Collection

Signaling Cascades and Cell Death Mechanisms in the Central Nervous System

Submission status
Closed

A pathological hallmark of neuropsychiatric disorders is the cell death within the CNS. Particularly, neuronal cell death can cause CNS dysfunction, nerve injury, and degeneration. In addition, neuroinflammation and secondary neurodegeneration usually result from cell death in microglia and astrocytes. Understanding of the signaling pathways and mechanisms underlying CNS cell death may lead to valuable drug targets and therapeutics for prevention and treatment easier to develop. Over the years, various neuronal and vascular protection strategies have been investigated. Disease-modifying drugs that target CNS cell death have yet to be developed. To develop novel effective strategies against CNS cell death and related disorders, more research is needed. The goal of this Topical Collection is to promote research into the pathological roles and molecular mechanisms underlying CNS cell death and related neuropsychiatric disorders, as well as research into novel biomarkers, drug targets, and neuroprotective strategies. We encourage all researchers working in this dynamic field to submit articles and contribute to the success of this collection. Potential topics include but are not limited to the following:

âš« Pathway Analysis within Neuroinflammation

âš« Emerging Approaches to Neuroprotection

âš« Novel Biomarkers of the Neuroinflammation

âš« Repurposing Drugs against Neuroinflammation

âš« Molecular Mechanism of Bioactive Compounds in Neuroprotection

âš« Nano-biotechnology for CNS Diseases

âš« Research and Development with Fast Charging Technology

Editors

  • Dr. Zheng Zachory Wei Dr. Zheng Zachory Wei , 

    Dr. Zheng Zachory Wei

    Dr. Zheng Zachory Wei’s work is focused on stem cell differentiation for tissue biotherapeutics and cell transplantation medicine. For his early career development stage and faculty position in cellular therapeutic medical technology (CTMT) at Emory, he has performed translational research in cognitive disorders and psychiatry following brain injuries. He has knowledge in biomedical manufacturing, critical care medicine, health communication, neurological disease prevention and brain health. Contact: zachorywei@emory.edu; weizz@ctrlyin.org

  • Dr. Tahmineh Mokhtari Dr. Tahmineh Mokhtari  &

    Dr. Tahmineh Mokhtari

    Dr. Tahmineh Mokhtari received her Ph.D. degree in Anatomical Sciences from School of Medicine, Tehran University of Sciences, Tehran, Iran (2017). Now she is working as Research Fellowship at Institute of Psychology, Chinese Academy of Sciences, Bei**g, China. Her work focuses mainly on the study of the neurobiology of pain, in particular its relationship with depression, and the role of neuroinflammatory pathways in the pathogenesis of neuropsychological disorders to investigate new therapeutic approaches. Contact: mokhtari.tmn@mails.ucas.ac.cn

  • Dr. Kailiang Zhou Dr. Kailiang Zhou

    Dr. Kailiang Zhou

    Dr. Kailiang Zhou is an attending physician of spine surgery, associate researcher, lecturer, master supervisor, visiting follower of University of Maryland, the member of Young Orthopaedic Doctors Union of Wu Jie** medical foundation, the first-instance expert of National Natural Science Foundation. He is mainly engaged in basic research in traumatic spinal cord injury, including the microenvironment and programmed cell death in spinal cord injury. Main research: autophagy and spinal cord injury, pyroptosis and spinal cord injury; apoptotic bodies and spinal cord injury. Contact: zhoukailiang@wmu.edu.cn

Articles (5 in this collection)