Abstract
Peste des petits ruminants virus (PPRV) one of the most important viruses of small ruminants has a restricted host range. We report here the presence of PPRV virus in the nasal swabs of 3 out of 12 dogs in a routine microarray screening. The presence of PPRV sequence was further confirmed by PCR and sequencing. The sequence analysis revealed that the PPRV virus has close similarities with the viruses present in Indian subcontinent but was not identical to the vaccine virus used in India. Results suggest possible crossing of species barrier but requires further serological evidences.
Similar content being viewed by others
References
Abdollahpour G, Raoofi A, Najafi J et al (2006) Clinical and para-clinical findings of a recent outbreaks of peste des petits ruminants in Iran. J Vet Med Ser B 53:14–16. doi:10.1111/j.1439-0450.2006.01013.x
Abraham G, Sintayehu A, Libeau G et al (2005) Antibody seroprevalences against peste des petits ruminants (PPR) virus in camels, cattle, goats and sheep in Ethiopia. Prev Vet Med 70:51–57. doi:10.1016/j.prevetmed.2005.02.011
Appel MJ, Yates RA, Foley GL et al (1994) Canine distemper epizootic in lions, tigers, and leopards in North America. J Vet Diagn Invest 6:277–288
Balamurugan V, Sen A, Venkatesan G et al (2010) Sequence and phylogenetic analyses of the structural genes of virulent isolates and vaccine strains of peste des petits ruminants virus from India. Transbound Emerg Dis 57:352–364. doi:10.1111/j.1865-1682.2010.01156.x
Balamurugan V, Sen A, Venkatesan G et al (2012) Peste des petits ruminants virus detected in tissues from an Asiatic lion (Panthera leo persica) belongs to Asian lineage IV. J Vet Sci 13:203. doi:10.4142/jvs.2012.13.2.203
Bao J, Wang Z, Li L et al (2011) Detection and genetic characterization of peste des petits ruminants virus in free-living bharals (Pseudois nayaur) in Tibet, China. Res Vet Sci 90:238–240. doi:10.1016/j.rvsc.2010.05.031
Barrett T, Visser IK, Mamaev L et al (1993) Dolphin and porpoise morbilliviruses are genetically distinct from phocine distemper virus. Virology 193:1010–1012
Barrett T (1999) Morbillivirus infections, with special emphasis on morbilliviruses of carnivores. Vet Microbiol 69:3–13
Blixenkrone-Möller M, Svansson V, Appel M et al (1992) Antigenic relationships between field isolates of morbilliviruses from different carnivores. Arch Virol 123:279–294
Chen EC, Miller SA, DeRisi JL, Chiu CY (2011) Using a pan-viral microarray assay (Virochip) to screen clinical samples for viral pathogens. J Vis Exp. doi:10.3791/2536
Cosby SL (2012) Morbillivirus cross-species infection: is there a risk for humans? Future Virol 7:1103–1113. doi:10.2217/fvl.12.103
Harder TC, Kenter M, Appel MJ et al (1995) Phylogenetic evidence of canine distemper virus in Serengeti’s lions. Vaccine 13:521–523
Harder TC, Osterhaus AD (1997) Canine distemper virus—a morbillivirus in search of new hosts? Trends Microbiol 5:120–124. doi:10.1016/S0966-842X(97)01010-X
Kato SI, Nagata K, Takeuchi K (2012) Cell tropism and pathogenesis of measles virus in monkeys. Front Microbiol 3:14. doi:10.3389/fmicb.2012.00014
Khalafalla AI, Saeed IK, Ali YH et al (2010) An outbreak of peste des petits ruminants (PPR) in camels in the Sudan. Acta Trop 116:161–165. doi:10.1016/j.actatropica.2010.08.002
Lembo T, Oura C, Parida S et al (2013) Peste des petits ruminants infection among cattle and wildlife in northern Tanzania. Emerg Infect Dis 19:2037–2040. doi:10.3201/eid1912.130973
Ludlow M, Rennick LJ, Nambulli S et al (2014) Using the ferret model to study morbillivirus entry, spread, transmission and cross-species infection. Curr Opin Virol 4:15–23. doi:10.1016/j.coviro.2013.11.001
Mamaev LV, Denikina NN, Belikov SI et al (1995) Characterisation of morbilliviruses isolated from Lake Baikal seals (Phoca sibirica). Vet Microbiol 44:251–259
Mamaev LV, Visser IK, Belikov SI et al (1996) Canine distemper virus in Lake Baikal seals (Phoca sibirica). Vet Rec 138:437–439
Mondal B, Sen A, Chand K et al (2009) Evidence of mixed infection of peste des petits ruminants virus and bluetongue virus in a flock of goats as confirmed by detection of antigen, antibody and nucleic acid of both the viruses. Trop Anim Health Prod 41:1661–1667. doi:10.1007/s11250-009-9362-3
Nielsen O, Stewart RE, Measures L et al (2000) A morbillivirus antibody survey of Atlantic walrus, narwhal and beluga in Canada. J Wildl Dis 36:508–517. doi:10.7589/0090-3558-36.3.508
OIE A (2015) OIE World Animal Health Information System. In: Weekly Animal Disease Service Global Report. http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsummary?fupser=&dothis=&reportid=17998. Accessed 7 Jan 2016
Qiu W, Zheng Y, Zhang S et al (2011) Canine distemper outbreak in rhesus monkeys, China. Emerg Infect Dis 17:1541–1543. doi:10.3201/eid1708.101153
Rima BK, Wishaupt RG, Welsh MJ, Earle JA (1995) The evolution of morbilliviruses: a comparison of nucleocapsid gene sequences including a porpoise morbillivirus. Vet Microbiol 44:127–134
Rizantseva N (1956) Experimental measles in puppies. Zh Mikrobiol Epidemiol Immunobiol 27:22–29
Saito TB, Alfieri AA, Wosiacki SR et al (2006) Detection of canine distemper virus by reverse transcriptase-polymerase chain reaction in the urine of dogs with clinical signs of distemper encephalitis. Res Vet Sci 80:116–119. doi:10.1016/j.rvsc.2005.03.002
Sharma B, Pokhriyal M, Rai GK et al (2012) Isolation of Newcastle disease virus from a non-avian host (sheep) and its implications. Arch Virol 157:1565–1567. doi:10.1007/s00705-012-1317-8
Singh RP, Saravanan P, Sreenivasa BP et al (2004) Prevalence and distribution of peste des petits ruminants virus infection in small ruminants in India. Rev Sci Tech 23:807–819
Yadav BS, Pokhriyal M, Vasishtha DP, Sharma B (2014) Animal viruses probe dataset (AVPDS) for microarray-based diagnosis and identification of viruses. Curr Microbiol 68:301–304. doi:10.1007/s00284-013-0477-4
Acknowledgments
The authors (BR, MP, MS, BS) acknowledge the financial support of Indian Council of Agricultural Research.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
The authors have no conflict of interest.
Human Rights and Animal Rights and Informed Consent
The samples used in this study were taken from animals after obtaining informed consent from the owners in their presence.
Rights and permissions
About this article
Cite this article
Ratta, B., Pokhriyal, M., Singh, S.K. et al. Detection of Peste Des Petits Ruminants Virus (PPRV) Genome from Nasal Swabs of Dogs. Curr Microbiol 73, 99–103 (2016). https://doi.org/10.1007/s00284-016-1030-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00284-016-1030-z