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Chemical profiles and hypoglycemic activities of mulberry leaf extracts vary with ethanol concentration

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Abstract

Five mulberry leaf extracts (water, 25, 50, 75, and 100% EtOH) were characterized for in vitro hypoglycemic activity and chemical profiles. According to chemical profiles obtained from 15Tesla Fourier transform ion cyclotron resonance mass spectrometry, water extracts contained more 1-deoxynojirimycin (DNJ) and fewer phytochemicals than other extracts. However, water extracts showed the highest inhibitory activity of glucose uptake. The degree of inhibition of α-glucosidase activity was similar for all extracts. The effect of mulberry leaf extracts on the glucose metabolism may be attributed to additional or cooperative effects of DNJ with other phytochemical compounds.

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Authors and Affiliations

  1. Department of Food Science and Technology, Seoul National University of Science and Technology, Seoul, 120-750, Korea

    Ji Yeon Kim

  2. Department of Nutritional Science and Food Management, Ewha Womans University, Seoul, 120-750, Korea

    Hye In Chung & Oran Kwon

  3. Jeonnam Biofood Technology Center, Jeonnam, 520-330, Korea

    Kyeong-Ok Jung & Ji-Hyang Wee

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  1. Ji Yeon Kim
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  2. Hye In Chung
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  3. Kyeong-Ok Jung
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  4. Ji-Hyang Wee
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  5. Oran Kwon
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Correspondence to Oran Kwon.

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Kim, J.Y., Chung, H.I., Jung, KO. et al. Chemical profiles and hypoglycemic activities of mulberry leaf extracts vary with ethanol concentration. Food Sci Biotechnol 22, 1–5 (2013). https://doi.org/10.1007/s10068-013-0235-1

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  • DOI: https://doi.org/10.1007/s10068-013-0235-1

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