Abstract
From time immemorial, plants have been an inexhaustible source of healing extracts for suffering mankind. Modern drug research has made it possible to isolate and identify the active principles of these extracts and to specify their dose-response relationships. In this way it has become possible to verify the phytotherapeutic action of ancient drugs. Nowadays large screening programs are running in many pharmaceutical companies in order to select new active principles from thousands of plant species. But only few companies have realized that plant cell culture is also a rich source of new active substances [1] and a potent technique to produce natural compounds like shi-konin and rosmarinic acid. Its chemical structure was determined in 1958 [2] and its isolation from plant cell lines of Coleus blumei Benth. was reported in 1977 [3,4]. Today we are able to present a procedure of unparalleled high production of rosmarinic acid with our cell line CBL 2B of Coleus blumei Benth.
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© 1985 Springer-Verlag Berlin Heidelberg
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Ulbrich, B., Wiesner, W., Arens, H. (1985). Large-Scale Production of Rosmarinic Acid from Plant Cell Cultures of Coleus blumei Benth.. In: Neumann, KH., Barz, W., Reinhard, E. (eds) Primary and Secondary Metabolism of Plant Cell Cultures. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70717-9_28
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DOI: https://doi.org/10.1007/978-3-642-70717-9_28
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