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The Concept of Direct and Indirect Neurotoxicity and the Concept of Toxic Metal/Essential Element Interactions as a Common Biomechanism Underlying Metal Toxicity

  • Chapter
The Vulnerable Brain and Environmental Risks

Abstract

The toxicities of many metals have been well defined. Many of these metals, such as mercury, lead, cadmium, manganese, aluminum, and alkyltin, have demonstrated a special target affinity towards the nervous system.

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  1. Departments of Pathology, Pharmacology, and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 72205, USA

    Louis W. Chang

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  1. Binghamton University, Binghamton, New York, USA

    Robert L. Isaacson

  2. U. S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA

    Karl F. Jensen

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Chang, L.W. (1992). The Concept of Direct and Indirect Neurotoxicity and the Concept of Toxic Metal/Essential Element Interactions as a Common Biomechanism Underlying Metal Toxicity. In: Isaacson, R.L., Jensen, K.F. (eds) The Vulnerable Brain and Environmental Risks. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3330-6_5

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