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Thoracic outlet syndrome in 3T MR neurography—fibrous bands causing discernible lesions of the lower brachial plexus

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Abstract

Objectives

To investigate whether targeted magnetic resonance neurography (MRN) of the brachial plexus can visualise fibrous bands compressing the brachial plexus and directly detect injury in plexus nerve fascicles.

Methods

High-resolution MRN was employed in 30 patients with clinical suspicion of either true neurogenic thoracic outlet syndrome (TOS) or non-specific TOS. The protocol for the brachial plexus included a SPACE (3D turbo spin echo with variable flip angle) STIR (short tau inversion recovery), a sagittal-oblique T2-weighted (T2W) SPAIR (spectral adiabatic inversion recovery) and a 3D PDW (proton density weighted) SPACE. Images were evaluated for anatomical anomalies compressing the brachial plexus and for abnormal T2W signal within plexus elements. Patients with abnormal MR imaging findings underwent surgical exploration.

Results

Seven out of 30 patients were identified with unambiguous morphological correlates of TOS. These were verified by surgical exploration. Correlates included fibrous bands (n = 5) and pseudarthrosis or synostosis of ribs (n = 2). Increased T2W signal was detected within compressed plexus portion (C8 spinal nerve, inferior trunk, or medial cord) and confirmed the diagnosis.

Conclusions

The clinical suspicion of TOS can be diagnostically confirmed by MRN. Entrapment of plexus structures by subtle anatomical anomalies such as fibrous bands can be visualised and relevant compression can be confirmed by increased T2W signal of compromised plexus elements.

Key Points

• MR neurography (MRN) can aid the diagnosis of thoracic outlet syndrome (TOS).

• Identifiable causes of TOS in MRN include fibrous bands and bony anomalies.

• Increased T2W signal within brachial plexus elements indicate relevant nerve compression.

• High positive predictive value allows confident and targeted indication for surgery.

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Abbreviations

TOS:

Thoracic outlet syndrome

MRN:

Magnetic resonance neurography

ENG:

Electroneurography

EMG:

Electromyography

PDW:

Proton density weighted

SPACE:

3D turbo spin echo with variable flip angle

STIR:

Short tau inversion recovery

SPAIR:

Spectral adiabatic inversion recovery

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Acknowledgments

This study was supported by Postdoctoral Fellowships granted to P.B. and M.P. from the Medical Faculty of the University of Heidelberg, and a grant to M.P. and M.B. from the German Osteoarthritis Foundation (Deutsche-Arthrose-Hilfe e.V., Grant number P215-A482).

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Authors and Affiliations

  1. Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany

    P. Baumer, M. Bendszus & M. Pham

  2. Centre for Neurology and Clinical Neurophysiology, Neuer Wall, Hamburg, Germany

    H. Kele

  3. Department of Neurosurgery, Oldenburg Evangelical Hospital, Oldenburg University, Oldenburg, Germany

    T. Kretschmer

  4. Department of Neurosurgery, Ulm University Hospital/Bezirkskrankenhaus Guenzburg, Günzburg, Germany

    R. Koenig & M. Pedro

Authors
  1. P. Baumer
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  2. H. Kele
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  3. T. Kretschmer
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  4. R. Koenig
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  5. M. Pedro
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  6. M. Bendszus
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  7. M. Pham
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Correspondence to P. Baumer.

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Baumer, P., Kele, H., Kretschmer, T. et al. Thoracic outlet syndrome in 3T MR neurography—fibrous bands causing discernible lesions of the lower brachial plexus. Eur Radiol 24, 756–761 (2014). https://doi.org/10.1007/s00330-013-3060-2

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  • DOI: https://doi.org/10.1007/s00330-013-3060-2

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