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Effect of β-endorphin on production of antibodies and IL-4 under conditions of opioid receptor blockade

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Abstract

β-Endorphin in vivo produced different effects on antibody production depending on the administered dose. Blockade of opioid receptors with naloxone (but not naltrindole) abolished the effects of β-endorphin. The peptide activated IL-4 production in vitro via activation of δ-opioid receptors.

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Correspondence to S. V. Gein.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 8, pp. 192–195, August, 2006

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Gein, S.V., Baeva, T.A. & Kichanova, O.A. Effect of β-endorphin on production of antibodies and IL-4 under conditions of opioid receptor blockade. Bull Exp Biol Med 142, 226–229 (2006). https://doi.org/10.1007/s10517-006-0334-6

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  • DOI: https://doi.org/10.1007/s10517-006-0334-6

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