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Artificial Membrane Models for the Study of Macromolecular Delivery

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Macromolecular Drug Delivery

Part of the book series: Methods in Molecular Biology ((MIMB,volume 480))

Summary

Artificial biomembrane mimetic model systems are used to characterize peptide–membrane interactions using a wide range of methods. Herein, we present the use of selected membrane model systems to investigate peptide–membrane interactions. We describe methods for the preparation of various membrane mimetic media. Our applications will focus on small unilamellar vesicles (SUVs) and large unilamellar vesicles (LUVs) as well as on media more suited for nuclear magnetic resonance (NMR) techniques, micelles, and fast-tumbling two-component bilayered micelles (bicelles).

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Authors and Affiliations

  1. Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden

    Lena Mäler & Astrid Gräslund

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  1. Lena Mäler
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  2. Astrid Gräslund
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    © 2009 Humana Press, a part of Springer Science+Business Media, LLC

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    Mäler, L., Gräslund, A. (2009). Artificial Membrane Models for the Study of Macromolecular Delivery. In: Belting, M. (eds) Macromolecular Drug Delivery. Methods in Molecular Biology, vol 480. Humana Press. https://doi.org/10.1007/978-1-59745-429-2_9

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    • DOI: https://doi.org/10.1007/978-1-59745-429-2_9

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    • Publisher Name: Humana Press

    • Print ISBN: 978-1-58829-999-4

    • Online ISBN: 978-1-59745-429-2

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