Log in

In vivo andin vitro dermal penetration of lipophilic and hydrophilic pesticides in mice

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (France)

Instant access to the full article PDF.

References

  • Bronaugh RL, Maibach HI (1983)In vitro percutaneous absorption. In: Marzulli FN, Maibach HI (eds) Dermal Toxicology. Hemisphere Publishing Co. pp 117–129

  • Bronaugh RL, Steward RF, Giles AC (1982) Methods forin vitro percutaneous absorption studies. Conparison within vivo results. Toxicol Appl Pharmacol 62:474–480

    Google Scholar 

  • Feldmann JJ, Maibach HI (1970) Absorption of some organic compounds through the skin in man. J Invest Derrnatol 54:399–404

    Google Scholar 

  • Franz TJ (1975) Percutaneous absorption. On the relevance ofin vitro data. J Invest Dermatol 64:190–195

    Google Scholar 

  • Grissom Jr RE, Brownie C, Guthrie FE (1985) Dermal absorption of pesticides in mice. Pestic Biochem Physiol 24:119–123

    Google Scholar 

  • Hawkins GS, Reifenrath WG (1984) Development of anin vitro model for determining the fate of chemicals applied to skin. Fund Appl Toxicol 4:S133-S144

    Google Scholar 

  • Kaminiski NE, Wells DE, Dauterman WC, Roberts JF, Guthrie FE (1986) Uptake of lipoprotein-bound toxicant. A potential route of immunotoxicology. Toxicol Appl Pharmacol 82:474–480

    Google Scholar 

  • Kao J, Patterson FK, Hall J (1985) Skin penetration and metabolism of topically applied chemicals in six mammalian species, including man: An in vitro study with benzo[a]pyrene and testosterone. Toxicol Appl Pharmacol 81:502–516

    Google Scholar 

  • Maliwal BP, Guthrie FE (1982)In vitro uptake and transfer of chlorinated hydrocarbons among human lipoproteins. J Lipid Res 23:474–479

    Google Scholar 

  • Montagna W (1971) Cutaneous comparative biology. Arch Derm 104:577–591

    Google Scholar 

  • Scheuplein RJ, Blank IH (1971) Permeability of the skin. Physiol Rev 51:702–747

    Google Scholar 

  • Snedecor GW, Cochran WG (1980) Statistical Methods. Iowa State University Press, Ames, Iowa

    Google Scholar 

  • Tregear RT (1966) Physical Functions of Skin. Academic Press, New York 12–13

    Google Scholar 

  • Wester RC, Maibach HI (1983) Cutaneous pharmacokinetics: 10 steps to percutaneous absorption. Drug Metab Rev 14:169–205

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grissom, R.E., Brownie, C. & Guthrie, F.E. In vivo andin vitro dermal penetration of lipophilic and hydrophilic pesticides in mice. Bull. Environ. Contam. Toxicol. 38, 917–924 (1987). https://doi.org/10.1007/BF01609073

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01609073

Keywords

Navigation