project Boron capture therapy in cancer diagnosis.

Author information

Authors and Affiliations

  1. School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India

    Ashapurna Khatua, Eepsita Priyadarshini, Paulraj Rajamani, Abhinav Prasad, llora Ghosh & Ramovatar Meena

  2. Institute Jules Guyot, Universite de Bourgogne, Dijon, France

    Bernard Paul

  3. School of Biotechnology and Bioinformatics, Sambalpur University, Sambalpur, Odisha, India

    Amiyakumar Patel & Aparupa Naik

  4. Baba Haridas College of Pharmacy and Technology, Jharodha Kalan, New Delhi, 110072, India

    Jitender Kumar

  5. Department of Medical Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Sciences, Mekelle University, Tigray, Ethiopia

    Muthupandian Saravanan

  6. School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Hamed Barabadi

Authors
  1. Ashapurna Khatua
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eepsita Priyadarshini
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Paulraj Rajamani
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Amiyakumar Patel
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jitender Kumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Aparupa Naik
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Muthupandian Saravanan
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Hamed Barabadi
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Abhinav Prasad
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. llora Ghosh
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Bernard Paul
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Ramovatar Meena
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Muthupandian Saravanan or Ramovatar Meena.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Khatua, A., Priyadarshini, E., Rajamani, P. et al. Phytosynthesis, Characterization and Fungicidal Potential of Emerging Gold Nanoparticles Using Pongamia pinnata Leave Extract: A Novel Approach in Nanoparticle Synthesis. J Clust Sci 31, 125–131 (2020). https://doi.org/10.1007/s10876-019-01624-6

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10876-019-01624-6

Keywords

Search

Navigation