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Ultrastructural Study of Chitosan Effects on Klebsiella and Staphylococci

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Abstract

Antibacterial effect of chitosan on the morphofunctional organization of clinical strains of Klebsiella pneumoniae and Staphylococcus aureus was studied by transmission electron microscopy. Chitosan promoted aggregation of bacterial cells and disorganization of bacterial cell wall and cytoplasmic membrane, which leads to the release of bacterial contents into the environment. These structural changes result in bacterial death.

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Authors and Affiliations

  1. Laboratory of Microorganism Anatomy, N. F. Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Russia

    L. V. Didenko, N. D. Konstantinova & T. A. Silkina

  2. Laboratory of Enzyme Engineering, Bioengineering Center, Russian Academy of Sciences, Moscow, Russia

    D. V. Gerasimenko, I. D. Avdienko, G. E. Bannikova & V. P. Varlamov

Authors
  1. L. V. Didenko
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  2. D. V. Gerasimenko
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  3. N. D. Konstantinova
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  4. T. A. Silkina
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  5. I. D. Avdienko
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  6. G. E. Bannikova
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  7. V. P. Varlamov
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 9, pp. 343–347, September, 2005

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Didenko, L.V., Gerasimenko, D.V., Konstantinova, N.D. et al. Ultrastructural Study of Chitosan Effects on Klebsiella and Staphylococci. Bull Exp Biol Med 140, 356–360 (2005). https://doi.org/10.1007/s10517-005-0489-6

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  • DOI: https://doi.org/10.1007/s10517-005-0489-6

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