Chromophobes

The anterior and intermediate lobes of the pituitary gland include three distinct cell stain types: basophils, acidophils, and chromophobes. Amphophils are a particular kind of chromophobe cell. Epithelial cells, known as amphophils, are located in the anterior and intermediate lobes of the pituitary. These epithelial cells synthesize and release the anterior pituitary’s hormones into the bloodstream. Another form of chromophobe called a melanotroph secretes melanocyte-stimulating hormone (MSH). The parenchyma’s folliculo-stellate cells, which are situated in between the acini, are chromophobe cells as well. They play a significant role in the local homeostatic regulation of pituitary hormone release and possess phagocytic and paracrine capabilities. Nonsecretory chromophobe cell tumors cause hypopituitarism by local compression. Adenomas of somatotroph cells secrete too much growth hormone, which causes acromegaly (enlarged hands, feet, and head) in adults and gigantism in children....