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Stir-bar-sorptive extraction and ultra-high-performance liquid chromatography–tandem mass spectrometry for simultaneous analysis of UV filters and antimicrobial agents in water samples

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Abstract

Stir-bar-sorptive extraction (SBSE) with liquid desorption (LD) and ultra-high-performance liquid chromatography–electrospray ionization triple-quadrupole tandem mass spectrometry (UHPLC–(ESI)MS–MS) were used for analysis of six personal care products in environmental water: four UV filters (2,2-dihydroxy-4-methoxybenzophenone, benzophenone-3, octocrylene, and octyldimethyl-p-aminobenzoic acid) and two antimicrobial agents (triclocarban and triclosan). Experimental conditions that affect SBSE-LD sorption efficiency (extraction time and temperature, sample pH, and ionic strength) and desorption efficiency (solvent, temperature, and time) were optimized. The method proved to be sensitive—a 50-mL sample was used to determine these compounds in environmental waters at trace levels. The detection limits of the analytical method were 2.5 ng L−1 for river water and 5–10 ng L−1 for effluent and influent sewage water. In river waters, benzophenone-3 was found at levels from 6 ng L−1 to 28 ng L−1 and triclosan at levels <LOQ. Benzophenone-3 was found between 75 and 127 ng L−1 in influent sewage, whereas concentrations of benzophenone-3 and triclosan were commonly below 25 ng L−1 in effluent sewage.

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Acknowledgement

This study was funded by the Dirección General de Investigación of the Spanish Ministry of Science and Technology, project CTM2008-06847-C02-01/TECNO.

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Authors and Affiliations

  1. Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Marcel·lí Domingo s/n, Sescelades Campus, 43007, Tarragona, Spain

    Marta Pedrouzo, Francesc Borrull, Rosa Maria Marcé & Eva Pocurull

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  1. Marta Pedrouzo
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  2. Francesc Borrull
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  3. Rosa Maria Marcé
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  4. Eva Pocurull
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Corresponding author

Correspondence to Rosa Maria Marcé.

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Pedrouzo, M., Borrull, F., Marcé, R.M. et al. Stir-bar-sorptive extraction and ultra-high-performance liquid chromatography–tandem mass spectrometry for simultaneous analysis of UV filters and antimicrobial agents in water samples. Anal Bioanal Chem 397, 2833–2839 (2010). https://doi.org/10.1007/s00216-010-3743-3

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  • DOI: https://doi.org/10.1007/s00216-010-3743-3

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