Abstract
ABO is the most important blood group system in transfusion and transplantation practices. Glycosyltransferases are controlled by the ABO system which is helpful in building oligosaccharide structures on the cell surface of erythrocytes and vascular endothelium and in the exocrine secretion system, including the respiratory tract. We analyzed the ABO blood group of 200 children and adults with asthma as well as that of 2000 healthy subjects as controls. The most common blood group among the patients and controls was “O” (43.5% and 43.6%, respectively), followed by B, A, and AB. In the distribution of different blood groups, nonsignificant difference between patients and controls was observed (p = 0.931). We conclude that ABO blood group status has a nonsignificant association with asthma among the population of Mysore, Karnataka, South India.
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Acknowledgments
The authors profusely thank the doctors, the patients, and the families of the patients of Cheluvamba Hospital, J.S.S. Hospital, and the director and staff of the Allergy, Asthma and Chest Center, Krishnamurthypuram, and the Blood Bank of K.R. Hospital. Our thanks also go to Dr. D. Venkatesha, Principal of Mysore Medical College and Research Institute; Dr. S. K. Chaya and Mrs. Sumithra of J.S.S. Hospital; Dr. Rajendra Kumar; and Dr. Pradeep Kumar and Mr. Kareem Khan M. of Cheluvamba Hospital for their invaluable guidance in the collection of data and Prof. Suresh Holla. Mr. Mahdi Bijanzadeh is grateful to the Chairman of the Department of Studies in Zoology, University of Mysore, and Ahwaz University of Medical Sciences, Iran, for providing facilities to perform this work.
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Bijanzadeh, M., Ramachandra, N.B., Mahesh, P.A. et al. Lack of Association Between Asthma and ABO Blood Group. Lung 187, 389–392 (2009). https://doi.org/10.1007/s00408-009-9175-1
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DOI: https://doi.org/10.1007/s00408-009-9175-1