Log in

Duodenogastrischer Reflux nach Vagotomie und Pyloroplastik

Duodenogastric reflux after vagotomy and pyloroplasty

  • Published:
Langenbecks Archiv für Chirurgie Aims and scope Submit manuscript

Summary

In 27 patients after selective or truncal vagotomy and pyloroplasty the occurrence of duodenogastric reflux was checked by two methods, by the measurement of Bromsulphalein (BSP)-concentration in the gastric aspirate after BSP was given intravenously and by instillation of a barium meal in the second part of the duodenum followed by upper GI-series. In 20 of 23 patients reflux was recorded radiologically, in 18 of 27 patients reflux was shown by the BSP-Method.

Proven bile reflux was associated with major postoperative discomfort, such as epigastric fullness, nausea and epigastric pain, it was also associated with gastritis as shown by microscopic examination of biopsies taken from the antrum.

It is recommended to consider duodenogastric reflux as a possible reason for patients complaints after vagotomy and pyloroplasty. To avoid those complaints the preference of proximal gastric vagotomy without pyloroplasty is supported, if preoperative gastric emptying is not impaired.

Zusammenfassung

Bei 27 Patienten mit selektiver oder trunkulärer Vagotomie und Pyloroplastik wurde geprüft, ob ein duodenogastrischer Reflux vorliegt. Die Untersuchung erfolgte röntgenologisch durch Instillation von verdünntem Bariumbrei in das Duodenum und durch Nachweis von i.v. appliziertem Bromsulphalein im Magensaft. Es konnte bei 20 von 23 Patienten röntgenologisch und bei 18 von 27 Patienten durch den Bromsulphalein-Nachweis ein duodenogastrischer Reflux festgestellt werden. In Zusammenhang mit Reflux standen postoperative Beschwerden wie Völlegefühl, Brechreiz und Oberbauchschmerzen, sowie der Nachweis morphologischer Veränderungen der Magenschleimhaut im Sinne von Gastritiden verschiedener Stadien.

Es wird empfohlen, bei Beschwerden nach Vagotomie und Pyloroplastik auch an einen duodenogastrischen Reflux als ögliche Ursache zu denken. Zur Vermeidung solcher Beschwerden wird bei präoperativ normaler Magenentleerung die proximal gastrale Vagotomie ohne Pyloroplastik empfohlen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Blum, A. L., Fasel, J.: Die elektive Chirurgie des Ulcus duodeni: ein dreifaches Dilemma. Dtsch. med. Wschr.99, 1033 (1974)

    PubMed  Google Scholar 

  2. Capper, W. M., Airth, G. R., Kilby, J. O.: A test for pyloric regurgitation. Lancet1966 II, 621

    Google Scholar 

  3. Capper, W. M.: Alkaline areas in gastric mucosa after gastric surgery. Gut7, 220 (1966)

    Google Scholar 

  4. Capper, W. M.: Factors in the pathogenesis of gastric ulcer. Ann. roy. Coll. Surg. Engl.40, 21 (1967)

    Google Scholar 

  5. Clarke, R. J., Alexander-Williams, J.: The effect of preserving antral innervation and of a pyloroplasty on gastric emptying after vagotomy in man. Gut14, 300 (1973)

    PubMed  Google Scholar 

  6. Davenport, H. W.: Destruction of the gastric mucosal barrier by detergents and urea. Gastroenterology54, 175 (1968)

    PubMed  Google Scholar 

  7. Drapanas, T., Bethea, M.: Reflux gastritis following gastric surgery. Ann. Surg.179, 618 (1974)

    PubMed  Google Scholar 

  8. Du Plessis, D. J., W'srand, C. M.: Pathogenesis of gastric ulceration. Lancet1965 I, 974

    Google Scholar 

  9. Elster, K.: Pathologisch-anatomisches Bild der Magenkrankheiten. In: L. Demling: Der kranke Magen. München-Berlin-Wien: Urban und Schwarzenberg 1970

    Google Scholar 

  10. Feifel, G., Falkenberg, P., Kemkes, B., Geier, E.: Die Problematik des Insulin-Tests als postoperative Vagotomiekontrolle. Münch. med. Wschr.116, 995 (1974)

    Google Scholar 

  11. Grant, R., Grossmann, M. I., Wang, K. J., Ivy, A. C.: The cytolytic action of some gastrointestinal secretions and enzymes on epithelial cells of the gastric and duodenal mucosa. J. cell. comp. Physiol.37, 137 (1951)

    Google Scholar 

  12. Keighley, M. R. B., Asquith, P., Alexander-Williams, J.: Duodenogastric reflux: A cause of gastric mucosal hyperaemia and symptoms after operations for peptic ulceration. Gut16, 28 (1975)

    PubMed  Google Scholar 

  13. Kilby, J. O.: Duodenogastric reflux and pyloric surgery. Gastroenterology58, 593 (1970)

    PubMed  Google Scholar 

  14. Kimura, K.: Chronological transition of the fundic-pyloric border determined by stepwise biopsy of lesser and greater curvatures of the stomach. Gastroenterology 63, 584 (1972)

    PubMed  Google Scholar 

  15. Lawson, H. H.: Effect of duodenal contents on the gastric mucosa under experimental conditions. Lancet1964 I, 469

    Google Scholar 

  16. Maiwald, L.: Erweiterte Verfahren der Magenfunktionsdiagnostik. In: H. Bartelheimer, H. A. Kühn, V. Becker u. F. Stelzner: Gastroenterologie und Stoffwechsel, Bd. 4. Stuttgart: Thieme 1973

    Google Scholar 

  17. Ottenjann, R.: Neue Aspekte der Pathophysiologie und Therapie der Ulcuskrankheit. Dtsch. med. Wschr.99, 1321 (1974)

    PubMed  Google Scholar 

  18. Ormsbee, H. S., Springfield, A. C., Weddle, C. O., Bass, P.: The effects of liquid test meals and drugs on canine antral-duodenal contractile activity following parietal cell or truncal vagotomy with or without pyloroplasty. Proc. 4th Internat. Symp. Gastroint. Motility, session V, p. 555. Banff 1973

  19. Rhodes, J., Barnardo, D. E., Philipps, S. F., Rovelstad, R. A., Hofman, A. F.: Increased ref lux of bile into the stomach in patients with gastric ulcer. Gastroenterology57, 241 (1969)

    PubMed  Google Scholar 

  20. Smith, G. M.: An experimental study of the relation of bile to ulceration of the mucous membrane on the stomach. J. med. Res.30, 147 (1914)

    Google Scholar 

  21. Van Heerden, J. A., Priestley, J. T., Farrow, G. M., Philipps, S. F.: Postoperative alkaline reflux gastritis. Amer. J. Surg.118, 427 (1969)

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rothmund, M., Deisler, G., Kaufmann, A. et al. Duodenogastrischer Reflux nach Vagotomie und Pyloroplastik. Langenbecks Arch Chiv 340, 167–178 (1976). https://doi.org/10.1007/BF01254854

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01254854

Key words

Navigation