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Magnetic nanoparticles modified with polydimethylsiloxane and multi-walled carbon nanotubes for solid-phase extraction of fluoroquinolones

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Abstract

We have surface-functionalized magnetic particles (MPs) with polydimethylsiloxane and multi-walled carbon nanotubes in a two-step reaction. The MPs were applied to solid-phase extraction of the fluoroquinolones ofloxacin, norfloxacin, ciprofloxacin, enrofloxacin prior to their determination by capillary liquid chromatography. The effects of sample pH, adsorption time, type of eluent, desorption time and desorption temperature were investigated. Under the optimum conditions, the extraction efficiencies are in the range from 81.5 % to 94.1 %, with relative standard deviations (RSDs) of <7.6 %. The detection limits vary from 0.24 to 0.48 ng mL−1. The method was applied to the analysis of spiked mineral water and honey. The recoveries for the fluoroquinolones in the real samples range from 84.0 % to 112 %, with RSDs ranging from 2.9 % to 7.8 %.

 

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Acknowledgments

This work was supported by the National Natural Science Foundation of China (No. 21075044, 21175048).

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Authors and Affiliations

  1. Ministry of Education Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, 510631, China

    Shen Xu, Cheng Jiang, Yuexin Lin & Li Jia

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  1. Shen Xu
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  2. Cheng Jiang
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  4. Li Jia
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Correspondence to Li Jia.

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Xu, S., Jiang, C., Lin, Y. et al. Magnetic nanoparticles modified with polydimethylsiloxane and multi-walled carbon nanotubes for solid-phase extraction of fluoroquinolones. Microchim Acta 179, 257–264 (2012). https://doi.org/10.1007/s00604-012-0894-2

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  • DOI: https://doi.org/10.1007/s00604-012-0894-2

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