Hypomethylated Genes

Hypomethylation refers to a decrease in the methylation level, a process in which methyl groups (CH₃) are added with the DNA molecule. This can affect the function of genes, and in toxicology, hypomethylation has been associated with the development of certain types of cancer and other health effects. Studies have shown that exposure to certain toxins, such as heavy metals and pollutants, can lead to hypomethylation in specific genes, which may affect the toxic effects observed. To completely comprehend the processes by which hypomethylation contributes to toxicity, however, and to pinpoint particular genes that might be implicated, additional research is required.