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Saying no until the moment is right: initiating ECMO in the EOLIA era

  • Less is more in Intensive Care
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References

  1. Karagiannidis C, Brodie D, Strassmann S, Stoelben E, Philipp A, Bein T, Muller T, Windisch W (2016) Extracorporeal membrane oxygenation: evolving epidemiology and mortality. Intensive Care Med 42:889–896

    Article  CAS  Google Scholar 

  2. Davies A, Jones D, Bailey M, Australia and New Zealand Extracorporeal Membrane Oxygenation (ANZ ECMO) Influenza Investigators et al (2009) Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome. JAMA 302:1888–1895

    Article  CAS  Google Scholar 

  3. Peek GJ, Mugford M, Tiruvoipati R et al (2009) Efficacy and economic assessment of conventional ventilator support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomized controlled trial. Lancet 374:1351–1363

    Article  Google Scholar 

  4. Combes A, Hajage D, Capellier G et al (2018) Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med 378:1965–1975

    Article  Google Scholar 

  5. Auriemma CL, van den Berghe G, Halpern SD (2019) Less is more in critical care is supported by evidence-based medicine. Intensive Care Med 45:1806–1809

    Article  Google Scholar 

  6. MacLaren G, Combes A, Bartlett RH (2012) Contemporary extracorporeal membrane oxygenation for adult respiratory failure: life support in the new era. Intensive Care Med 38:210–220

    Article  Google Scholar 

  7. Brodie D, Slutsky AS, Combes A (2019) Extracorporeal life support for adults with respiratory failure and related indications: a review. JAMA 322:557–568

    Article  Google Scholar 

  8. MacLaren G, Schlapbach LJ, Aiken AM (2020) Nosocomial infections during extracorporeal membrane oxygenation in neonatal, pediatric, and adult patients: a comprehensive narrative review. Pediatr Crit Care Med 21:283–290

    Article  Google Scholar 

  9. Abrams D, Grasselli G, Schmidt M, Mueller T, Brodie D (2020) ECLS-associated infections in adults: what we know and what we don’t yet know. Intensive Care Med 46:182–191

    Article  Google Scholar 

  10. Guerin C, Reignier J, Richard JC et al (2013) Prone positioning in severe acute respiratory distress syndrome. N Engl J Med 368:2159–2168

    Article  CAS  Google Scholar 

  11. Aoyama H, Uchida K, Aoyama K et al (2019) Assessment of therapeutic interventions and lung protective ventilation in patients with moderate to severe acute respiratory distress syndrome: a systematic review and network meta-analysis. JAMA Netw Open 2:e198116

    Article  Google Scholar 

  12. Bellani G, Laffey JG, Pham T et al (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315:788–800

    Article  CAS  Google Scholar 

  13. The National Heart, Lung, and Blood Institute PETAL Clinical Trials Network (2019) Early neuromuscular blockade in the acute respiratory distress syndrome. N Engl J Med 380:1997–2008

    Article  Google Scholar 

  14. Guervilly C, Prud’homme E, Pauly V, Bourenne J, Hraiech S, Daviet F, Adda M, Coiffard B, Forel JM, Roch A, Persico N, Papazian L (2019) Prone positioning and extracorporeal membrane oxygenation for severe acute respiratory distress syndrome: time for a randomized trial? Intensive Care Med 45:1040–1042

    Article  Google Scholar 

  15. Papazian L, Forel JM, Gacouin A et al (2010) Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 363:1107–1116

    Article  CAS  Google Scholar 

  16. Abrams D, Ferguson ND, Brochard L, Fan E, Mercat A, Combes A, Pellegrino V, Schmidt M, Slutsky AS, Brodie D (2019) ECMO for ARDS: from salvage to standard of care? Lancet Respir Med 7:108–110

    Article  Google Scholar 

  17. Ramanathan KR, Tan CS, Rycus P et al (2020) Extracorporeal membrane oxygenation in pregnancy: an analysis of the Extracorporeal Life Support Organization registry. Crit Care Med 48:696–703

    Article  Google Scholar 

  18. Goligher EC, Tomlinson G, Hajage D et al (2018) Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome and posterior probability of mortality benefit in a Post hoc Bayesian analysis of a randomized clinical trial. JAMA 320:2251–2259

    Article  Google Scholar 

  19. Munshi L, Walkey A, Goligher E et al (2019) Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis. Lancet Respir Med 7:163–172

    Article  Google Scholar 

  20. Writing Group for the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial (ART) Investigators (2017) Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs low PEEP on mortality in patients with acute respiratory distress syndrome: a randomized clinical trial. JAMA 318:1335–1345

    Article  Google Scholar 

  21. Fernando SM, Qureshi D, Tanuseputro P, Fan E, Munshi L, Rochwerg B, Talarico R, Scales DC, Brodie D, Dhanani S, Guerguerian AM, Shemie SD, Thavorn K, Kyeremanteng K (2019) Mortality and costs following extracorporeal membrane oxygenation in critically ill adults: a population-based cohort study. Intensive Care Med 45:1580–1589

    Article  Google Scholar 

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Funding

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Author information

Authors and Affiliations

  1. Cardiothoracic Intensive Care Unit, National University Health System, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore

    Graeme MacLaren

  2. Paediatric Intensive Care Unit, Department of Paediatrics, University of Melbourne, The Royal Children’s Hospital, Flemington Rd, Parkville, VIC, 3052, Australia

    Graeme MacLaren

  3. Sorbonne University, INSERM Unite Mixte de Recherche (UMRS) 1166, Institute of Cardiometabolism and Nutrition, Paris, France

    Alain Combes

  4. Service de Medecine Intensive-Reanimation, Institut de Cardiologie, Assistance Publique-Hopitaux de Paris (APHP) Hopital Pitie-Salpetriere, Paris, France

    Alain Combes

  5. Columbia University College of Physicians and Surgeons/New York-Presbyterian Hospital, New York, USA

    Daniel Brodie

  6. Center for Acute Respiratory Failure, New York-Presbyterian Hospital, New York, USA

    Daniel Brodie

Authors
  1. Graeme MacLaren
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  2. Alain Combes
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  3. Daniel Brodie
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Contributions

GM wrote the initial draft. AC and DB critically revised the manuscript for important intellectual content. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Graeme MacLaren.

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Conflicts of interest

AC and DB were both investigators in the EOLIA study. AC is a section editor of this Journal. DB receives research support from ALung Technologies; he was previously on their advisory board. He has been on the medical advisory boards for Baxter, BREETHE, Xenios, and Hemovent. GM has no conflicts of interest.

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MacLaren, G., Combes, A. & Brodie, D. Saying no until the moment is right: initiating ECMO in the EOLIA era. Intensive Care Med 46, 1894–1896 (2020). https://doi.org/10.1007/s00134-020-06185-1

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  • DOI: https://doi.org/10.1007/s00134-020-06185-1

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