Abstract
Drug-induced lung disease, also known as drug-induced lung damage, is the lung damage caused by drugs and their metabolites through direct cytotoxicity or allergic immune reactions, as a part of systemic adverse reactions caused by drugs. Previous studies have reported that lung damage accounts for 6–7% of adverse drug reactions [1]. More than 350 kinds of drugs can cause lung damage. Drugs with lung toxicity include chemotherapy drugs, antibiotics, cardiovascular drugs, nonsteroidal anti-inflammatory drugs, etc. Drug-induced lung damage caused by cytotoxic chemotherapy drugs is the most common. In recent years, drug-induced lung damage has been increasing year by year with the emergence of biological agents, new anti-tumor targeted drugs, and programmed death protein 1 (PD-1) immunotherapy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Kubo K, Wan X. On drug-induced lung damage. Prog Jap Med. 2007;28(3):98–9.
Sun X, Zhu Y, Feng Y, et al. Analysis of anti-tumor targeted drugs induced lung disease. Chin Pharm J. 2018;53(16):1425–30.
Wang Q, Wu X. Clinical manifestations and treatment of immune-related adverse reactions in the therapy by immune checkpoint inhibitors. Chin J Immunol. 2017;33(4):615–20.
Tirumani SH, Ramaiya NH, Keraliya A, et al. Radiographic profiling of immune-related adverse events in advanced melanoma patients treated with ipilimumab. Cancer Immunol Res. 2015;3(10):1185–92.
Ramos-Casals M, Perez-Alvarez R, Perez-de-Lis M, et al. Pulmonary disorders induced by monoclonal antibodies in patients with rheumatologic autoimmune diseases. Am J Med. 2011;124(5):386–94.
Xu Z. Attention to and understanding of drug-induced lung injury should be strengthened. Chin J Tubercul Resp Dis. 2017;40(10):721–3.
Zhao MX, Zhang WF. Early detection value of 18F-FDG-PET/CT for drug-induced lung injury in lymphoma. Ann Hematol. 2019;98(4):909–14.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 Science Press
About this chapter
Cite this chapter
Xu, Y. (2023). Drug-Induced Lung Disease. In: Li, H., Liu, J., Li, L. (eds) Radiology of Infectious and Inflammatory Diseases - Volume 3. Springer, Singapore. https://doi.org/10.1007/978-981-99-4614-3_24
Download citation
DOI: https://doi.org/10.1007/978-981-99-4614-3_24
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-99-4613-6
Online ISBN: 978-981-99-4614-3
eBook Packages: MedicineMedicine (R0)