Abstract
Knowledge graphs play a crucial role in the medical field. Most existing knowledge graphs are manually created by experts or extracted from medical encyclopedias, resulting in the omission of valuable knowledge from medical clinical practice. Entities like diseases and symptoms in medicine exist at different levels, but current knowledge graphs fail to handle the induction and integration of this multi-scale information effectively. In our study, we constructed a knowledge graph that better aligns with real clinical data and effectively integrates multi-scale medical information by performing data preparation, medical entity extraction, negation handling, relation extraction, and graph cleaning. The reliability and rationality of the knowledge graph have been verified through subjective and objective assessments.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Bodenreider, O.: The unified medical language system (UMLs): integrating biomedical terminology. Nucleic Acids Res. 32(suppl_1), D267–D270 (2004)
Cheng, D., Yang, F., Wang, X., Zhang, Y., Zhang, L.: Knowledge graph-based event embedding framework for financial quantitative investments. In: Proceedings of the 43rd International ACM SIGIR Conference on Research and Development in Information Retrieval, pp. 2221–2230 (2020)
Donnelly, K., et al.: SNOMED-CT: the advanced terminology and coding system for ehealth. Stud. Health Technol. Inform. 121, 279 (2006)
Finlayson, S.G., LePendu, P., Shah, N.H.: Building the graph of medicine from millions of clinical narratives. Sci. Data 1(1), 1–9 (2014)
Li, L., et al.: A method to learn embedding of a probabilistic medical knowledge graph: algorithm development. JMIR Med. Inform. 8(5), e17645 (2020)
Li, L., et al.: Real-world data medical knowledge graph: construction and applications. Artif. Intell. Med. 103, 101817 (2020)
Lin, K., Wu, M., Wang, X., Pan, Y.: MEDLedge: a Q &A based system for constructing medical knowledge base. In: 2016 11th International Conference on Computer Science & Education (ICCSE), pp. 485–489. IEEE (2016)
Liu, C., Yu, Y., Li, X., Wang, P.: Application of entity relation extraction method under CRF and syntax analysis tree in the construction of military equipment knowledge graph. IEEE Access 8, 200581–200588 (2020)
Liu, W., Yin, L., Wang, C., Liu, F., Ni, Z., et al.: Multitask healthcare management recommendation system leveraging knowledge graph. J. Healthcare Eng. 2021 (2021)
Rotmensch, M., Halpern, Y., Tlimat, A., Horng, S., Sontag, D.: Learning a health knowledge graph from electronic medical records. Sci. Rep. 7(1), 5994 (2017)
Sang, L., Xu, M., Qian, S., Wu, X.: Knowledge graph enhanced neural collaborative recommendation. Expert Syst. Appl. 164, 113992 (2021)
Shen, Y., et al.: CBN: constructing a clinical Bayesian network based on data from the electronic medical record. J. Biomed. Inform. 88, 1–10 (2018)
Shi, L., et al.: Semantic health knowledge graph: semantic integration of heterogeneous medical knowledge and services. BioMed Res. Int. 2017 (2017)
Yao, L., Mao, C., Luo, Y.: Graph convolutional networks for text classification. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 33, pp. 7370–7377 (2019)
Yu, S., et al.: Bios: an algorithmically generated biomedical knowledge graph. ar**v preprint ar**v:2203.09975 (2022)
Zhang, Z., Zhuang, F., Zhu, H., Shi, Z., **ong, H., He, Q.: Relational graph neural network with hierarchical attention for knowledge graph completion. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 34, pp. 9612–9619 (2020)
Zhao, C., Jiang, J., Guan, Y., Guo, X., He, B.: EMR-based medical knowledge representation and inference via Markov random fields and distributed representation learning. Artif. Intell. Med. 87, 49–59 (2018)
Zhao, C., Jiang, J., Xu, Z., Guan, Y.: A study of EMR-based medical knowledge network and its applications. Comput. Methods Programs Biomed. 143, 13–23 (2017)
Acknowledgments
The work is supported by National Key R &D Program of China (2021ZD0113404).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Zhou, Y., Wang, Z., Li, M., Wu, J. (2024). Constructing a Multi-scale Medical Knowledge Graph from Electronic Medical Records. In: Xu, H., et al. Health Information Processing. CHIP 2023. Communications in Computer and Information Science, vol 1993. Springer, Singapore. https://doi.org/10.1007/978-981-99-9864-7_25
Download citation
DOI: https://doi.org/10.1007/978-981-99-9864-7_25
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-99-9863-0
Online ISBN: 978-981-99-9864-7
eBook Packages: Computer ScienceComputer Science (R0)