Abstract
Data on local epidemiology is necessary when deciding on the introduction of a vaccine. Parents of children attending 1st and 6th grades completed a questionnaire on demographical data and varicella history. Analyzing 70,226 questionnaires, varicella was reported in 63.6% and 78.6% of 1st and 6th grade children, respectively (mean age 4.75 years), indicating that a quarter of children entering adolescence are susceptible. Children attending day care and children with older siblings had contracted chickenpox at a younger age. In conclusion, in Greece, in addition to introducing universal varicella vaccination, it is necessary to identify older children at risk and offer catchup vaccination.
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs10096-007-0418-x/MediaObjects/10096_2007_418_Fig1_HTML.gif)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs10096-007-0418-x/MediaObjects/10096_2007_418_Fig2_HTML.gif)
Similar content being viewed by others
References
Arvin AM (2000) Varicella zoster virus. In: Behrman R, Kliegman R, Jensen H (eds) Nelson textbook of pediatrics, 15th edn. WB Saunders, Philadelphia, Pennsylvania, pp 1413–1418
Seward JF (2001) Update on varicella. Pediatr Infect Dis J 20:619–621
Coplan P, Black S, Rojas C, Shinefield H, Ray P, Lewis E, Guess H (2001) Incidence and hospitalization rates of varicella and herpes zoster before varicella vaccine introduction: a baseline assessment of the shifting epidemiology of varicella disease. Pediatr Infect Dis J 20:641–645
Centers for Disease Control and Prevention (1999) Prevention of varicella. Update recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 48(RR-6):1–5
Vinzio S, Lioure B, Goichot B (2006) Varicella in immunocompromised patients. Lancet 23(368):2208
Mullooly JP, Riedlinger K, Chun C, Weinmann S, Houston H (2005) Incidence of herpes zoster, 1997–2002. Epidemiol Infect 133:245–253
Weaver BA (2007) The burden of herpes zoster and postherpetic neuralgia in the United States. J Am Osteopath Assoc 107(Suppl 1):S2–S7
Pinot de Moira A, Nardone A; ESEN2 group (2005) Varicella zoster virus vaccination policies and surveillance strategies in Europe. Euro Surveill 10:43–45
Committee on Infectious Diseases (1995) Live attenuated varicella vaccine. Pediatrics 95:761–766
Nguyen HQ, Jumaan AO, Seward JF (2005) Decline in mortality due to varicella after implementation of varicella vaccination in the United States. N Engl J Med 352:450–458
Vazeou TH et al (2000) Decrease in age of varicella infection in Greek children, 1989–1997. In: Proceedings of the 38th National Pediatric Conference, Greece
Rentier B, Gershon AA; European Working Group on Varicella (EuroVar) (2004) Consensus: varicella vaccination of healthy children—a challenge for Europe. Pediatr Infect Dis J 23:379–389
Nadone A et al (2007) The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region. Vaccine 25(45):7866–7872
Meyer PA, Seward JF, Jumaan AO, Wharton M (2000) Varicella mortality: trends before vaccine licensure in the United States, 1970–1994. J Infect Dis 182:383–390
Gabutti G, Penna C, Rossi M, Salmaso S, Rota MC, Bella A, Crovari P; Serological Study Group (2001) The seroepidemiology of varicella in Italy. Epidemiol Infect 126:433–440
Acknowledgments
We would like to thank all of the teachers who voluntarily participated in this study and took the time to distribute the questionnaires, reinforce their completion, and collected and sent them back to us. We would also like to thank Vianex for supporting us financially for the postal expenses.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Katsafadou, A., Ferentinos, G., Constantopoulos, A. et al. The epidemiology of varicella in school-aged Greek children before the implementation of universal vaccination. Eur J Clin Microbiol Infect Dis 27, 223–226 (2008). https://doi.org/10.1007/s10096-007-0418-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10096-007-0418-x