3D FractalNet: Dense Volumetric Segmentation for Cardiovascular MRI Volumes

  • Conference paper
  • First Online:
Reconstruction, Segmentation, and Analysis of Medical Images (RAMBO 2016, HVSMR 2016)

Abstract

Cardiac image segmentation plays a crucial role in various medical applications. However, differentiating branchy structures and slicing fuzzy boundaries from cardiovascular MRI volumes remain very challenging tasks. In this paper, we propose a novel deeply-supervised 3D fractal network for efficient automated whole heart and great vessel segmentation in MRI volumes. The proposed 3D fractal network takes advantage of fully convolutional architecture to perform efficient, precise and volume-to-volume prediction. Notably, by recursively applying a single expansion rule, we construct our network in a novel self-similar fractal scheme and thus promote it in combining hierarchical clues for accurate segmentation. More importantly, we employ deep supervision mechanism to alleviate the vanishing gradients problem and improve the training efficiency of our network on small medical image dataset. We evaluated our method on the HVSMR 2016 Challenge dataset. Extensive experimental results demonstrated the superior performance of our method, ranking top in both two phases.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
EUR 29.95
Price includes VAT (Germany)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
EUR 42.79
Price includes VAT (Germany)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
EUR 53.49
Price includes VAT (Germany)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Notes

  1. 1.

    See: https://challenge.kitware.com/#challenge/56f421d6cad3a53ead8b1b7e.

References

  1. Chen, H., Dou, Q., Yu, L., Heng, P.A.: Voxresnet: deep voxelwise residual networks for volumetric brain segmentation. ar**v preprint ar**v:1608.05895 (2016)

  2. Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3d u-net: learning dense volumetric segmentation from sparse annotation. ar**v preprint ar**v:1606.06650 (2016)

  3. Dou, Q., Chen, H., **, Y., Yu, L., Qin, J., Heng, P.A.: 3d deeply supervised network for automatic liver segmentation from CT volumes. ar**v preprint ar**v:1607.00582 (2016)

  4. Glorot, X., Bengio, Y.: Understanding the difficulty of training deep feedforward neural networks. Aistats 9, 249–256 (2010)

    Google Scholar 

  5. Jia, Y., Shelhamer, E., Donahue, J., Karayev, S., Long, J., Girshick, R., Guadarrama, S., Darrell, T.: Caffe: convolutional architecture for fast feature embedding. ar**v preprint ar**v:1408.5093 (2014)

  6. Larsson, G., Maire, M., Shakhnarovich, G.: Fractalnet: ultra-deep neural networks without residuals. ar**v preprint ar**v:1605.07648 (2016)

  7. Lee, C.Y., **e, S., Gallagher, P., Zhang, Z., Tu, Z.: Deeply-supervised nets (2015)

    Google Scholar 

  8. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)

    Google Scholar 

  9. Merkow, J., Kriegman, D., Marsden, A., Tu, Z.: Dense volume-to-volume vascular boundary detection. ar**v preprint ar**v:1605.08401 (2016)

  10. Pace, D.F., Dalca, A.V., Geva, T., Powell, A.J., Moghari, M.H., Golland, P.: Interactive whole-heart segmentation in congenital heart disease. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 80–88. Springer, Heidelberg (2015). doi:10.1007/978-3-319-24574-4_10

    Chapter  Google Scholar 

  11. Peters, J., Ecabert, O., Meyer, C., Schramm, H., Kneser, R., Groth, A., Weese, J.: Automatic whole heart segmentation in static magnetic resonance image volumes. In: Ayache, N., Ourselin, S., Maeder, A. (eds.) MICCAI 2007. LNCS, vol. 4792, pp. 402–410. Springer, Heidelberg (2007). doi:10.1007/978-3-540-75759-7_49

    Chapter  Google Scholar 

  12. Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Heidelberg (2015). doi:10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  13. Simonyan, K., Zisserman, A.: Very deep convolutional networks for large-scale image recognition. ar**v preprint ar**v:1409.1556 (2014)

  14. Tran, P.V.: A fully convolutional neural network for cardiac segmentation in short-axis MRI. ar**v preprint ar**v:1604.00494 (2016)

  15. **e, S., Tu, Z.: Holistically-nested edge detection. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 1395–1403 (2015)

    Google Scholar 

  16. Zhuang, X., Rhode, K.S., Razavi, R.S., Hawkes, D.J., Ourselin, S.: A registration-based propagation framework for automatic whole heart segmentation of cardiac MRI. IEEE Trans. Med. Imag. 29(9), 1612–1625 (2010)

    Article  Google Scholar 

Download references

Acknowledgments

The work described in this paper was supported by a grant from the Research Grants Council of the Hong Kong Special Administrative Region (Project no. CUHK 412513).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lequan Yu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Yu, L., Yang, X., Qin, J., Heng, PA. (2017). 3D FractalNet: Dense Volumetric Segmentation for Cardiovascular MRI Volumes. In: Zuluaga, M., Bhatia, K., Kainz, B., Moghari, M., Pace, D. (eds) Reconstruction, Segmentation, and Analysis of Medical Images. RAMBO HVSMR 2016 2016. Lecture Notes in Computer Science(), vol 10129. Springer, Cham. https://doi.org/10.1007/978-3-319-52280-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-52280-7_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-52279-1

  • Online ISBN: 978-3-319-52280-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics

Navigation