SpringerLink
Log in

Surface modification of YAG:Ce3+ nanoparticles by poly(acrylic acid) and their biological application

  • Published:
Journal of Materials Science Aims and scope Submit manuscript

Abstract

Yttrium aluminum garnet Y3Al5O12 (YAG):Ce3+ nanoparticles prepared by glycothermal method are modified with poly(acrylic acid) (PAA). This surface modification enables YAG:Ce3+ nanoparticles to be well dispersed in phosphate-buffered saline (PBS) without any serious aggregation. YAG:Ce3+ nanoparticles emit yellowish green light under the excitation of blue light. This fluorescent property does not change after the modification of PAA. Streptavidin (SA) is immobilized on the surface of PAA-modified YAG:Ce3+ nanoparticles by using carboxyl groups of PAA as cross-linking sites. We demonstrate the quantitative analysis of bovine serum albumin in PBS by SA-immobilized YAG:Ce3+ nanoparticles.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (France)

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10

Similar content being viewed by others

References

  1. Bruchez M Jr, Moronne M, Gin P, Weiss S, Alivisatos AP (1998) Science 281:2013

    Article  CAS  Google Scholar 

  2. Chan WCW, Nie S (1998) Science 281:2016

    Article  CAS  Google Scholar 

  3. Dubertret B, Skourides P, Norris DJ, Noireaux V, Brivanlou AH, Libchaber A (2002) Science 298:1759

    Article  CAS  Google Scholar 

  4. Wu X, Liu H, Liu J, Haley KN, Treadway JA, Larson JP, Ge N, Peale F, Bruchez MP (2002) Nat Biotechnol 21:41

    Article  Google Scholar 

  5. Hanaki K, Momo A, Oku T, Komoto A, Maenosono S, Yamaguchi Y, Yamamoto K (2003) Biochem Biophys Res Commun 302:496

    Article  CAS  Google Scholar 

  6. Sukhanova A, Devy J, Venteo L, Kaplan H, Artemyev M, Oleinikov V, Klinov D, Pluot M, Cohen JHM, Nabiev I (2004) Anal Biochem 324:60

    Article  CAS  Google Scholar 

  7. Chen F, Gerion D (2004) Nano Lett 4:1827

    Article  CAS  Google Scholar 

  8. Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Science 307:538

    Article  CAS  Google Scholar 

  9. Beaurepaire E, Buissette V, Sauviat MP, Giaume D, Lahlil K, Mercuri A, Casanova D, Huignard A, Martin JL, Gacoin T, Boilot JP, Alexandrou A (2004) Nano Lett 4:2079

    Article  CAS  Google Scholar 

  10. Mattoussi H, Mauro JM, Goldman ER, Anderson GP, Sunder VC, Mikulec VM, Bawendi MG (2000) J Am Chem Soc 122:12142

    Article  CAS  Google Scholar 

  11. Goldman ER, Clapp AR, Anderson GP, Uyeda HT, Mauro JM, Medintz IL, Mattoussi H (2004) Anal Chem 76:684

    Article  CAS  Google Scholar 

  12. Gordon WO, Carter JA, Tissue BM (2004) J Lumin 108:339

    Article  CAS  Google Scholar 

  13. Yi G, Lu H, Zhao S, Ge Y, Yang W, Chen D, Guo LH (2004) Nano Lett 4:2191

    Article  CAS  Google Scholar 

  14. Yang W, Zhang CG, Qu HY, Yang HH, Xu JG (2004) Anal Chem Acta 503:163

    Article  CAS  Google Scholar 

  15. Huand CP, Liu HW, Tsao CY, Yin LT, Chiu SF, Chen TM (2005) Sens Actuators B 108:713

    Article  Google Scholar 

  16. Shen J, Sun LD, Yan CH (2008) Dalton Trans 5687

  17. Escudero A, Calvo ME, Rivera-Fernández S, de la Fuente JM, Ocana M (2013) Langmuir 29:1985

    Article  CAS  Google Scholar 

  18. Dembski S, Milde M, Dyrba M, Schweizer S, Gellermann C, Klockenbring T (2011) Langmuir 27:14025

    Article  CAS  Google Scholar 

  19. Al-Kattan A, Dufour P, Dexpert-Ghys J, Drouet C (2010) J Phys Chem C 114:2918

    Article  CAS  Google Scholar 

  20. Shen J, Sun LD, Zhu JD, Wei LH, Sun HF, Yan CH (2010) Adv Funct Mater 20:3708

    Article  CAS  Google Scholar 

  21. Chen YC, Wu YC, Wang DY, Chen TM (2012) J Mater Chem 22:7961

    Article  CAS  Google Scholar 

  22. Wang HF, Li Y, Wu YY, He Y, Yan XP (2010) Chem Eur J 16:12988

    Article  CAS  Google Scholar 

  23. He Y, Wang HF, Yan XP (2008) Anal Chem 80:3832

    Article  CAS  Google Scholar 

  24. Meiser F, Cortez C, Caruso F (2004) Angew Chem Int Ed 43:5954

    Article  CAS  Google Scholar 

  25. Kasuya R, Isobe T, Kuma H, Katano J (2005) J Phys Chem B 109:22126

    Article  CAS  Google Scholar 

  26. Kasuya R, Isobe T, Kuma H (2006) J Alloy Compd 408–412:820

    Article  Google Scholar 

  27. Asakura R, Isobe T, Kurokawa K, Aizawa H, Ohkubo M (2006) Anal Bioanal Chem 386:1641

    Article  CAS  Google Scholar 

  28. Tsukamoto A, Isobe T (2009) J Mater Sci 44:1344. doi:10.1007/s10853-008-3012-4

    Article  CAS  Google Scholar 

  29. Marchal J, John T, Baranwal R, Hinklin T, Laine RM (2004) Chem Mater 16:822

    Article  CAS  Google Scholar 

  30. Uvdal K, Bodo P, His A, Liedberg B, Salaneck WR (1990) J Colloid Interface Sci 140:207

    Article  CAS  Google Scholar 

  31. Santhiya D, Subramanian S, Natarajan KA, Malghan SG (1999) J Colloid Interface Sci 216:143

    Article  CAS  Google Scholar 

  32. Simon-Kutscher J, Gericke A, Hühnerfuss H (1996) Langmuir 12:1027

    Article  CAS  Google Scholar 

  33. Yamaguchi O, Takeoka K, Hirota K, Takano H, Hayashida A (1992) J Mater Sci 27:1261. doi:10.1007/BF01142034

    Article  CAS  Google Scholar 

  34. Lu CH, Hong HC, Jagannathan R (2002) J Mater Chem 12:2525

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223-8522, Japan

    Ryo Asakura & Tetsuhiko Isobe

Authors
  1. Ryo Asakura
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tetsuhiko Isobe
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tetsuhiko Isobe.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Asakura, R., Isobe, T. Surface modification of YAG:Ce3+ nanoparticles by poly(acrylic acid) and their biological application. J Mater Sci 48, 8228–8234 (2013). https://doi.org/10.1007/s10853-013-7634-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10853-013-7634-9

Keywords

Search

Navigation