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High-intensity lesion on T1-weighted MR images in neurofibromatosis type 1: a case of premalignant lesion

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Summary

We report a patient with NF1, who was followed up because of an optic glioma and one enhancing lesion presumed to be a pilocytic astrocytoma. T1- and T2-weighted MR images showed also a hyperintense periventricular lesion with no enhancement and no mass effect, of an unsuspected nature. Three years later a glioblastoma multiforme developed at the site of this preceding lesion.

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Authors and Affiliations

  1. Department of Neuroradiology “Charcot”, Salpêtrière Hospital, Paris

    Y. Miaux, A. Guermazi & J. Chiras

  2. Department of Neurosurgery, Salpêtrière Hospital, Paris

    P. Cornu

  3. Department of Neuropathology, Salpêtrière Hospital, Paris

    K. Mokhtari

  4. Department of Radiology, Saint-Louis Hospital, Paris, France

    A. Guermazi

  5. Department of Dermatology, Saint-Louis Hospital, Paris, France

    B. Singer & C. Blanchet-Bardon

Authors
  1. Y. Miaux
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  2. A. Guermazi
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  3. P. Cornu
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  4. K. Mokhtari
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  5. B. Singer
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  6. J. Chiras
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  7. C. Blanchet-Bardon
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Miaux, Y., Guermazi, A., Cornu, P. et al. High-intensity lesion on T1-weighted MR images in neurofibromatosis type 1: a case of premalignant lesion. Acta neurochir 139, 1085–1087 (1997). https://doi.org/10.1007/BF01411565

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  • DOI: https://doi.org/10.1007/BF01411565

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