Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions
Authors (first, second and last of 5)
Collection
Model-Guided Development of Robust, Optimized, and Intensified Pharmaceutical Processes for Drug Products
The papers contained in this special issue aim to enhance process understanding, yield novel and interesting processing insights, and/or enable development of robust, optimal, or intensified pharmaceutical processes. Mechanistic, first principle-based models and their combination with phenomenological process models or machine learning/AI approaches are covered. Please see below for highlighted articles!
Editors
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Ecevit Bilgili
Dr. Ecevit Bilgili is a professor of Chemical Engineering at NJIT. His Particle Engineering and Pharmaceutical Nanotechnology Lab has been conducting research in designing particulate formulations and processes for high-value-added products like pharmaceuticals with enhanced functionalities such as enhanced bioavailability of poorly water-soluble drugs. His research interests center on the development of a fundamental understanding of the mechanisms–transformations involved during the formation of drug nanoparticles via top-down and bottom-up approaches, nanocomposite microparticles, and amorphous solid dispersions.
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Bodhisattwa Chaudhuri
Dr. Chaudhuri holds Professor positions in the Departments of Pharmaceutical Sciences, Chemical and Biomolecular Engineering, and Institute of Material Sciences (IMS) at the University of Connecticut. He is formally trained in Chemical and Mechanical Engineering disciplines and focuses on solving problems of pharmaceutical significance with a rigor of engineering approaches.
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Rohit Ramachandran
Dr. Rohit Ramachandran is presently Associate Professor and Chancellor’s Scholar at the Department of Chemical & Biochemical Engineering at Rutgers University. His research interests are at the interface of process systems engineering and particulate technology. In his academic career, he has published 115 journal papers, 7 book chapters and 7 invited short papers. He has received the 2015 Chemical Engineering Outstanding Faculty Award, the 2017 Rutgers New Brunswick Chancellor-Scholar Award, the 2018 Rutgers Board of Trustees award and the 2019 American Institute of Chemical Engineers (AIChE) Process Development to Manufacturing award.
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Sadegh Poozesh
Dr. Sadegh Poozesh is a Senior Scientist at AstraZeneca.
Articles (10 in this collection)
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On the Applicability of the Coarse Grained Coupled CFD-DEM Model to Predict the Heat Transfer During the Fluidized Bed Drying of Pharmaceutical Granules
Authors (first, second and last of 5)
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New Discrete Formulation for Reduced Population Balance Equation: An Illustration to Crystallization
Authors
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Model-Based Evaluation of Drying Kinetics and Solvent Diffusion in Pharmaceutical Thin Film Coatings
Authors (first, second and last of 4)
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An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions
Authors (first, second and last of 7)
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Multicomponent Droplet Drying Modeling Based on Conservation and Population Balance Equations
Authors (first, second and last of 4)
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Using a Model-based Material Sparing Approach for Formulation and Process Development of a Roller Compacted Drug Product
Authors (first, second and last of 6)
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Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant
Authors (first, second and last of 11)
