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Are We Giving Unbalanced Amino Acid Solutions?

-From Protein Hydrolysates to Tailored Solutions-

  • Chapter
Metabolic Support of the Critically Ill Patient

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 17))

Abstract

It has been known for more than 50 years that a severe traumatic injury gives rise to striking changes in metabolism. In particular, there is a marked increase in nitrogen (N) excretion indicating net protein catabolism and an enhanced oxygen utilization, demonstrating increased oxidation of energy substrates [1]. Recent developments in nutritional support of such patients have enabled body mass to be preserved while healing occurs [2]. Today consensus has been reached that amino acid nutrition beneficially affects net nitrogen balance during episodes of trauma, injury or infection [3–6]. Negative N-balance after severe trauma or injury can therefore be minimized if large amounts of amino acid N together with energy substrates are provided by the intravenous route [5, 7].

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Authors
  1. P. Fürst
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  2. P. Stehle
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Editors and Affiliations

  1. Laboratory for Surgical Metabolism, Brigham and Women’s Hospital, 75 Francis Street, Boston, Massachussetts, 02115, USA

    Douglas W. Wilmore

  2. L. Deloyers Laboratory for Experimental Surgery, Free University of Brussels, Avenue J. Wybran 40, 1070, Brussels, Belgium

    Yvon A. Carpentier

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© 1993 Springer-Verlag Berlin Heidelberg

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Fürst, P., Stehle, P. (1993). Are We Giving Unbalanced Amino Acid Solutions?. In: Wilmore, D.W., Carpentier, Y.A. (eds) Metabolic Support of the Critically Ill Patient. Update in Intensive Care and Emergency Medicine, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85011-0_7

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  • DOI: https://doi.org/10.1007/978-3-642-85011-0_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85013-4

  • Online ISBN: 978-3-642-85011-0

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