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Cross-reactivity betweenCoxiella burnetii and chlamydiae

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Abstract

A cross-reactivity among some strains ofCoxiella burnetii and chlamydiae with immune rabbit and mouse sera in ELISA and immunoblot analysis was observed. In the latter, the cross-reactivity disappeared after a treatment ofC. burnetii orC. psittaci with proteinase K, which indicates that only proteins were involved. The observed cross-reactivity was not influenced by host chick embryo yolk sac proteins. After adsorption of immune rabbit sera with homologous corpuscular antigens the cross-reactivity disappeared. The possibility of influence of such cross-reactivity on serological diagnosis ofC. burnetii or chlamydiae infections is discussed.

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Abbreviations

Cp 6BC:

C. psittaci strain 6BC

Cp EPO:

C. psittaci strain EPO

Ct Vy:

C. trachomatis isolate Vy

Cb NM I:

C. burnetii strain Nine Mile, phase I

Cb NM II:

C. burnetii strain Nine Mile, phase II

Cb Prisc I:

C. burnetii strain Priscilla, phase I

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Authors and Affiliations

  1. Institute of Virology, Slovak Academy of Sciences, 842 46, Bratislava, Slovakia

    M. Lukáčová & J. Melničáková

  2. Institute of Preventive and Clinical Medicine, 833 01, Bratislava, Slovakia

    J. Kazár

Authors
  1. M. Lukáčová
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  2. J. Melničáková
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  3. J. Kazár
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Correspondence to M. Lukáčová.

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Lukáčová, M., Melničáková, J. & Kazár, J. Cross-reactivity betweenCoxiella burnetii and chlamydiae. Folia Microbiol 44, 579–584 (1999). https://doi.org/10.1007/BF02816263

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